Chun Hung Weng,Jialei Tang,Kyu Young Han
Chun Hung Weng
Line-scanning confocal microscopy provides high imaging speed and moderate optical sectioning strength, which makes it a useful tool for imaging various biospecimens ranging from living cells to fixed tissues. Conventional line-scanning sys...
Zero-Mode Waveguide Nanophotonic Structures for Single Molecule Characterization [0.03%]
零模波导纳米光子结构在单分子表征中的应用
Garrison M Crouch,Donghoon Han,Paul W Bohn
Garrison M Crouch
Single-molecule characterization has become a crucial research tool in the chemical and life sciences, but limitations, such as limited concentration range, inability to control molecular distributions in space, and intrinsic phenomena, suc...
Broadband dielectric spectroscopic detection of volatile organic compounds with ZnO nanorod gas sensors [0.03%]
宽带介电频谱法利用ZnO纳米线气体传感器检测挥发性有机化合物
Papa K Amoah,Pengtao Lin,Helmut Baumgart et al.
Papa K Amoah et al.
Metal-oxide (MO) semiconductor gas sensors based on chemical resistivity necessarily involve making electrical contacts to the sensing materials. These contacts are imperfect and introduce errors into the measurements. In this paper, we dem...
Conducting polymer nanowires for control of local protein concentration in solution [0.03%]
溶液中局部蛋白质浓度控制的导电聚合物纳米线
Joshua D Morris,Scott B Thourson,Krishna Panta et al.
Joshua D Morris et al.
Interfacing devices with cells and tissues requires new nanoscale tools that are both flexible and electrically active. We demonstrate the use of PEDOT:PSS conducting polymer nanowires for the local control of protein concentration in water...
Intraoperative hyperspectral label-free imaging: from system design to first-in-patient translation [0.03%]
术中高光谱无标记成像：从系统设计到首次临床转化
Michael Ebner,Eli Nabavi,Jonathan Shapey et al.
Michael Ebner et al.
Despite advances in intraoperative surgical imaging, reliable discrimination of critical tissue during surgery remains challenging. As a result, decisions with potentially life-changing consequences for patients are still based on the surge...
Between life and death: strategies to reduce phototoxicity in super-resolution microscopy [0.03%]
超越生命与死亡——提高超分辨显微成像光毒性的策略研究
Kalina L Tosheva,Yue Yuan,Pedro Matos Pereira et al.
Kalina L Tosheva et al.
Super-resolution microscopy (SRM) enables non-invasive, molecule-specific imaging of the internal structure and dynamics of cells with sub-diffraction limit spatial resolution. One of its major limitations is the requirement for high-intens...
Christian M Griffith,Stephanie A Huang,Crescentia Cho et al.
Christian M Griffith et al.
Mechanical forces regulate a diverse set of biological processes at cellular, tissue, and organismal length scales. Investigating the cellular and molecular mechanisms that underlie the conversion of mechanical forces to biological response...
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy [0.03%]
高光子计数率可提升超分辨率荧光闪烁谱学的质量
Falk Schneider,Pablo Hernandez-Varas,B Christoffer Lagerholm et al.
Falk Schneider et al.
Probing the diffusion of molecules has become a routine measurement across the life sciences, chemistry and physics. It provides valuable insights into reaction dynamics, oligomerisation, molecular (re-)organisation or cellular heterogeneit...
Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications [0.03%]
用于神经生物学应用的增强时间聚焦多光子显微镜的穿透深度
Christopher J Rowlands,Oliver T Bruns,Daniel Franke et al.
Christopher J Rowlands et al.
The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 µm in brain tissue. This is substantially deeper than the highest previously-re...
NanoJ: a high-performance open-source super-resolution microscopy toolbox [0.03%]
NanoJ：一款高性能的开源超分辨率显微镜工具箱
Romain F Laine,Kalina L Tosheva,Nils Gustafsson et al.
Romain F Laine et al.
Super-resolution microscopy (SRM) has become essential for the study of nanoscale biological processes. This type of imaging often requires the use of specialised image analysis tools to process a large volume of recorded data and extract q...