Generalizing trial evidence to target populations in non-nested designs: Applications to AIDS clinical trials [0.03%]
非嵌套设计中将试验证据推广至目标人群的研究:艾滋病临床试验中的应用
Fan Li,Ashley L Buchanan,Stephen R Cole
Fan Li
Comparative effectiveness evidence from randomized trials may not be directly generalizable to a target population of substantive interest when, as in most cases, trial participants are not randomly sampled from the target population. Motiv...
Shaun R Seaman,Pantelis Samartsidis,Meaghan Kall et al.
Shaun R Seaman et al.
Understanding the trajectory of the daily number of COVID-19 deaths is essential to decisions on how to respond to the pandemic, but estimating this trajectory is complicated by the delay between deaths occurring and being reported. In Engl...
Using social contact data to improve the overall effect estimate of a cluster-randomized influenza vaccination program in Senegal [0.03%]
利用社交接触数据改进塞内加尔群体随机流感疫苗接种项目的总体效果估计值
Gail E Potter,Nicole Bohme Carnegie,Jonathan D Sugimoto et al.
Gail E Potter et al.
This study estimates the overall effect of two influenza vaccination programs consecutively administered in a cluster-randomized trial in western Senegal over the course of two influenza seasons from 2009-2011. We apply cutting-edge methodo...
Transformation model based regression with dependently truncated and independently censored data [0.03%]
基于依赖截断和独立审查数据的转换模型回归
Jing Qian,Sy Han Chiou,Rebecca A Betensky
Jing Qian
Truncated survival data arise when the event time is observed only if it falls within a subject specific region. The conventional risk-set adjusted Kaplan-Meier estimator or Cox model can be used for estimation of the event time distributio...
Bayesian imputation of COVID-19 positive test counts for nowcasting under reporting lag [0.03%]
用于现在cast的新冠肺炎阳性测试计数的贝叶斯插补(报告延迟)
Radka Jersakova,James Lomax,James Hetherington et al.
Radka Jersakova et al.
Obtaining up to date information on the number of UK COVID-19 regional infections is hampered by the reporting lag in positive test results for people with COVID-19 symptoms. In the UK, for 'Pillar 2' swab tests for those showing symptoms, ...
Analysis of Networks with Missing Data with Application to the National Longitudinal Study of Adolescent Health [0.03%]
具有缺失数据的网络分析及其在青少年健康全国纵向研究中的应用
Krista J Gile,Mark S Handcock
Krista J Gile
It is common in the analysis of social network data to assume a census of the networked population of interest. Often the observations are subject to partial observation due to a known sampling or unknown missing data mechanism. However, mo...
A computationally efficient Bayesian seemingly unrelated regressions model for high-dimensional quantitative trait loci discovery [0.03%]
一种高效计算的贝叶斯似不相关回归模型用于高维度的数量性状位点发现
Leonardo Bottolo,Marco Banterle,Sylvia Richardson et al.
Leonardo Bottolo et al.
Our work is motivated by the search for metabolite quantitative trait loci (QTL) in a cohort of more than 5000 people. There are 158 metabolites measured by NMR spectroscopy in the 31-year follow-up of the Northern Finland Birth Cohort 1966...
Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects [0.03%]
具有针对自然间接效应的惩罚的贝叶斯稀疏中介分析
Yanyi Song,Xiang Zhou,Jian Kang et al.
Yanyi Song et al.
Causal mediation analysis aims to characterize an exposure's effect on an outcome and quantify the indirect effect that acts through a given mediator or a group of mediators of interest. With the increasing availability of measurements on a...
Assessing the Reproducibility of Microbiome Measurements Based on Concordance Correlation Coefficients [0.03%]
基于一致相关系数的微生物测量可重复性评估
Ying Cui,Limin Peng,Yijuan Hu et al.
Ying Cui et al.
Evaluating the reproducibility or agreement of microbiome measurements is often a crucial step to ensure rigorous downstream analyses in microbiome studies. In this paper, we address this need by developing adaptations of Lin's concordance ...
Functional data analysis and visualisation of three-dimensional surface shape [0.03%]
三维表面形状的功能数据分析和可视化
Stanislav Katina,Liberty Vittert,Adrian W Bowman
Stanislav Katina
The advent of high-resolution imaging has made data on surface shape widespread. Methods for the analysis of shape based on landmarks are well established but high-resolution data require a functional approach. The starting point is a syste...