C Wade,S Apap Mangion,J Chataway
C Wade
Neurological therapeutics are advancing rapidly, yet many neurodegenerative diseases still lack effective disease-modifying treatments, in part because traditional trial designs are ill-suited to slowly progressive, heterogeneous disorders....
Therapeutic updates in NMOSD and MOGAD: From present practice to future promise [0.03%]
NMOSD和MOGAD的治疗进展:从当前实践到未来展望
I Elosua-Bayés,A Cobo-Calvo
I Elosua-Bayés
Aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are rare, antibody-mediated inflammatory disorders of the central nervous system (CNS)....
R Marignier,M Leal Rato
R Marignier
Recently, diagnostic criteria for demyelinating diseases, including multiple sclerosis, have been updated with a focus on imaging and fluid markers. The upcoming criteria for neuromyelitis optica (NMO) introduce several clinico-radiological...
Christine Lebrun-Frenay
Christine Lebrun-Frenay
The 2024 update to the McDonald criteria for multiple sclerosis aims to be more inclusive, covering paediatric and elderly patients, as well as those with atypical symptoms or comorbidities. These criteria emphasise objective evidence of ce...
Contribution of new imaging sequences to the diagnosis of multiple sclerosis [0.03%]
新的影像序列在诊断多发性硬化症中的作用
M Moccia,S Cocozza
M Moccia
The 2024 revision of the McDonald criteria reinforces the central role of magnetic resonance imaging (MRI) in diagnosing multiple sclerosis (MS). Key updates include the addition of the optic nerve as a fifth typical region for disseminatio...
Neuroimaging confirms selective cerebral involvement in primary lateral sclerosis and predilection to brain regions with high metabolic activity [0.03%]
神经影像证实原发性侧索硬化选择性的脑部受累及高代谢区域的脑区易感性
J Kleinerova,M Tahedl,E Finegan et al.
J Kleinerova et al.
Background: Primary lateral sclerosis (PLS) is a low incidence motor neuron disease manifesting in progressive limb spasticity, gait impairment, bulbar dysfunction and often in pseudobulbar affect. Varying degree of front...
Prospective comparative study of two educational games used to teach neurological semiotics [0.03%]
两种神经病学符号教学游戏的比较研究
J Mazoyer,T Madec,S Zeidan et al.
J Mazoyer et al.
Introduction: Neurological semiology is often considered to be difficult to learn. The "Neurological hat game (NHG)" and the "Neurospeed game (NSG)" are two educational games that have both proven their effectiveness as a...
"Time is Brain" also in multiple sclerosis: Fifteen years later, a fully consolidated concept [0.03%]
"time就是brain:多发性硬化症十五年后的完全巩固概念"
A Maarouf,B Audoin,J Pelletier
A Maarouf
Balint syndrome as the initial presentation of neuromyelitis optica spectrum disorder [0.03%]
视神经脊髓炎谱系病的首发表现——Balint综合征
N Billet,S Donat,C Grosset-Janin et al.
N Billet et al.
Changing nosology, unknown epidemiology: What do we know about functional neurological disorders in the community? [0.03%]
变nosology,未知流行病学:社区中关于功能性神经障碍我们知道什么?
O Mounir Alaoui,E Roze,A Daubigney et al.
O Mounir Alaoui et al.
Objective: To estimate the epidemiology of functional neurological disorders (FND) in the general population through a systematic literature review and to assess the quality of the included studies. ...