Comparison of Bioavailability of Nitrates and Nitrites in 3 Species of Amaranthus: A Randomized, Double-Blind, Placebo-Controlled, 4-Way Crossover Study in Healthy Subjects Under Fasting Conditions [0.03%]
三种苋属植物中硝酸盐和亚硝酸盐生物利用度的比较:健康受试者空腹状态下随机、双盲、安慰剂对照、4周期交叉研究
Deepa Suhag,Aparna Nilesh Kodre
Deepa Suhag
Background: Amaranthus is a significant source of dietary nitrates, which have been known to improve aerobic capacity and exercise performance in physically active individuals. There is a significant data gap on nonpartit...
Safety and Efficacy of a Mesenchymal Stem Cell Secretome Therapy (KPI-012) for Persistent Corneal Epithelial Defects: A Phase 1b Trial [0.03%]
人胎盘间充质干细胞分泌组治疗顽固性角膜上皮缺损的Ib期临床试验:安全性和有效性
Valeria Sánchez Huerta,Hugo Quiroz-Mercado,Enrique O Graue-Hernández et al.
Valeria Sánchez Huerta et al.
Background: Persistent corneal epithelial defect (PCED) is a condition often refractory to conventional treatments. KPI-012 is a topical mesenchymal stem cell secretome therapy under investigation for PCED management. ...
Pumpkin Seeds as a Natural Remedy for Anemia: Nutritional Insights and Therapeutic Potential [0.03%]
南瓜籽作为治疗贫血的天然疗法:营养洞察与治疗潜力
Andugula Swapna Kumari,Gowrishankar Arumugam,Shyamaladevi Babu et al.
Andugula Swapna Kumari et al.
Anemia is a widespread global health concern characterized by reduced hemoglobin levels and diminished oxygen-carrying capacity of the blood. According to the World Health Organization, anemia affects 40% of children aged 6 to 59 months, 37...
Efficacy and Side Effect of Different Doses of Glucocorticoids on Sudden Deafness [0.03%]
不同剂量糖皮质激素治疗突发性聋的疗效及副作用分析
Ya He,Liange Zhi,Yajin Feng et al.
Ya He et al.
Background: Sudden deafness (SD) presents as rapid-onset sensorineural hearing loss within 72 hours, with unknown etiology. Current guidelines recommend systemic corticosteroids as first-line therapy, though high-dose reg...
The Effect of Berberis (Vulgaris and Integerrima) on Cardiovascular Risk Factors in Patients With Type 2 Diabetes Mellitus: A Systematic Review, Meta-Analysis, and GRADE Assessment [0.03%]
药用刺柏对2型糖尿病患者心血管风险因素的影响:系统评价、meta分析和GRADE评估
Vali Musazadeh,Niloofar Hamidi,Morvarid Noormohammadi et al.
Vali Musazadeh et al.
Introduction and aim: Type 2 diabetes mellitus (T2DM) raises cardiovascular disease risk, but evidence on Berberis's impact is limited and inconsistent. This systematic review and meta-analysis aimed to assess effect of B...
Inhibition of Contractility of Isolated Caprine Detrusor by the Rho Kinase Inhibitor Fasudil and Reversal by the Guanylyl Cyclase Inhibitor ODQ [0.03%]
fasudil对去甲肾上腺素诱发的山羊逼尿肌收缩的抑制作用及其对鸟苷酸环化酶抑制剂1H-[1,2]苯并噻唑-7-磺酰胺-1,1-二氧化物(1,1-dioxide 1h-[1,2] Benzothiazine-7-sulfonamide) (ODQ)的作用反应
Niranjana Jeba Jeeviha,Aniket Kumar,Rohini Ann Mathew et al.
Niranjana Jeba Jeeviha et al.
Background: Rho kinase (also called rho-associated protein kinase or ROCK), a serine/threonine kinase, is involved in muscle contractility since it phosphorylates myosin light chain phosphatase, hence inhibiting it. This ...
Real-World Utilization Patterns, Safety, and Efficacy of Tafamidis in Patients With Hereditary Transthyretin Amyloidosis in Japan [0.03%]
日本遗传性转甲状腺素蛋白淀粉样变患者中tafamidis的使用模式、安全性及疗效:真实世界研究
Hiroaki Konishi,Hajime Abe,Noriko Matsumoto et al.
Hiroaki Konishi et al.
Purpose: Patients with hereditary transthyretin (ATTRv) amyloidosis experience progressive degeneration of the somatic and peripheral nervous system that can impair ambulation, autonomy, and quality of life (QOL). Tafamid...
A Randomized, Prospective and Crossover Study, Comparing the Eradication Rate After 10 Days of Concomitant Therapy to Bismuth Quadruple Therapy Among a Sample of the Lebanese Population [0.03%]
利比里亚人群中序贯疗法与铋剂四联疗法根除率的随机、前瞻性交叉研究
Jad Chidiac,Reine-Marie Kahwaji,Souheil Hallit et al.
Jad Chidiac et al.
Background: Concomitant therapy and bismuth quadruple therapy are both recommended as first-line treatment regimens for the empiric treatment of Helicobacter pylori infection, especially after the increased resistance to ...
Assessing the Impact of Frailty Interventions on Older Patients With Frailty [0.03%]
评估针对脆弱老年人的干预措施的影响
Miaoyu Zhang,Lingling Zhong
Miaoyu Zhang
Background: As the global population ages, frailty-marked by diminished physiological reserves and increased vulnerability, poses significant health risks such as falls, hospitalization, and mortality. Exercise therapy, e...
Evaluation of Adverse Effects and Tolerability of Dietary Ginger Supplementation in Patients With Functional Dyspepsia [0.03%]
功能性消化不良患者膳食 ginger 补充的不良反应和耐受性评价
Lemlem Gebremariam Aregawi,Csiki Zoltan
Lemlem Gebremariam Aregawi
Background: Functional dyspepsia (FD) is a prevalent upper gastrointestinal disorder characterized by chronic or recurrent symptoms, including epigastric pain, bloating, and nausea. Ginger (Zingiber officinale), a natural...