Gábor Körösmezey,Gabriella Gyõri,Gábor Rudas et al.
Gábor Körösmezey et al.
Primary myelofibrosis has the worst outcome among classical chronic myeloproliferative neoplasms. The past decade has brought numerous discoveries elucidating the role of proliferative mutations in disease pathogenesis. Mutations of the gen...
Review
Magyar onkologia. 2017 Mar 8;61(1):47-55. DOI: 2017
[The role of driver and subclonal mutations in pathogenesis of primary myelofibrosis] [0.03%]
[驱动基因和亚克隆突变在原发性骨髓纤维化发病机制中的作用]
Réka Mózes,Ambrus Gángó,Zsófia Boha et al.
Réka Mózes et al.
Primary myelofibrosis (PMF) is a Philadelphia chromosome negative, clonal myeloproliferative neoplasm characterised by a progressive nature. Morphologically, the bone marrow biopsy shows features of abnormal proliferation of terminally diff...
Review
Magyar onkologia. 2017 Mar 8;61(1):36-45. DOI: 2017
[Acute myeloid leukaemia in adults: therapeutic possibilities today and new agents in the future] [0.03%]
成人急性髓系白血病目前的治疗选择和未来的新型药物治疗
Ilona Tárkányi
Ilona Tárkányi
Advances in the treatment of acute myeloid leukaemia are still modest. Through emerging knowledge in molecular genetics we gain new insights into the pathogenesis of the disease. The first targeted therapies have emerged, but failed to show...
Review
Magyar onkologia. 2017 Mar 8;61(1):29-35. DOI: 2017
Hajnalka Rajnai,Attila Péter Király
Hajnalka Rajnai
The recent advances in the field of molecular biology have enabled a more comprehensive genomic analysis in myeloid malignancies. The studies have unveiled recurrent somatic mutations in several genes illuminating the clinical heterogeneity...
Review
Magyar onkologia. 2017 Mar 8;61(1):21-28. DOI: 2017
Anna Orsolya Mucsi,Zsolt Nagy
Anna Orsolya Mucsi
Waldenström's macroglobulinemia is a rare, low-grade non-Hodgkin lymphoma of B cell origin, most common in elderly male patients with a median age of 64 years at diagnosis. It accounts for approximately 2% of hematologic malignancies. The ...
Review
Magyar onkologia. 2017 Mar 8;61(1):12-20. DOI: 2017
[The pathology and genetic background of lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia] [0.03%]
淋巴浆细胞淋巴瘤/瓦尔登斯特伦巨球蛋白血症的病理及遗传背景
Botond Timár
Botond Timár
Lymphoplasmacytic lymphoma is a rare low-grade B-cell lymphoma, which is composed of a mixture of small lymphocytes, plasmacytoid cells and plasma cells that typically infiltrate the bone marrow, but lymph nodes and rarely other organs can ...
Review
Magyar onkologia. 2017 Mar 8;61(1):6-11. DOI: 2017
[Oncogen dependent regulation of the migration and proliferation of human tumor cells] [0.03%]
致癌基因依赖的人肿瘤细胞迁移和增殖调节
Tamás M Garay
Tamás M Garay
The high mortality of solid tumors can be attributed to their invasive and metastatic potential that is based on their migration and proliferation. Importantly, growth factor receptor (GF) signaling pathways regulating proliferation and mig...
[Tocilizumab treatment of HHV8-positive/HIV-negative, multricentric plasma cell type Castleman's disease] [0.03%]
托珠单抗治疗HHV8阳性/HIV阴性多中心型Castleman病原发性浆细胞淋巴增生症患者
Györgyi Mûzes,Judit Csomor,Ferenc Sipos
Györgyi Mûzes
This is a case presentation of a HHV8-positive multicentric Castleman's disease (MCD) of plasma cell type. The patient failed to respond to combined immunosuppressive therapy and monoclonal anti-CD20 therapy. Interestingly, administration o...
Case Reports
Magyar onkologia. 2016 Nov 29;60(4):328-332. DOI: 2016
[Investigating the predictive value of RMI and ROMA indices in patients with ovarian tumors of uncertain dignity] [0.03%]
[探究RMI和ROMA指数在卵巢肿瘤不明确恶性程度患者中的预测价值]
Géza Krascsenits,Boglárka Balázs,Anna Dudnyikova et al.
Géza Krascsenits et al.
We were investigating the predictive value of RMI and ROMA indices in patients with ovarian tumors of uncertain dignity, in order to determine whether these methods are suitable for the early detection of ovarian malignancy. Our study inclu...
[Curative radiotherapy of early-stage lung cancer using respiratory motion compensation] [0.03%]
利用呼吸运动补偿技术进行早期肺癌根治性放疗
András Szilágyi,Tamás Pócza,Csaba Polgár et al.
András Szilágyi et al.
In this paper we present our early experience with a method for the management of respiratory motion in radiotherapy for early-stage lung cancer. Forty-six patients were irradiated with a total dose of 60 Gy. Tumor response on control CT, s...