Francesco Panza,Alessia D&#x;Introno,Anna Maria Colacicco et al.
Francesco Panza et al.
This review will focus on the current knowledge on circulating serum and plasma risk factors of cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin (vascular dementia, VaD) linked to cholesterol homeostasis and li...
Gila Moalem,David J Tracey
Gila Moalem
Tissue damage, inflammation or injury of the nervous system may result in chronic neuropathic pain characterised by increased sensitivity to painful stimuli (hyperalgesia), the perception of innocuous stimuli as painful (allodynia) and spon...
Monica Levy Andersen,Sergio Tufik
Monica Levy Andersen
In this article, we provide a concise review of the past and current literature on the neglected influence of progesterone on male sexual behavior. Although there has been increased interest in all aspects of male sexual function, and the i...
Apolipoprotein E variants and cognition in healthy individuals: a critical opinion [0.03%]
载脂蛋白E变异与健康人的认知：一种批判性观点
Jonathan Savitz,Mark Solms,Rajkumar Ramesar
Jonathan Savitz
The epsilon4 allele of apolipoprotein E (ApoE) is a well-established risk factor for late onset Alzheimer's disease (AD). This knowledge has generated interest in the role of ApoE variants in normal cognition. Varying degrees of cognitive d...
Neuroactive steroid effects on cognitive functions with a focus on the serotonin and GABA systems [0.03%]
神经活性类固醇对认知功能的影响及其对五羟色胺和γ-氨基丁酸系统的作用
Vita Birzniece,Torbjörn Bäckström,Inga-Maj Johansson et al.
Vita Birzniece et al.
This article will review neuroactive steroid effects on serotonin and GABA systems, along with the subsequent effects on cognitive functions. Neurosteroids (such as estrogen, progesterone, and allopregnanolone) are synthesized in the centra...
Cannabinoids, opioids and eating behavior: the molecular face of hedonism? [0.03%]
大麻素、阿片类药物和摄食行为：享乐主义的分子特征？
Daniela Cota,Matthias H Tschöp,Tamas L Horvath et al.
Daniela Cota et al.
Obesity represents nowadays one of the most devastating health threats. Published reports even project a decline in life expectancy of US citizens due to the rapidly increasing prevalence of obesity. This alarming increase is intimately lin...
Manuel F Casanova,Juan Trippe nd
Manuel F Casanova
The developing forebrain exhibits a high degree of spatiotemporal regulation of proliferation and cell cycle exit in progenitor cells of its proliferative zones. This results in the balanced deployment of progenitors between asymmetric divi...
Objective evaluation of manual performance deficits in neurological movement disorders [0.03%]
神经运动障碍的手动性能缺陷的客观评估
Dennis A Nowak,Joachim Hermsdörfer
Dennis A Nowak
Impaired hand function is a frequent finding in movement disorders. The skilled control of prehensile finger forces is an essential feature of tool use in daily life. In healthy subjects, grip force is precisely adjusted to the mechanical o...
L P Morin,C N Allen
L P Morin
The primary mammalian circadian clock resides in the suprachiasmatic nucleus (SCN), a recipient of dense retinohypothalamic innervation. In its most basic form, the circadian rhythm system is part of the greater visual system. A secondary c...
Thyroid hormones and retinoids: a possible link between genes and environment in schizophrenia [0.03%]
甲状腺激素和维甲酸：精神分裂症发病中基因与环境之间可能的联系
Joana Almeida Palha,Ann B Goodman
Joana Almeida Palha
Phenotypic discordance for schizophrenia in monozygotic twins clearly indicates involvement of environmental factors as key determinants in disease development. Positive findings from genome scans, linkage and association studies apply in o...