Attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage by the bronchodilator KMUP-3 [0.03%]
一种支气管扩张剂KMUP-3对实验性蛛网膜下腔出血后脑血管痉挛的改善作用
William Winardi,Chih-Jen Wang,Chih-Lung Lin et al.
William Winardi et al.
Delayed cerebral vasospasm is a main cause of morbidity and mortality as well as poor outcome in patients following aneurysmal subarachnoid hemorrhage (SAH). In this study, the effect of the bronchodilator KMUP-3 (7-[2-[4-(4-nitrobenzene)pi...
Inflammation in subarachnoid hemorrhage and delayed deterioration associated with vasospasm: a review [0.03%]
蛛网膜下腔出血及其继发血管痉挛引起恶化病情中的炎症反应综述
J Javier Provencio
J Javier Provencio
Delayed deterioration associated with vasospasm (DDAV) after subarachnoid hemorrhage (SAH), (often called vasospasm) continues to be both a difficult entity to treat and a leading cause of morbidity in patients. Until recently, attention wa...
Relevance of animal models of subarachnoid hemorrhage for examining neurobehavioral changes [0.03%]
动物亚急性和慢性蛛网膜下腔出血模型在评估神经行为改变方面的相关性研究
Ryszard M Pluta,Boris Skopets,Jerald D Kralik
Ryszard M Pluta
Background and purpose: For many years survival and neurological functionality of patients were the main outcome measures after treatment of intracranial aneurysms. But, the variable outcomes of patients operated on in a ...
Role of platelet-derived growth factor in cerebral vasospasm after subarachnoid hemorrhage in rats [0.03%]
血小板源性生长因子在蛛网膜下腔出血家兔脑血管痉挛中作用的研究
Masato Shiba,Hidenori Suzuki,Masashi Fujimoto et al.
Masato Shiba et al.
Background and purpose: The role of platelet-derived growth factor (PDGF) remains unknown in cerebral vasospasm after subarachnoid hemorrhage (SAH). In this study, we examined the effects of PDGF receptor (PDGFR) inactiva...
Matricellular protein: a new player in cerebral vasospasm following subarachnoid hemorrhage [0.03%]
基底膜蛋白：颅内动脉瘤性蛛网膜下腔出血后脑血管痉挛的新参与者
Hidenori Suzuki,Masato Shiba,Masashi Fujimoto et al.
Hidenori Suzuki et al.
Introduction: Matricellular protein (MCP) is a class of nonstructural and secreted extracellular matrix proteins that exert diverse functions, but its role in vascular smooth muscle contraction has not been investigated. ...
The roles of early brain injury in cerebral vasospasm following subarachnoid hemorrhage: from clinical and scientific aspects [0.03%]
早期脑损伤在蛛网膜下腔出血后脑血管痉挛中的作用：临床和科学角度分析
Shigeru Nishizawa
Shigeru Nishizawa
Cerebral vasospasm research has been focused on investigating the mechanisms of prolonged delayed vasoconstriction of cerebral arteries following subarachnoid hemorrhage (SAH). However, it has been clarified that induction of significant va...
Fatima A Sehba,Victor Friedrich
Fatima A Sehba
Most subarachnoid hemorrhage (SAH) patients exhibit clinical signs of cerebral ischemia at admission but no angiographic vasospasm. Consequently, the source of early cerebral ischemia is not understood. Parenchymal microvessels may contribu...
Cerebral hemodynamic and metabolic effects of remote ischemic preconditioning in patients with subarachnoid hemorrhage [0.03%]
远程缺血预处理对动脉瘤性蛛网膜下腔出血患者脑血流和代谢的影响
Nestor R Gonzalez,Robert Hamilton,Arzu Bilgin-Freiert et al.
Nestor R Gonzalez et al.
Background: Remote ischemic preconditioning (RIPC) is a form of endogenous neuroprotection induced by transient, subcritical ischemia in a distant tissue. RIPC effects on cerebral hemodynamics and metabolism have not been...
Mechanisms of microthrombosis and microcirculatory constriction after experimental subarachnoid hemorrhage [0.03%]
实验性蛛网膜下腔出血后的微血栓形成和微循环收缩机制
Mohammed Sabri,Jinglu Ai,Katarina Lakovic et al.
Mohammed Sabri et al.
Microcirculatory dysfunction may contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). This study investigated structural changes in microvessels and their relationship to brain injury after SAH. We used 15 mice (n = ...
SAH-induced suppression of voltage-gated K(+) (K (V)) channel currents in parenchymal arteriolar myocytes involves activation of the HB-EGF/EGFR pathway [0.03%]
血管生成细胞器动脉肌细胞中，活动电压门控钾(Kv)通道电流涉及HB-EGF / EGFR通路的激活
Masayo Koide,George C Wellman
Masayo Koide
Potassium channels play an important role in the regulation of arterial tone, and decreased activity of these ion channels has been linked to pial artery vasospasm after subarachnoid hemorrhage (SAH). Our previous work has shown that acute ...