Nohhyeon Kwak,Mohammad Washeem,Tara N Gaire et al.
Nohhyeon Kwak et al.
Bioaerosols are critical components of the atmospheric environment, yet their accurate characterization remains challenging due to the lack of a standardized sampling methodology. In this study, we compared three commonly used bioaerosol sa...
Subject-Specific Whole-Lung CFPD Coupled with PBPK/PD to Predict Inhaled Bronchodilator Response in Asthmatic and Healthy Subjects [0.03%]
针对整体肺CFPD与PBPK / PD结合预测哮喘患者和健康受试者吸入支气管扩张剂的反应
Prathish K Rajaraman,Xuan Zhang,Alejandro P Comellas et al.
Prathish K Rajaraman et al.
Accurate prediction of bronchodilator performance remains challenging. We present a coupled computational fluid and particle dynamics (CFPD) and physiologically-based pharmacokinetic/pharmacodynamics (PBPK/PD) framework that leverages subje...
Exploratory application of DMD for particle deposition and fluid field in the respiratory tract [0.03%]
DMD在呼吸道颗粒沉积及流场中的探索性应用研究
Martin S Graffigna,Ignacio R Bartol,Mauricio E Tano et al.
Martin S Graffigna et al.
Simulating particle deposition in the respiratory tract requires high computational effort due to the intricate airway geometry and complex airflow-particle interactions. To address this challenge, this study introduces the first demonstrat...
2-Methyltetrol Sulfate Oxidation by Hydroxyl Radical in Atmospheric Water Mimics and Implications for the Fate of Isoprene-Derived Secondary Organic Aerosol [0.03%]
羟基自由基氧化模拟大气水中的异戊二烯衍生二次有机气溶胶标记物硫酸甲基四醇的研究及意义
Haley M Royer,Ashley J Harrill,Cade M Christensen et al.
Haley M Royer et al.
2-Methyltetrol sulfate diastereomers (2-MTS) form from acid-driven multiphase chemical conversion of inorganic sulfate (Sulfinorg) aerosol by isoprene-derived epoxydiols (IEPOX). Studies have explored 2-MTS sinks within aerosols, but observ...
A New Aerosol Respiratory Deposition Approach: Health Risks of Metals in Aerosols from Electronic Nicotine Delivery Systems and Heated Tobacco Products [0.03%]
一种新的气溶胶呼吸沉积方法：电子尼古丁输送系统和加热烟草产品气溶胶中金属的健康风险
Jinho Lee,Wei-Chung Su
Jinho Lee
This study employed a newly developed MALDA-MOUDI approach to investigate the respiratory deposition of Electronic Nicotine Delivery Systems (ENDS) and Heated Tobacco Products (HTP) aerosols and used the resulting data to assess associated ...
Subject-specific modeling framework for particle deposition using computational fluid dynamics [0.03%]
基于计算流体动力学的颗粒沉积学科建模框架
Ignacio R Bartol,Martin S Graffigna Palomba,Robert J Dawson et al.
Ignacio R Bartol et al.
Quantifying particle deposition and dose in the respiratory tract requires a physiologically realistic representation and reproducible computational workflows. However, existing modeling frameworks, such as the International Commission on R...
Dynamic of infectious aerosols generated by cough from patients with pulmonary tuberculosis [0.03%]
肺结核患者咳嗽产生的传染性气溶胶动力学研究
Taline Canto Tristão,Mariana Abou Mourad Ferreira,Pedro Sousa de Almeida Júnior et al.
Taline Canto Tristão et al.
Tuberculosis (TB) is an ancient disease transmitted through aerosols frequently generated by coughing and it is still unknown whether there is variability in cough aerosol output throughout the day and whether this may impact patients' infe...
Modeling aerosol bolus inhalations in the human lung with the Multiple Path Particle Deposition model: Comparison with experimental data [0.03%]
人体肺部气溶胶束吸入的多重路径粒子沉降模型：与实验数据相比较
B Asgharian,O Price,A A T Borojeni et al.
B Asgharian et al.
Existing one-dimensional (1D) models of aerosol dosimetry often ignore mixing mechanisms of inhaled aerosols during their transport in the lung. This mixing or aerosol dispersion results from different physical mechanisms in different regio...
Characterization of Pediatric Extrathoracic Aerosol Deposition with Air-Jet Dry Powder Inhalers [0.03%]
用于儿科非呼吸道给药的气流干粉吸入器的研究
Morgan L Thomas,Karl Bass,Dale Farkas et al.
Morgan L Thomas et al.
The use of air-jet dry powder inhalers (DPIs) offers a number of advantages for the administration of pharmaceutical aerosols, including the ability to achieve highly efficient and potentially targeted aerosol delivery to the lungs of child...
A high-throughput, turbulent-mixing, condensation aerosol concentrator for direct aerosol collection as a liquid suspension [0.03%]
一种用于直接收集液滴悬浮液的高通量湍流混合冷凝气溶胶浓缩器
Orthodoxia Zervaki,Dionysios D Dionysiou,Pramod Kulkarni
Orthodoxia Zervaki
Trace measurement of aerosol chemical composition in workplace atmospheres requires the development of high-throughput aerosol collectors that are compact, hand-portable, and can be operated using personal pumps. We describe the design and ...