Marisol Olivares-Arévalo,Hugo Villamil-Ramírez,Blanca López-Contreras et al.
Marisol Olivares-Arévalo et al.
Although obesity is an important risk factor for cardiometabolic diseases, not every individual with obesity shows metabolic complications, this phenotype is called metabolically healthy obesity (MHO). Several studies suggest that the distr...
Diagnosis of inborn errors of metabolism through massive DNA sequencing: benefits and limitations [0.03%]
高通量DNA测序在遗传性代谢病中的应用和局限性
Vianey Ordoñez-Labastida,Juan C Zenteno
Vianey Ordoñez-Labastida
Inborn errors of metabolism (IEM) are inherited disorders resulting from genetic defects in proteins involved in breakdown or storage of fatty acids, carbohydrates and proteins. Collectively, IEM encompasses approximately 1000 different dis...
Humberto García-Ortiz,Francisco M Barajas-Olmos,Cecilia Contreras-Cubas et al.
Humberto García-Ortiz et al.
Type 2 diabetes (T2DM) is a public health problem and the second leading cause of death in Mexico. More than 20 years after the human genome project was completed, the development of innovative technologies and methodologies to determine th...
Miguel Cruz,Jaime Berumen
Miguel Cruz
Complex relationship between Amerindian ancestry and obesity in the Mexican population [0.03%]
墨西哥人口中美洲印第安人祖先与肥胖的复杂关系
Paulina Baca,Elizabeth Barrera,Pablo A Kuri et al.
Paulina Baca et al.
The high prevalence of obesity in Mexican-American populations in the United States has suggested that the different genetic composition of the Mexican population may be related to the high prevalence of obesity in Mexico. Recently, the gen...
Contributions of pharmacogenetics to personalized precision therapy of diabetes and hypercholesterolemia [0.03%]
药理基因组学在糖尿病和高胆固醇的个性化精准治疗中的贡献
Hugo A Barrera-Saldaña,Rafael B R León-Cachón,Vanessa González-Covarrubias et al.
Hugo A Barrera-Saldaña et al.
Background: Personalized medicine allows the selection of the drug and dose based on the patient's genetic information, which is imperative in the treatment of diabetes and hypercholesterolemia, diseases with high prevale...
Rosalinda Posadas-Sánchez,Giovanny Fuentevilla-Álvarez,Gilberto Vargas-Alarcón
Rosalinda Posadas-Sánchez
Coronary artery disease (CAD) is a chronic and multifactorial disease, considered a global health problem. Environmental and genetic factors participate in its development. Various studies, including whole genome and candidate gene studies,...
Genomics of cardiometabolic disease: contributions of Mexican research groups [0.03%]
心血管代病基因组学：墨西哥研究团队的贡献
Mayra Domínguez-Pérez,Leonor Jacobo-Albavera,Samuel Canizales-Quinteros et al.
Mayra Domínguez-Pérez et al.
Understanding the genetic architecture of complex disease has helped identify at risk individuals, new pathways involved in pathophysiology, and potential pharmacological targets for prevention and/or treatment. Thus, the identification of ...
Ana Ochoa-Guzmán,María T Tusié-Luna,Erwin Chiquete et al.
Ana Ochoa-Guzmán et al.
The prevalence of metabolic diseases in Mexicans has grown in recent decades, which increases the burden on the health system. The study of the genetics of metabolic diseases is a complex process resulting from an interaction between enviro...
Arnao-Villegas Y Manuel
Arnao-Villegas Y Manuel