BENIGN AND PATHOLOGICAL GAIN OR LOSS OF GENETIC MATERIAL — ABOUT MICROSCOPIC AND SUBMICROSCOPIC COPY NUMBER VARIATIONS (CNVs) IN HUMAN GENETICS [0.03%]
人类遗传学中的良性与病理性的基因物质的获得或丢失——关于微观和亚微观拷贝数变异(CNVS)
T Liehr
T Liehr
Submicroscopic gains or losses of chromosomal material are known as copy number variations (CNVs). Such CNVs are either connected with a disease or can also be (much more frequently) just a manifestation of human’s genetic range of variati...
I I Gin (Ermakova),E A Luttseva (Vershevskaya),I V Voronkina
I I Gin (Ermakova)
Development of hyaluronic acid (HA) supplemented biomaterials for regenerative medicine is complicated with easy water solubility of HA. It results in decreased stability of HA-based scaffolds that, consequently, initiated search for crossl...
BIORESORBABLE PROPERTIES OF CHITOSAN FIBERS IN ENDOMYSIUM AND PERIMYSIUM MUSCLE TISSUE [0.03%]
壳多糖纤维在肌内膜和肌外模肌肉组织中的生物降解性
I P Dobrovolskaya,P V Popryaduhin,V E Yudin et al.
I P Dobrovolskaya et al.
Scanning electron microscopy and histologic analysis were used in the comparative in vivo study of resorption of chitosan fibers implanted into endomysium and perimysium of a rat latissimus dorsi muscle. It was demonstrated that the mechani...
THE KARYOSPHERE CAPSULE IN OOCYTES OF HIBERNATING FROGS RANA TEMPORARIA CONTAINS ACTIN, LAMINS AND SMALL NUCLEAR RNP [0.03%]
冬眠蛙Rana temporarium卵母细胞中的karyosphere小体包含肌动蛋白、核纤层蛋白和小核snrnp
N V Ilicheva,D Yu Kiryushina,A V Baskakov et al.
N V Ilicheva et al.
The nuclei of late vitellogenic oocytes of hibernating frogs Rana temporaria were studied. During the studied period of oogenesis, chromosomes are significantly inactivated and surrounded by a fibrillar karyosphere capsule. Formation of the...
FLUORESCENT MICROSCOPY IDENTIFICATION OF THE EXPRESSION OF a2 AND b1 NA +/K+-ATPase, a1S (L-TYPE), ÑÀ2+-CHANNEL, SERCA 1/2/3 CA2+-ATPase SUBUNITS AT FAST AND SLOW MUSCLES IN THE HYPOGRAVITY MODELING EXPERIMENTS IN RATS [0.03%]
利用荧光显微镜鉴定反式作用素 a2 和 b1 NA+/K+ - ATP 阿尔法 1S( L-型)、 ÑÀ 2+ -通道, SERCA 1/2/3 CA 2+ -ATP 反式作用素亚单位在模拟失重的大鼠快速和慢速肌肉中的表达
L F Nurullin,O V Tyapkina,E M Volkov
L F Nurullin
The experiments of modeling hypogravity using fluorescent microscopy have shown a decrease of expression of b1 of Na +/K+-ATPase and Ca2+-ATPase subunits and the increase in the insensitivity of synthesis of a1S subunit of the L-type Ca2+-c...
REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) PRODUCTION BY MOUSE THYMIC EPITHELIAL CELL LINES [0.03%]
调节小鼠胸导管上皮细胞系血管内皮生长因子(VEGF)的产生
K V Rutto,I V Lyamina,I V Kudryavtsev et al.
K V Rutto et al.
Vascular endothelial growth factor (VEGF) is synthesized in small amounts by thymus epithelial cells in adults and plays a role in supporting vascular homeostasis. However its role becomes dramatically important during the process of thymus...
ROLE OF P38 MAP-KINASE IN THE STRESS-INDUCED SENESCENCE PROGRESSION OF HUMAN ENDOMETRIUM-DERIVED MESENCHYMAL STEM CELLS [0.03%]
P38丝裂原活化蛋白激酶在应激诱导的人子宫内膜源性间充质干细胞衰老进程中的作用研究
A V Borodkina,A N Shatrova,N N Nikolsky et al.
A V Borodkina et al.
Our recent findings clearly demonstrate that human endometrium-derived mesenchymal stem cells (hMESCs) respond to the sublethal oxidative stress by the premature senescence induction via ÀÒÌ/Chk2/p53/ p21/Rb pathway. Furthermore, based o...
ENDOPLASMIC RETICULUM STRESS IN DIABETIC RETINOPATHY AND THE APPROACHES TO ITS CORRECTION [0.03%]
糖尿病视网膜病变中的内质网应激及其纠正方法
A O Shpakov,Yu R Ryzhov
A O Shpakov
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM). Among the molecular mechanisms leading to the development of DR, the endoplasmic reticulum (ER) stress that is identified in DM in retinal neurons ...
FACTORS GOVERNING THE PATTERN OF SPINDLE MICROTUBULE REGROWTH AFTER TUBULIN DEPOLYMERIZATION [0.03%]
去多聚后微管蛋白再聚合决定纺锤体微管形态的机制研究
G A Pavlova,Yu A Galimova,Yu V Popova et al.
G A Pavlova et al.
We analyzed the pattern of spindle microtubule (MT) regrowth after cold- or colcemid-induced MT depolymerization in Drosophila S2 cells. Cold-induced MT disassembly at low temperature (–2 °C) destroyed kinetochore-driven MT regrowth witho...
CHARACTERIZATION OF CENTROMERIC HISTONE H3 VARIANTS IN ALLOPOLYPLOIDS OF WHEAT AND RYE [0.03%]
异源多倍体小麦和黑麦染色体组特异性CENH3表征
Yu A Lipikhina,E V Evtushenko,S S Gatskaya et al.
Yu A Lipikhina et al.
Chromosome elimination of one parental species in hybrid cell observed even after successful fertilization is one of a common phenomenon and the main problems of remote hybridization. Centromeres regulate the process of faithful segregation...