[Studying the tumor growth inhibitory effect of modified GnRH-III-anthracycline bioconjugates in subcutaneous vs. orthotopic models in vivo] [0.03%]
修饰GnRH-III-蒽环生物缀合物体内抑瘤效果的研究:皮下模型与原位模型的比较
Bence Kapuvári,Ákos Schulcz,Rózsa Hegedüs et al.
Bence Kapuvári et al.
Targeted tumor therapy is a perspective procedure to specifically destroy the cancer tissues with eliminating or at least decreasing the side effects of anticancer drugs. For this purpose the drug molecule is attached to a targeting moiety ...
[The potential of three-dimensional tumor models and cell culturing in cancer research and diagnostics] [0.03%]
三维肿瘤模型和细胞培养在癌症研究和诊断中的潜力
Róbert Alföldi,János Gábor Szebeni,László G Puskás
Róbert Alföldi
In vitro testing of antitumor agents on human cancer cell lines has become essential in pharmaceutical research and in clinical practice. Although the most widely used technique is the two-dimensional cell growing protocol (in tissue cultur...
[Measuring 14C-glucose and 14C-acetate oxidation in tumour cells and tumorous host organism] [0.03%]
测定肿瘤细胞和携瘤宿主有机体中14C-葡萄糖及14C-醋酸的氧化状况
Zoltán Hujber,András Jeney,Júlia Oláh et al.
Zoltán Hujber et al.
Tumour cell metabolism can be influenced by alterations of the extracellular microenvironment and the tumour-promoting genetically changed mechanisms. There is increasing interest to introduce appropriate bioenergetic assays to describe the...
Janina Kulka,Anna-Mária Tõkés,Lilla Madaras et al.
Janina Kulka et al.
In the second half of the 20th century research focusing to breast carcinomas at the Semmelweis University had been mostly linked to the 2nd Department of Pathology. Nowadays, following the rapidly improving treatment modalities in breast c...
[Excerpts from the collaborative lung cancer research program of Semmelweis University, the National Institute of Oncology and Korányi Institute of TB and Pulmonology (2010-2015)] [0.03%]
[塞梅尔维斯大学、国家肿瘤研究所和肺结核及肺病科柯兰尼研究所合作进行肺癌研究计划(2010-2015)]摘录
Balázs Hegedûs,Judit Moldvay,Judit Berta et al.
Balázs Hegedûs et al.
Lung cancer places a significant socio-economic burden on the Hungarian population. This overview summarizes the findings of collaborative translational lung cancer research efforts of three Hungarian flagship academic institutions, the Sem...
[Melanoma research in Hungary: promising results in a previously orphan tumor] [0.03%]
匈牙利的黑色素瘤研究:一种以往被忽视肿瘤的治疗前景乐观
Margit Balázs,Laura Vízkeleti,Szilvia Ecsedi et al.
Margit Balázs et al.
Melanoma research has a two decade history in Hungary and is based on three groups located at the National Institute of Oncology (NIO), the University of Debrecen (DU) and Semmelweis University (SU). Previously we have summarized the achiev...
[Biological role and prognostic significance of genetic alterations in human malignant melanomas] [0.03%]
[人类恶性黑色素瘤中遗传变异的生物学作用及预后意义]
Laura Vízkeleti
Laura Vízkeleti
Metastatic process accounts for the vast majority of melanoma associated mortality, and also results in difficulties in the effective treatment. Therefore, identification of novel biomarkers could contribute to melanoma prognosis, and may a...
A Ryska,R Dziadziuszko,W Olszewski et al.
A Ryska et al.
Development of the target therapies of lung cancer was a rapid process which fundamentally changed the pathological diagnosis as well. Furthermore, molecular pathology became essential part of the routine diagnostics of lung cancer. These c...
Review
Magyar onkologia. 2015 Sep;59(3):259-66. DOI: 2015
[Fulvestrant (Faslodex®) for hormone sensitive breast cancer. A review] [0.03%]
[福沙利汀(Faslodex)治疗激素敏感性乳腺癌的疗效评价]
Tamás Nagykálnai,László Landherr,Ibolya Laczó et al.
Tamás Nagykálnai et al.
Endocrine agents are well established standards of care in hormone-sensitive postmenopausal breast cancer. The pure estrogen receptor antagonist (down-regulator) fulvestrant after binding to the ER induces its conformational change which di...
Review
Magyar onkologia. 2015 Sep;59(3):251-7. DOI: 2015
[The first 25 years of oncopsychology at the National Institute of Oncology: antecedents and events (1988-2013)] [0.03%]
国家肿瘤医院心理社会肿瘤学前25年:起源和事件(1988-2013)
Ágnes Riskó
Ágnes Riskó
The first oncopsychological department was established in National Institute of Oncology by Sándor Eckhardt in 1988. At an early stage the specialists who were interested in mental hygiene made a united effort with Katalin Muszbek's oncops...