Narratives of Undergraduate Research, Mentorship, and Teaching at UCLA [0.03%]
美国加州大学洛杉矶分校关于本科科研、导师制和教学的故事
Simone L Stevens,Alice C Phung,Alejandra Gonzalez et al.
Simone L Stevens et al.
This work describes select narratives pertaining to undergraduate teaching and mentorship at UCLA Chemistry and Biochemistry by Alex Spokoyny and his junior colleagues. Specifically, we discuss how individual undergraduate researchers contr...
Recent advances in analysis of trace elements in environmental samples by X-ray based techniques (IUPAC Technical Report) [0.03%]
X射线技术分析环境样本中痕量元素的最新进展（IUPAC技术报告）
Roberto Terzano,Melissa A Denecke,Gerald Falkenberg et al.
Roberto Terzano et al.
Trace elements analysis is a fundamental challenge in environmental sciences. Scientists measure trace elements in environmental media in order to assess the quality and safety of ecosystems and to quantify the burden of anthropogenic pollu...
María Vallet-Regí
María Vallet-Regí
Since the second half of the 20th century, bioceramics are used for bone repair and regeneration. Inspired by bones and teeth, and aimed at mimicking their structure and composition, several artificial bioceramics were developed for biomedi...
Extending the S-benzimidazolyl (SBiz) platform: N-alkylated SBiz glycosyl donors with the universal activation profile [0.03%]
扩展S-苯并咪唑(S-BIZ)平台：具有通用激活特征的N-烷基化S-BIZ糖苷供体
Scott J Hasty,Nigam P Rath,Alexei V Demchenko
Scott J Hasty
This article describes the development of alkylated S-benzimidazolyl (SBiz) imidates as versatile building blocks for chemical glycosylation. The SBiz imidates have been originally developed as a new platform for active-latent glycosylation...
Mara K O&#x;Neill,Brent F Piligian,Claire D Olson et al.
Mara K O&#x;Neill et al.
Trehalose is a non-reducing sugar whose ability to stabilize biomolecules has brought about its widespread use in biological preservation applications. Trehalose is also an essential metabolite in a number of pathogens, most significantly t...
Stereocontrolled 1- S-glycosylation and comparative binding studies of photoprobe-thiosaccharide conjugates with their O-linked analogs [0.03%]
立体选择性S-糖基化及光探针硫醇糖与相应氧连接类似物的配体结合比较研究
Lingquan Deng,Xin Wang,Suji Uppalapati et al.
Lingquan Deng et al.
The use of thioglycosides and other glycan derivatives with anomeric sulfur linkages is gaining increasing interest, both in synthesis and in various biological contexts. Herein, we demonstrate the occurrence and circumvention of anomerizat...
David G I Kingston,Lawrence Tamarkin,Giulio F Paciotti
David G I Kingston
Paclitaxel (Taxol®) is one of the most important anticancer agents developed over the last 30 years. Its primary mechanism of action is by interaction with the cellular protein tubulin, causing irreversible polymerization to microtubules. ...
Jason C Green,G Leslie Burnett th,Thomas R R Pettus
Jason C Green
Two cycloaddition strategies are described that lead to various chroman spiroketals from assorted exocyclic enol ethers. Unlike conventional thermodynamic ketalization strategies, the stereochemical outcome for this approach is determined b...
3-Acyloxy-1,4-enyne: a New Five-carbon Synthon for Rhodium-Catalyzed (5+2) Cycloadditions [0.03%]
3-酰氧基-1,4-烯炔：铑催化(5+2)环加成反应的新五碳合成子
Casi M Schienebeck,Xiaoxun Li,Xing-Zhong Shu et al.
Casi M Schienebeck et al.
Seven-membered rings are ubiquitous in natural products and pharmaceutical agents and their syntheses continue to stimulate the development of novel synthetic methods. The (5+2) cycloaddition is one of the most efficient ways to access seve...
New ligand platforms featuring boron-rich clusters as organomimetic substituents [0.03%]
含有富硼基团的配体平台作为有机模拟取代基
Alexander M Spokoyny
Alexander M Spokoyny
200 years of research with carbon-rich molecules have shaped the development of modern chemistry. Research pertaining to the chemistry of boron-rich species has historically trailed behind its more distinguished neighbor (carbon) in the per...