Pharmacokinetics of midazolam, 1´-OH-midazolam, 4-OH-midazolam, 1´-OH-midazolam-β-D-glucuronide, and 4-OH-midazolam-β-D-glucuronide in serum and urine from patients undergoing cardiac surgery [0.03%]
心脏手术患者血浆和尿液中咪达唑仑及其代谢产物的药代动力学特征研究
Mariusz Procak,Sebastian Rojek,Wojciech Jawień et al.
Mariusz Procak et al.
Background: The benzodiazepine midazolam is widely used pre- and intraoperatively in intensive care units. 1´-OH-midazolam, one of the major metabolites, is pharmacologically active. Accumulation of 1´-OH-midazolam, e.g...
Investigation of platelet-antibody interactions using ultrasound-induced chemiluminescence [0.03%]
应用超声波诱导化学发光法研究血小板抗体的相互作用
Anna Lizoń,Wiktoria Walawska,Monika Papież et al.
Anna Lizoń et al.
Background: Platelet transfusion refractoriness (PTR) presents a significant clinical challenge, often requiring specialized diagnostic and donor-matching strategies. Existing immunoassays detect anti-platelet antibodies ...
The slowing pulse: a history of research on training-induced resting bradycardia [0.03%]
渐缓的心跳:训练诱导的静息期心动过缓研究史
Marcin Grandys,Mirosław Woźniak,Jerzy A Żołądź
Marcin Grandys
Training-induced resting bradycardia is characteristic of endurance athletes, but it also often occurs in less trained, physically active people. It is commonly believed that slowing of the heart rate is a positive sign of systemic adaptati...
Premature ovarian insufficiency: decoding oxidative stress, metabolic pathways, epigenetic regulation, and the therapeutic role of yoga [0.03%]
卵巢早衰:氧化应激、代谢途径、表观遗传调控及瑜伽治疗作用的解析
Rejesh Kumar,Dibakar Borthakur,Rima Dada
Rejesh Kumar
Premature ovarian insufficiency (POI) is a heterogeneous multifactorial disorder characterized by amenorrhoea, hypoestrogenism and elevated serum gonadotropins in women below 40 years. Genetic predisposition, infections, iatrogenic, autoimm...
Therapeutic strategies in irritable bowel syndrome: current standards, emerging options and future challenges [0.03%]
肠易激综合征的治疗策略:现行标准、新兴选项及未来挑战
Wojciech Michał Janowski,Gabriela Maria Kaczmarczyk,Aleksandra Tarasiuk-Zawadzka et al.
Wojciech Michał Janowski et al.
The development of safe and efficient therapeutic interventions in irritable bowel syndrome (IBS) is challenged by the complexity of its pathophysiology and a wide range of symptoms. On the other hand, with the progress in design of diagnos...
Morphologic study on the patterns of communication between median and musculocutaneous nerves in humans [0.03%]
人正中神经与桡神经肌肉支吻合变异的解剖学研究
Dibakar Borthakur,Rima Dada,Arthi Ganapathy et al.
Dibakar Borthakur et al.
Objective: Several patterns of communication between the median nerve (MN) and the musculocutaneous nerve (MCN) have been described along with a number of classification systems. However, some atypical patterns of communi...
A case of an ALS patient with an SQSTM1 mutation - implications for the p62/NF-κB/Nrf2/autophagy pathways in the selection of individualised therapeutic strategies: a preliminary report [0.03%]
SQSTM1基因突变的ALS病例及p62/NF-κB/Nrf2/自噬途径在个体化治疗策略选择中的意义:初步报告
Kamila Żur-Wyrozumska
Kamila Żur-Wyrozumska
Introduction: Amyotrophic lateral sclerosis (ALS) represents a heterogeneous group of neurodegenerative disorders sharing a common ALS phenotype but arising from diverse genetic and molecular mechanisms. Among the genes i...
Single versus double chest tube after anatomical pulmonary resections - randomized trial [0.03%]
单个胸管与双胸管在解剖型肺切除术中疗效的随机试验研究
Tomasz Gil,Jarosław Kużdżał,Jakub Szadurski et al.
Tomasz Gil et al.
Background: Pleural drainage is the standard procedure after different thoracic procedures. The drainage rules used in various centers vary considerably. Although many centers use now single chest tube instead of the clas...
Randomized Controlled Trial
Folia medica Cracoviensia. 2025 Sep 30;65(3):161-171. DOI:10.24425/fmc.2025.156691 2025
Selected factors burdening the caregiver of a chronically ill person on the example of multiple sclerosis [0.03%]
以多发性硬化症为例影响慢性病患者照顾者的若干因素分析
Ewa Szydło,Katarzyna Wojtas,Anna Szczypta et al.
Ewa Szydło et al.
Introduction: The burden on caregivers of chronically ill patients is a subject of concern for many specialists. The course of multiple sclerosis and the associated change in the patient's functional ability, as well as t...
Can xenobiotics contribute to the increase in the incidence of endocrine diseases by inducing autoimmune processes? [0.03%]
外来物质通过诱导自身免疫过程能否增加内分泌疾病发病率?
Bogusława Budziszewska,Beata Starek-Świechowicz,Stanisław Zieliński et al.
Bogusława Budziszewska et al.
In recent decades, there has been an increase in the incidence of both autoimmune and endocrine diseases, mainly in industrialized countries and may be partly due to human exposure to increasing levels of environmental pollutants. Research ...