Mark I Mosevitsky
Mark I Mosevitsky
Mechanisms of growth cone pathfinding in the course of neuronal net formation as well as mechanisms of learning and memory have been under intense investigation for the past 20 years, but many aspects of these phenomena remain unresolved an...
Interactions between virus proteins and host cell membranes during the viral life cycle [0.03%]
病毒生命周期中病毒蛋白与宿主细胞膜的相互作用
Rodrigo A Villanueva,Yves Rouillé,Jean Dubuisson
Rodrigo A Villanueva
The structure and function of cells are critically dependent on membranes, which not only separate the interior of the cell from its environment but also define the internal compartments. It is therefore not surprising that the major steps ...
Plasticity of nonapeptidergic neurosecretory cells in fish hypothalamus and neurohypophysis [0.03%]
鱼类下丘脑和神经垂体中非九肽神经分泌细胞的可塑性
Pavel Evgenyevich Garlov
Pavel Evgenyevich Garlov
The structure and function of nonapeptidergic neurosecretory cells (NP-NSC) are considered in terms of comparative morphology. Among NSC of different ergicity for NP-NSC the most characteristic involve massive accumulation and storage of ne...
Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57 [0.03%]
内质网分子伴侣钙网蛋白、钙连蛋白和ERp57的细胞功能
Karen Bedard,Eva Szabo,Marek Michalak et al.
Karen Bedard et al.
Glycosylated proteins destined for the cell surface or to be secreted from the cell are trafficked through the endoplasmic reticulum during synthesis and folding. Correct folding is determined in large part by the sequence of the protein, b...
Michael H Hsieh,Hiep T Nguyen
Michael H Hsieh
In all biological systems, a balance between cell proliferation/growth and death is required for normal development as well as for adaptation to a changing environment. To affect their fate, it is essential for cells to integrate signals fr...
Transforming growth factor-beta (TGF-beta) and programmed cell death in the vertebrate retina [0.03%]
转化生长因子-β（TGF-β）与脊椎动物视网膜的细胞程序性死亡
Nicole Duenker
Nicole Duenker
Programmed cell death (PCD) is a precisely regulated phenomenon essential for the homeostasis of multicellular organisms. Developmental systems, particularly the nervous system, have provided key observations supporting the physiological ro...
Alan Wells,Anna Huttenlocher,Douglas A Lauffenburger
Alan Wells
Cell adhesion and its role during cell spreading and motility are central to normal development and homeostasis, including its effects on immune response and wound repair and tissue regeneration. Disruption of cell adhesion impacts not only...
Anthony D Person,Scott E Klewer,Raymond B Runyan
Anthony D Person
The valves of the heart develop in the embryo from precursor structures called endocardial cushions. After cardiac looping, endocardial cushion swellings form and become populated by valve precursor cells formed by an epithelial-mesenchymal...
Antony W Wood,Cunming Duan,Howard A Bern
Antony W Wood
The insulin-like growth factor (IGF) system plays a central role in the neuroendocrine regulation of growth in all vertebrates. Evidence from studies in a variety of vertebrate species suggest that this growth factor complex, composed of li...
Bonnie Reinhart,J Richard Chaillet
Bonnie Reinhart
This review explores the features of imprinted loci that have been uncovered by genetic experiments in the mouse. Imprinted genes are expressed from one parental allele and often contain parent-specific differences in DNA methylation within...