Structure, evolutionary conservation, and functions of angiotensin- and endothelin-converting enzymes [0.03%]
血管紧张素和内皮素转化酶的结构、进化保守性及功能
Nathalie Macours,Jeroen Poels,Korneel Hens et al.
Nathalie Macours et al.
Angiotensin-converting enzyme, a member of the M2 metalloprotease family, and endothelin-converting enzyme, a member of the M13 family, are key components in the regulation of blood pressure and electrolyte balance in mammals. From this poi...
Alberta Maria Polzonetti-Magni,Gilberto Mosconi,Laura Soverchia et al.
Alberta Maria Polzonetti-Magni et al.
The comparative approach on how and when vitellogenesis occurs in the diverse reproductive strategies displayed by aquatic and terrestrial lower vertebrates is presented in this chapter; moreover, attention has been paid to the multihormona...
Visualization of molecular activities inside living cells with fluorescent labels [0.03%]
利用荧光标记在活细胞内可视化分子活性
Gertrude Bunt,Fred S Wouters
Gertrude Bunt
The major task of modern cell biology is to identify the function and relation of the many different gene products, discovered by genomics and proteomics approaches, in the context of the living cell. To achieve this goal, an increasing too...
José A Vega,Olivia García-Suárez,Antonino Germanà
José A Vega
An immunomodulary role has been proposed for growth factors included in the family of neurotrophins. This is supported by the presence of both neurotrophins and neurotrophin receptors in the immune organs and some immunocompetent cells, the...
Victor A Chepurnov,David G Mann,Koen Sabbe et al.
Victor A Chepurnov et al.
The diatoms are the most speciose group of algae, having global ecological significance in the carbon and silicon cycles. They are almost unique among algae in being diplontic, and sexual reproduction is an obligate stage in the life cycle ...
Vidosava B Djordjević
Vidosava B Djordjević
In aerobic cells, free radicals are constantly produced mostly as reactive oxygen species. Once produced, free radicals are removed by antioxidant defenses including enzyme catalase, glutathione peroxidase, and superoxide dismutase. Reactiv...
Jean-Pierre Dadoune,Jean-Pierre Siffroi,Marie-Françoise Alfonsi
Jean-Pierre Dadoune
Major modifications in chromatin organization occur in spermatid nuclei, resulting in a high degree of DNA packaging within the spermatozoon head. However, before arrest of transcription during midspermiogenesis, high levels of mRNA are fou...
Electrophysiological approaches to the study of protein translocation in mitochondria [0.03%]
电生理学在蛋白质线粒体转运研究中的应用
Sergey M Grigoriev,Concepción Muro,Laurent M Dejean et al.
Sergey M Grigoriev et al.
Electrophysiological techniques have been integral to our understanding of protein translocation across various membranes, and, in particular, the mitochondrial inner and outer membranes. Descriptions of various methodologies (for example, ...
Functions of myc:max in the control of cell proliferation and tumorigenesis [0.03%]
Myc:max在调控细胞增殖和肿瘤发生方面的作用机制研究
Peter J Hurlin,Shala Dezfouli
Peter J Hurlin
Deregulation and elevated expression of members of the Myc family of bHLHZip transcription factors are observed in a high percentage of tumors. This close association with human cancers has led to a tremendous effort to define their biologi...
The centrosome in higher organisms: structure, composition, and duplication [0.03%]
高级生物的中心体：结构、组成和复制
Young Ou,J B Rattner
Young Ou
The centrosome found in higher organisms is an organelle with a complex and dynamic architecture and composition. This organelle not only functions as a microtubule-organizing center, but also is integrated with or impacts a number of cellu...