Significance of the plasma membrane H+-ATPase and V-ATPase for growth and pathogenicity in pathogenic fungi [0.03%]
致病性真菌生长和致病性的质膜H+-ATP酶和V-型ATP酶的意义
S Z Yang,L T Peng
S Z Yang
Pathogenic fungi are widespread and cause a variety of diseases in human beings and other organisms. At present, limited classes of antifungal agents are available to treat invasive fungal diseases. With the wide use of the commercial antif...
From methane to value-added bioproducts: microbial metabolism, enzymes, and metabolic engineering [0.03%]
从甲烷到高附加值生物产品的微生物代谢、酶和代谢工程
Caihong Weng,Xiaowei Peng,Yejun Han
Caihong Weng
Methane is abundant in nature, and excessive emissions will cause the greenhouse effect. Methane is also an ideal carbon and energy feedstock for biosynthesis. In the review, the microorganisms, metabolism, and enzymes for methane utilizati...
Promoters and introns as key drivers for enhanced gene expression in Saccharomyces cerevisiae [0.03%]
启动子和内含子作为Saccharomyces cerevisiae 基因表达增强的关键驱动因素
Marthinus Wessel Myburgh,Kirstie Susan Schwerdtfeger,Rosemary Anne Cripwell et al.
Marthinus Wessel Myburgh et al.
The transcription of genes in the yeast Saccharomyces cerevisiae is governed by multiple layers of regulatory elements and proteins, cooperating to ensure optimum expression of the final protein product based on the cellular requirements. P...
Fundamentals of utilizing microbes in advanced cancer therapeutics: current understanding and potential applications [0.03%]
利用微生物进行先进癌症治疗的基本原理：当前理解与潜在应用
Tashmeen Kaur,Deepika Sharma
Tashmeen Kaur
One of the biggest health related issues in the twenty-first century is cancer. The current therapeutic platforms have not advanced enough to keep up with the number of rising cases. The traditional therapeutic approaches frequently fail to...
Metagenomic next generation sequencing for studying antibiotic resistance genes in the environment [0.03%]
基于下一代测序的宏基因组学在环境抗生素抗性基因研究中的应用
Bo Li,Tao Yan
Bo Li
Bacterial antimicrobial resistance (AMR) is a persisting and growing threat to human health. Characterization of antibiotic resistance genes (ARGs) in the environment is important to understand and control ARG-associated microbial risks. Nu...
Rhodotorula sp. as a cell factory for production of valuable biomolecules [0.03%]
球红假胞菌作为生产有价值的生物分子的细胞工厂
Cassamo U Mussagy,Helena F Ribeiro,Jorge F B Pereira
Cassamo U Mussagy
Rhodotorula sp. are well-known for their ability to biosynthesize a diverse range of valuable biomolecules, including carotenoids, lipids, enzymes, and polysaccharides. Despite the high number of studies conducted using Rhodotorula sp. at t...
Single-cell transcriptomics and data analyses for prokaryotes-Past, present and future concepts [0.03%]
原核生物单细胞转录组及数据分析过去、现在与未来概念
Julia M Münch,Morgan S Sobol,Benedikt Brors et al.
Julia M Münch et al.
Transcriptomics, or more specifically mRNA sequencing, is a powerful tool to study gene expression at the single-cell level (scRNA-seq) which enables new insights into a plethora of biological processes. While methods for single-cell RNA-se...
BioMateriOME: to understand microbe-material interactions within sustainable, living architectures [0.03%]
生物材料组学：在可持续的活体建筑内部理解微生物与材料间的相互作用
Beatriz Delgado Corrales,Romy Kaiser,Paula Nerlich et al.
Beatriz Delgado Corrales et al.
BioMateriOME evolved from a prototyping process which was informed from discussions between a team of designers, architects and microbiologists, when considering constructing with biomaterials or human cohabitation with novel living materia...
Biofilm ecology associated with dental caries: understanding of microbial interactions in oral communities leads to development of therapeutic strategies targeting cariogenic biofilms [0.03%]
与龋齿相关的牙菌斑生态：口腔微生物群相互作用的研究促进了抗致龋菌斑治疗策略的发展
Jian-Na Cai,Dongyeop Kim
Jian-Na Cai
A biofilm is a sessile community characterized by cells attached to the surface and organized into a complex structural arrangement. Dental caries is a biofilm-dependent oral disease caused by infection with cariogenic pathogens, such as St...
Metabolic engineering of Escherichia coli for efficient production of l-arginine [0.03%]
用于高效生产L-精氨酸的大肠杆菌代谢工程菌株的构建
Wang Hai-De,Liu Shuai,Wang Bing-Bing et al.
Wang Hai-De et al.
As a semi-essential amino acid, l-arginine (l-Arg) plays an important role in food, health care, and medical treatment. At present, the main method of producing l-Arg is the use of microbial fermentation. Therefore, the selection and breedi...