Patch-clamp analysis of the "new permeability pathways" in malaria-infected erythrocytes [0.03%]
疟疾病变红细胞中“新渗透途径”的膜片钳分析
Stephan M Huber,Christophe Duranton,Florian Lang
Stephan M Huber
The intraerythrocytic amplification of the malaria parasite Plasmodium falciparum induces new pathways of solute permeability in the host cell's membrane. These pathways play a pivotal role in parasite development by supplying the parasite ...
The palladin/myotilin/myopalladin family of actin-associated scaffolds [0.03%]
与肌动蛋白相关的垫蛋白/肌节蛋白/肌动蛋白垫蛋白支架家族
Carol A Otey,Andrew Rachlin,Monica Moza et al.
Carol A Otey et al.
The dynamic remodeling of the actin cytoskeleton plays a critical role in cellular morphogenesis and cell motility. Actin-associated scaffolds are key to this process, as they recruit cohorts of actin-binding proteins and associated signali...
Redundancy of biological regulation as the basis of emergence of multidrug resistance [0.03%]
生物调控的冗余性是多重耐药性产生的重要原因
Alexander A Shtil,Janeen Azare
Alexander A Shtil
Active efflux of xenobiotics is a major mechanism of cell adaptation to environmental stress. The ATP-dependent transmembrane transporter P-glycoprotein (Pgp) confers long-term cell survival in the presence of different toxins, including an...
Yasuo Maeda
Yasuo Maeda
In general, growth and differentiation are mutually exclusive, but they are cooperatively regulated during the course of development. Thus, the process of a cell's transition from growth to differentiation is of general importance not only ...
The flagellum of trypanosomes [0.03%]
锥虫的鞭毛体
Linda Kohl,Philippe Bastin
Linda Kohl
Eukaryotic cilia and flagella are cytoskeletal organelles that are remarkably conserved from protists to mammals. Their basic unit is the axoneme, a well-defined cylindrical structure composed of microtubules and up to 250 associated protei...
Mark van der Giezen,Jorge Tovar,C Graham Clark
Mark van der Giezen
The mitochondrion is generally considered to be a defining feature of eukaryotic cells, yet most anaerobic eukaryotes lack this organelle. Many of these were previously thought to derive from eukaryotes that diverged prior to acquisition of...
Erik J Suuronen,Heather Sheardown,Kimberley D Newman et al.
Erik J Suuronen et al.
Tissue-engineering techniques are being used to build in vitro models of organs as substitutes for human donor organs for transplantation as well as in vitro toxicology testing (as alternatives to use of animals). Tissue engineering involve...
Iris Meier
Iris Meier
In a eukaryotic cell, the nuclear envelope (NE) separates genetic information from the environment of biosynthesis and metabolism. Transfer of macromolecules across the NE involves the nuclear pores--large multisubunit protein complexes--an...
Maintenance of Golgi apparatus structure in the face of continuous protein recycling to the endoplasmic reticulum: making ends meet [0.03%]
面对蛋白质不断回胞内质网的情况，高尔基体如何维持自身结构：何去何从
Brian Storrie
Brian Storrie
I focus here on the Golgi apparatus and the dynamic relationship between the Golgi apparatus, the central organelle of the secretory pathway, and the endoplasmic reticulum (ER). The proteins and lipids of the Golgi apparatus originate in th...
Plastid RNA polymerases, promoters, and transcription regulators in higher plants [0.03%]
高等植物的质体RNA聚合酶、启动子和转录调节因子
Takashi Shiina,Yuichi Tsunoyama,Yoichi Nakahira et al.
Takashi Shiina et al.
Plastids are semiautonomous plant organelles exhibiting their own transcription-translation systems that originated from a cyanobacteria-related endosymbiotic prokaryote. As a consequence of massive gene transfer to nuclei and gene disappea...