Inductively Coupled Plasma Mass Spectrometry: Introduction to Analytical Aspects [0.03%]
电感耦合等离子体质谱：分析方面的介绍
Scott C Wilschefski,Matthew R Baxter
Scott C Wilschefski
Inductively coupled plasma mass spectrometry (ICP-MS) is an analytical technique that can be used to measure elements at trace levels in biological fluids. Although older techniques such as atomic absorption and atomic emission are still in...
Indirect Reference Intervals: Harnessing the Power of Stored Laboratory Data [0.03%]
间接参考区间：利用储存的实验室数据的力量
Christopher-John L Farrell,Lan Nguyen
Christopher-John L Farrell
Reference intervals are relied upon by clinicians when interpreting their patients' test results. Therefore, laboratorians directly contribute to patient care when they report accurate reference intervals. The traditional approach to establ...
Kidney Injury Biomarkers in an Academic Hospital Setting: Where Are We Now? [0.03%]
学术医学中心的肾脏损伤生物标志物研究进展如何？
Tirsa T van Duijl,L Renee Ruhaak,Johan W de Fijter et al.
Tirsa T van Duijl et al.
Acute kidney injury (AKI) is a frequent complication in hospitalised patients and is diagnosed by urinary output and serum creatinine. Serum creatinine is an indirect marker for renal glomerular filtration, but lacks specificity for damage ...
Isabelle Mohr,Karl Heinz Weiss
Isabelle Mohr
Wilson disease (WD) is an autosomal recessively-inherited disorder of copper metabolism and characterised by a pathological accumulation of copper. The ATP7B gene encodes for a transmembrane copper transporter essential for biliary copper e...
Nilika Wijeratne,Jillian R Tate,Stephen Du Toit et al.
Nilika Wijeratne et al.
Quantification of co-migrating paraproteins in the beta-region presents an ongoing challenge for laboratories performing serum protein electrophoresis. The between-laboratory variation may impact patient care if the patient uses different p...
Report of the Survey Conducted by RCPAQAP on Current Practice for Paraprotein and Serum Free Light Chain Measurement and Reporting: a Need for Harmonisation [0.03%]
英国皇家病理学家协会蛋白质电泳能力保障计划部门关于本周蛋白和血清游离轻链检测与报告现状的调查报告：建立统一标准的需求
Nilika Wijeratne,Jillian R Tate,Louise Wienholt et al.
Nilika Wijeratne et al.
Clinical laboratory testing is vital in the diagnosis, monitoring and prognostication of monoclonal gammopathies. Although the 2012 recommendations for standardised reporting of protein electrophoresis in Australia and New Zealand aimed to ...
Proposed Addendum to 2012 Recommendations for Standardised Reporting of Protein Electrophoresis in Australia and New Zealand [0.03%]
澳大利亚和新西兰2012年蛋白质电泳标准化报告建议的补充草案
Jillian R Tate,Joel D Smith,Nilika Wijeratne et al.
Jillian R Tate et al.
It is apparent that there is a need for greater harmonisation of the reporting and quantification of paraproteins on protein electrophoresis with the introduction of the electronic health record and recent survey findings indicating ongoing...
Jillian R Tate
Jillian R Tate
The 'paraprotein', also known as M-protein, monoclonal protein and monoclonal component, has stood the test of time as the key biomarker in monoclonal gammopathies. It continues to reinvent itself as new electrophoretic and immunoassay meth...
Gemma M Daley,Carel J Pretorius,Jacobus Pj Ungerer
Gemma M Daley
Plumbism refers to the clinical features of lead toxicity, a condition which has been identified and then forgotten in a depressingly cyclical fashion since ancient times. For the past 6000 years antiquarians have described the human use of...
Faecal Calprotectin [0.03%]
粪钙卫蛋白
Wpn Ganga W Pathirana,Sa Paul Chubb,Melissa J Gillett et al.
Wpn Ganga W Pathirana et al.
Calprotectin is a calcium- and zinc-binding protein of the S-100 protein family which is mainly found within neutrophils and throughout the human body. The presence of calprotectin in faeces is a consequence of neutrophil migration into the...