Generation of congenic mouse strains by introducing the virus-resistant genes, Mx1 and Oas1b, of feral mouse-derived inbred strain MSM/Ms into the common strain C57BL/6J [0.03%]
将野外分离的耐病毒近交系MSM/Ms品系的MX1和OAS1B导入常用近交系C57BL/6J中培育遗传背景相同的携带不同基因的小鼠品系的研究
Kanako Moritoh,Hideto Yamauchi,Atsushi Asano et al.
Kanako Moritoh et al.
Mx1 (Myxovirus resistance protein) and Oaslb (Oligoadenylate synthetase-1), induced by type 1 interferon (IFN), play a role in early antiviral innate immunity by inhibiting the replication of viruses. In mice, Mx1 and Oas1b confer resistanc...
Change in body weight of mothers and neonates and in milk composition during denning period in captive Japanese black bears (Ursus thibetanus japonicus) [0.03%]
圈养亚洲黑熊(Ursus thibetanus)母体和幼体在冬眠期体重变化及乳汁组成的变化
Ruriko Iibuchi,Noriko Nakano,Tadashi Nakamura et al.
Ruriko Iibuchi et al.
Japanese black bears, Ursus thibetanus japonicus, have been classified as a vulnerable species so that data on reproduction are needed to maintain and/or extend their population. They are known to have a peculiar style of reproduction, givi...
Strain differences of cerebral ventricles in mice: can the MRL/MpJ mouse be a model for hydrocephalus? [0.03%]
小鼠脑室的品系差异：MRL/mpj 小鼠可以作为脑积水模型吗？
Keisuke Hino,Saori Otsuka,Osamu Ichii et al.
Keisuke Hino et al.
Hydrocephalus is an intractable disease characterized by the excessive accumulation of cerebrospinal fluid (CSF) in the cerebral ventricles. There are many cases in both human and animals; however, the cause and mechanism of it's developmen...
Evaluation of the potency, optimal antigen level and lasting immunity of inactivated avian influenza vaccine prepared from H5N1 virus [0.03%]
评估由H5N1病毒制备的灭活禽流感疫苗的有效性、最佳抗原水平和持久免疫力
Takashi Sasaki,Norikazu Isoda,Kosuke Soda et al.
Takashi Sasaki et al.
Test vaccines comprised of inactivated water-in-oil emulsions containing various antigen levels were prepared using a non-pathogenic H5N1 avian influenza (AI) virus, Alduck/Hokkaidol Vac-1/04 (H5N1). The potencies of these test vaccines wer...
Yoko Hara,Yuji Sunden,Kenji Ochiai et al.
Yoko Hara et al.
Rabies virus (RV) is highly neurotropic and migrates to the neuronal soma by retrograde axonal transport from nerve terminals, after which it is taken by anterograde axonal transport to be finally released into the central nervous system (C...
Sanjay Kumar,Rajender Kumar,Chihiro Sugimoto
Sanjay Kumar
The donkey population has remained unchanged in the last two decades despite a decrease in the overall population of equids, emphasizing the usefulness of the donkey as a draught and pack animal. Piroplasmosis in donkeys, caused by Theileri...
Genetic and antigenic analyses of a Puumala virus isolate as a potential vaccine strain [0.03%]
基因和抗原分析建立一种Puumala病毒分离株作为潜在疫苗株
Nur Hardy Abu Daude,Hiroaki Kariwa,Evgeniy Tkachenko et al.
Nur Hardy Abu Daude et al.
Puumala virus (PUUV), a causative agent of hemorrhagic fever with renal syndrome (HFRS), is prevalent in Europe and European Russia. No vaccine has been developed for PUUV-associated HFRS, primarily because of the low viral yield in culture...
Immunohistochemical localization of the estrogen receptor alpha (ERalpha) and progesterone receptor (PR) in the uterus of sika deer (Cervus nippon) during pregnancy [0.03%]
妊娠梅花鹿(Cervusnippon)子宫类固醇激素受体雌激素受体α和孕酮受器的免疫组化定位研究
Yojiro Yanagawa,Yukiko Matsuura,Masatsugu Suzuki et al.
Yojiro Yanagawa et al.
Information on steroid hormone receptor distribution in the uterus is essential to understand the roles of their ligands in pregnancy. This study examined the spatio-temporal localization of estrogen receptor alpha (ERalpha) and progesteron...
Polymorphism in MRL and AKR mice Sry: a candidate gene for the appearance of testicular oocyte [0.03%]
MRL和AKR小鼠Sry基因的多态性：与睾丸生卵现象相关的候选基因研究
Saori Otsuka,Akihiro Konno,Yoshiharu Hashimoto et al.
Saori Otsuka et al.
Although mammals produce either sperm or eggs depending on their sex, newborn MRL/MpJ male mice contain oocytes within their testes. In our previous study, the testicular oocyte appears as early as day 0 afterbirth and has morphological cha...
Protection by Nigella sativa against carbon tetrachloride-induced downregulation of hepatic cytochrome P450 isozymes in rats [0.03%]
Nigella sativa对四氯化碳所致大鼠肝细胞色素P450异构酶下调的保护作用
Zein S Ibrahim,Mayumi Ishizuka,Mohamed Soliman et al.
Zein S Ibrahim et al.
Nigella sativa (family Ranunculaceae) is an annual plant that has been traditionally used on the Indian subcontinent and in Middle Eastern countries. In this study, we investigated the effect of N. sativa oil on the drug-metabolizing cytoch...