[A clinical case of erythromelalgia in a patient comorbid with antiphospholipid syndrome] [0.03%]
[抗磷脂综合征合并红斑肢痛症1例]
A A Kudrjavtseva,A V Meladze,E S Trapeznikova et al.
A A Kudrjavtseva et al.
The article presents a clinical case of secondary erythromelalgia in a comorbid patient with antiphospholipid syndrome, accompanied by burning pain, hyperemia and swelling of the lower extremities. A comprehensive examination involving a ne...
[Safety, tolerability, and pharmacokinetics of verenafusp alfa in healthy volunteers: results of an open-label multicohort phase I study] [0.03%]
关于verenafusp alfa在健康志愿者中的安全性、耐受性和药代动力学：一项开放标签多队列1期研究的结果
E A Smolyarchuk,S S Sologova,A V Bushmanova et al.
E A Smolyarchuk et al.
Background: Enzyme replacement drugs for treatment of mucopolysaccharidosis type II (MPS II) do not penetrate the blood-brain barrier, significantly reducing their efficacy in patients with neuropathic form. Verenafusp al...
[Time to achieve target lipid metabolism parameters and its impact on long-term outcomes after acute coronary syndrome in conditions of multicomponent lipid-lowering therapy] [0.03%]
急性冠脉综合征患者多药联合降脂治疗达标时间及其对长期预后的影响
A A Nekrasov,E S Timoshchenko,S G Erofeeva et al.
A A Nekrasov et al.
Aim: To evaluate the effect of the initiation time of lipid-lowering therapy (LLT) with the use of the proprotein convertase subtilisin/kexin type 9 (iPCSK9) inhibitor alirocumab on the incidence of adverse outcomes durin...
[Effect of sodium-glucose cotransporter type 2 inhibitors on the course of heart failure in patients with amyloid cardiomyopathy: Results of a pilot single-center randomized trial] [0.03%]
钠-葡萄糖共转运体类型2抑制剂对轻链型心淀粉样变性患者心力衰竭进程的影响：一项单中心随机试验的结果
A A Shoshina,S N Nasonova,I V Zhirov et al.
A A Shoshina et al.
Aim: To evaluate the efficacy and safety of the use of sodium-glucose cotransporter type 2 (SGLT-2) inhibitors in patients with chronic heart failure (CHF) due to amyloid cardiomyopathy (ACM). ...
Randomized Controlled Trial
Terapevticheskii arkhiv. 2026 Feb 14;97(12):994-1002. DOI:10.26442/00403660.2025.12.203510 2026
A A Goncharov,V A Isakov,I V Maev
A A Goncharov
Background: Recent classification of steatotic liver disorders was published in 2023, where a new form - cryptogenic steatotic liver disease (CSLD) was introduced. ...
[Dynamics of mortality from causes directly attributable to alcohol and their contribution to all-cause mortality in the Russian Federation] [0.03%]
[俄罗斯联邦直接归因于酒精的死亡率及其对总死亡率的影响的动态变化]
E M Osmanov,V A Reshetnikov,T M Akaev et al.
E M Osmanov et al.
Background: High level of alcohol consumption is one of the significant problems not only of public health, but also of the state as a whole. Aim: ...
[Predictors of ineffective therapy in patients with rheumatoid arthritis requiring bDMARDs/JAKi switching: data from a single-center prospective study] [0.03%]
【预测 rheumatoid arthritis 患者换用 bDMARDs/JAKi 失效的危险因素：单中心前瞻性研究的数据分析】
A O Bobkova,A M Lila,A E Karateev
A O Bobkova
Background: In rheumatoid arthritis (RA) the treatment target of remission or low disease activity is achieved in only 50-60% of patients, even with the use of modern targeted therapies, such as biological disease-modifyi...
A А Safiullina,A A Petrukhina,Y F Osmolovskaya et al.
A А Safiullina et al.
Idiopathic recurrent pericarditis (IRP) is an orphan inflammatory disease of the pericardium, characterised by the absence of pathognomonic symptoms and specific biomarkers. The diagnosis is complicated by the absence of characteristic clin...
S Y Milovanova,L V Lysenko,L Y Milovanova et al.
S Y Milovanova et al.
The article presents the main stages of studying cryoglobulinemia and the associated clinical symptom complex as a manifestation of cryoglobulinemic vasculitis. Achievements in the study of hepatitis C virus are shown: the etiological role ...
[Contemporary approaches to the treatment of acute respiratory viral infections and influenza. A review] [0.03%]
急性呼吸道病毒感染与流感的当代治疗方案综述
O I Trushina
O I Trushina
The article's scope is to review the modern approaches to the treatment of acute respiratory viral infections and influenza in adults, including those go higher risk. Both the main mechanisms of action of the drugs and the evidence base of ...