Alejandro Martínez Lledín,Marta Mora Massó,Ana Oliva Sánchez et al.
Alejandro Martínez Lledín et al.
Purpose: Insomnia is a common sleep disorder that affects students' academic performance and quality of life. This study aims to assess the prevalence of insomnia among students from various degrees enrolled at several un...
Pharmacodynamics, Safety, and Tolerability of Pyridostigmine Bromide in Heart Failure [0.03%]
溴吡斯的明在心力衰竭中的药理动力学、安全性及耐受性
Randal Goldberg,Lucy Norcliffe-Kaufmann,Horacio Kaufmann et al.
Randal Goldberg et al.
Background: Pyridostigmine bromide is a short-acting carbamate acetylcholinesterase inhibitor that has been shown to acutely augment parasympathetic signaling in cardiovascular disease populations. ...
The Effects of Fasinumab on Peripheral Nerve Function and Ganglion Anatomy: Results From a Randomized, Double-Blind, Placebo-Controlled Study in Patients With Pain Due to Osteoarthritis of the Knee or Hip, and a Series of Nonclinical Studies [0.03%]
关于膝关节或髋关节骨关节炎引起的疼痛患者使用Fasinumab对周围神经功能和节段解剖结构的影响：随机、双盲、安慰剂对照研究及一系列非临床研究结果
Simon Eng,Michael Fetell,Haitao Gao et al.
Simon Eng et al.
Purpose: Osteoarthritis (OA) is a chronic disease where breakdown and loss of cartilage leads to pain, primarily in the joints. Nerve growth factor inhibitors (eg, fasinumab) can reduce pain, but have been associated with...
Francis Dodeller,Peter Alliger,Jens Heyn et al.
Francis Dodeller et al.
Purpose: Aflibercept is a recombinant fusion protein that binds with high affinity to vascular endothelial growth factor A (VEGF-A), and other growth factors, reducing pathological neovascularization and abnormal vascular...
The Effects of Cocoons of Larinus Hedenborgi (Coleoptera: Curculionidae) Extracts on Inflammation and Clinical Outcomes in Patients With Coronavirus Disease 2019: A Double-Blinded Randomized Controlled Clinical Trial [0.03%]
Larinus hedenborgi（coleoptera：curculionidae）化蛹提取物对新型冠状病毒肺炎患者炎症及临床转归影响的双盲随机对照研究
Mahdi Keshani,Sayid Mahdi Mirghazanfari,Naseh Pahlavani et al.
Mahdi Keshani et al.
Background: Severe acute respiratory syndrome coronavirus 2, the causative agent of coronavirus disease 2019 (COVID-19), is an inflammatory disease that manifests with symptoms including dry cough, fever, myalgia, and eve...
Effect of Intravenous Lidocaine on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Colorectal Surgery: A Two-Center, Randomized, Double-Blind Controlled Trial [0.03%]
静脉注射利多卡因对接受腹腔镜结直肠手术患者术后认知功能障碍影响的两中心随机双盲对照试验
Ke-Peng Liu,Jing Dai,Fu-Rong Huang et al.
Ke-Peng Liu et al.
Background: In patients undergoing gastrointestinal surgery, enhancing perioperative cognitive function and facilitating expedited postoperative recovery are critical components for achieving swift rehabilitation. Intrave...
Initiation of Type 2 Diabetes Mellitus Medications in the NGHA Healthcare System in Saudi Arabia: Contemporary Trends [0.03%]
沙特阿拉伯NGHA卫生系统中2型糖尿病药物的起始治疗：当代趋势
Mesnad S Alyabsi,Lolwah Almousa,Anwar H Alqarni et al.
Mesnad S Alyabsi et al.
Background: Continuous updates in management guidelines for type 2 diabetes mellitus (T2DM) have affected treatment patterns. In this study, we aimed to identify the prevalence of initiating various antidiabetic medicatio...
Compatibility and Stability of Cipepofol (Ciprofol) and Etomidate Mixture for Intravenous Anesthesia [0.03%]
注射麻醉的右旋咪达和依托咪酯混合液的相容性和稳定性研究
Linzhong Zhang,Lingchun Kong,Qi Deng et al.
Linzhong Zhang et al.
Objective: To evaluate the physical and chemical compatibility and stability of a cipepofol (ciprofol) and etomidate (EC) mixture for intravenous anesthesia and assess the physiochemical stability of the drugs during co-a...
Reversing Morphine Induced Tolerance: Insights Into Cetirizine and Green Tea Extract Efficacy [0.03%]
吗啡诱导的耐受性逆转：西替利嗪和绿茶提取物有效性的研究启示
Tahereh Eteraf-Oskouei,Adel Mahmoudi Gharehbaba,Solmaz Asnaashari et al.
Tahereh Eteraf-Oskouei et al.
Background: The treatment of chronic pain presents a considerable difficulty, particularly due to opioid dependence, which is marked by tolerance and withdrawal symptoms. Opioids primarily target mu (μ) opioid receptors,...
Cardiovascular Events and Heart Failure in Patients With Type 2 Diabetes Treated With Dipeptidyl Peptidase-4 Inhibitors: A Meta-Analysis [0.03%]
二肽基肽酶-4抑制剂治疗2型糖尿病患者心血管事件和心力衰竭的 meta 分析
Adili Tuersun,Shufen Cui,Li Han et al.
Adili Tuersun et al.
Background: The global prevalence of type 2 diabetes mellitus (T2DM) continues to rise, with patients facing significantly elevated risks of cardiovascular complications, particularly heart failure (HF). ...