Mona Botros,Kenneth A Sikaris
Mona Botros
De Ritis described the ratio between the serum levels of aspartate transaminase (AST) and alanine transaminase (ALT) almost 50 years ago. While initially described as a characteristic of acute viral hepatitis where ALT was usually higher th...
Adrenal Diagnostics: An Endocrinologist's Perspective focused on Hyperaldosteronism [0.03%]
从内分泌学视角看肾上腺诊断：以原发性醛固酮增多症为例
Peter J Fuller
Peter J Fuller
The era of sophisticated high resolution imaging with the consequent identification of previously unrecognised adrenal masses (adrenal incidentalomas), has emphasised the need for an appropriate biochemical approach to define adrenal functi...
On-the-Job Evidence-Based Medicine Training for Clinician-Scientists of the Next Generation [0.03%]
针对下一代临床科学家开展基于岗位的循证医学培训
Elaine Yl Leung,Sadia M Malick,Khalid S Khan;EBM-CONNECT Collaboration
Elaine Yl Leung
Clinical scientists are at the unique interface between laboratory science and frontline clinical practice for supporting clinical partnerships for evidence-based practice. In an era of molecular diagnostics and personalised medicine, evide...
Jenny Doust,Paul Glasziou
Jenny Doust
Monitoring tests form an increasing proportion of the workload in clinical biochemistry and biochemists can help by providing clinicians with information about the variability and precision of tests, the time frame for pharmacodynamic stabi...
HbA1c as a Diagnostic Test for Diabetes Mellitus - Reviewing the Evidence [0.03%]
糖化血红蛋白作为诊断糖尿病的检查手段-重审证据
Chris Florkowski
Chris Florkowski
The evidence base in support of HbA1c as a diagnostic test for diabetes mellitus is focused on predicting a clinical outcome, considered to be the pinnacle of the Stockholm Hierarchy applied to reference intervals and clinical decision limi...
Andrew St John,Christopher P Price
Andrew St John
Health economics has been an established feature of the research, policymaking, practice and management in the delivery of healthcare. However its role is increasing as the cost of healthcare begins to drive changes in most healthcare syste...
A Rita Horvath
A Rita Horvath
Laboratory tests offer value if they provide benefit to patients at acceptable costs. Laboratory testing is one of the most widely used diagnostic interventions supporting medical decisions, yet evidence demonstrating its value and impact o...
Tony Badrick
Tony Badrick
Andrew St John
Andrew St John
Point-of-care testing (PoCT) is now possible in many areas of clinical medicine. This review examines the evidence for its application in four areas: self-monitoring; community testing primarily in the pharmacy; general practice; and the em...
The National QAAMS Program - A Practical Example of PoCT Working in the Community [0.03%]
国家QAAMS计划——社区中POCT实用应用的实例分析
Mark Ds Shephard,Janice P Gill
Mark Ds Shephard
The Quality Assurance for Aboriginal and Torres Strait Islander Medical Services (QAAMS) Program is the largest and longest-standing national point-of-care testing (PoCT) program in Australia. With a focus on PoCT for diabetes management, i...