[Chemoprevention of breast cancer - with special interest of tamoxifen] [0.03%]
乳腺癌的化学预防——特别是他莫昔芬的研究进展
T Nagykálnai
T Nagykálnai
The adjuvant use of tamoxifen confers a survival advantage for patients with node-positive and node-negative breast cancer and demonstrated benefit when used alone or in combination with chemotherapy to treat advanced breast cancer.Tamoxife...
Olga Esik,Akos Horváth,András Bajcsay et al.
Olga Esik et al.
The long-term survival probability for Hungarian lung cancer patients is 10% worse than the best results published in the most highly developed countries (the mean 5-year survival probability in Hungary is 5%, in contrast with the 15% survi...
Review
Magyar onkologia. 2002;46(1):51-85. DOI: 2002
[Detection of n-myc gene amplification in neuroblastoma using polymerase chain reaction based methods] [0.03%]
应用聚合酶链反应技术检测神经母细胞瘤n-myc基因扩增
Zsombor Melegh,Ildikó Bálint,Kálmán Nagy et al.
Zsombor Melegh et al.
We have used semiquantitative and real-time quantitative PCRs to detect n-myc gene-amplification in 21 frozen neuroblastoma biopsies and IMR 32 cell line in order to predict biological behaviour of the tumors. Two primer pairs were used in ...
[Causal association between human papilloma virus infection and head and neck and esophageal squamous cell carcinoma] [0.03%]
人乳头瘤病毒感染与头颈和食管鳞癌的病因关联性研究进展
Zoltán Szentirmay,Imre Szántó,Ildikó Bálint et al.
Zoltán Szentirmay et al.
HPVs commonly cause proliferative lesions of squamous epithelium, and infection with certain HPV types carries a high risk of malignant transformation. We used molecular techniques to detect and type HPV in papillomas and carcinomas in the ...
[FISH diagnostics] [0.03%]
[FISH诊断]
Zoltán Sápi,Miklós Bodó
Zoltán Sápi
For over two decades banding has remained the "gold standard" of cytogenetic analysis, providing the first genome-wide screen for abnormalities. However, conventional cytogenetic banding techniques are limited to the detection of rearrangem...
Review
Magyar onkologia. 2002;46(1):25-32. DOI: 2002
Tibor Füle,Ilona Kovalszky
Tibor Füle
For many years data of cancer research indicated that viruses can cause cancer. Virus infections induce cancer by different mechanisms. To predict the significance of a viral DNA fragment in human cells we have to be aware of the changes th...
Review
Magyar onkologia. 2002;46(1):17-22. DOI: 2002
[HER-2 diagnostics] [0.03%]
[赫尔二诊断]
Agnes Bánkfalvi
Agnes Bánkfalvi
HER-2 (c-erbB2, neu) receptor is the molecular marker of ductal breast cancer although it is verexpressed in other adenocarcinoma as well (e.g.endometrial, colorectal and lung cancers). The increased receptor expression is most frequently (...
Review
Magyar onkologia. 2002;46(1):11-5. DOI: 2002
László Kopper,József Tímár
László Kopper
DNA-microarray technology can be used to assess the expression of several thousands of genes at the same time. The identification of the gene expression profiles may help to better characterize human cancer. These studies may reveal subclas...
Review
Magyar onkologia. 2002;46(1):3-9. DOI: 2002