Jeffrey J Warren,Jay R Winkler,Harry B Gray
Jeffrey J Warren
Photosynthetic reaction centers (PRCs) employ multiple-step tunneling (hopping) to separate electrons and holes that ultimately drive the chemistry required for metabolism. We recently developed hopping maps that can be used to interpret th...
Recent advances in phenoxyl radical complexes of salen-type ligands as mixed-valent galactose oxidase models [0.03%]
近年来salen型配体phenox基自由基配合物作为混合价态乳糖氧化酶模型的研究进展
Christopher T Lyons,T Daniel P Stack
Christopher T Lyons
The interplay between redox-active transition metal ions and redox-active ligands in metalloenzyme sites is an area of considerable research interest. Galactose oxidase (GO) is the archetypical example, catalyzing the aerobic oxidation of p...
Iron metabolism in aerobes: managing ferric iron hydrolysis and ferrous iron autoxidation [0.03%]
好氧生物的铁代谢：调控三价铁水解和二价铁自氧化反应
Daniel J Kosman
Daniel J Kosman
Aerobes and anaerobes alike express a plethora of essential iron enzymes; in the resting state, the iron atom(s) in these proteins are in the ferrous state. For aerobes, ferric iron is the predominant environmental valence form which, given...
The Rich Electrochemistry and Redox Reactions of the Copper Sites in the Cellular Prion Protein [0.03%]
细胞朊蛋白中铜位点的丰富电化学和氧化还原反应
Feimeng Zhou,Glenn L Millhauser
Feimeng Zhou
This paper reviews recent electrochemical studies of the copper complexes of prion protein (PrP) and its related peptides, and correlates their redox behavior to chemical and biologically relevant reactions. Particular emphasis is placed on...
Anti-diabetic effects of a series of vanadium dipicolinate complexes in rats with streptozotocin-induced diabetes [0.03%]
钒茋化合物的抗糖尿病作用研究
Gail R Willsky,Lai-Har Chi,Michael Godzala rd et al.
Gail R Willsky et al.
The effects of oral treatment of rats with streptozotocin-induced diabetes with a range of vanadium dipicolinate complexes (Vdipic) and derivatives are reviewed. Structure-reactivity relationships are explored aiming to correlate properties...
Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions [0.03%]
一氧化氮合酶调节机制：电子传递与结构域相互作用
Changjian Feng
Changjian Feng
Nitric oxide synthase (NOS), a flavo-hemoprotein, tightly regulates nitric oxide (NO) synthesis and thereby its dual biological activities as a key signaling molecule for vasodilatation and neurotransmission at low concentrations, and also ...
Yan Zhang,Steffen Rump,Vadim N Gladyshev
Yan Zhang
The trace element molybdenum (Mo) is the catalytic component of important enzymes involved in global nitrogen, sulfur, and carbon metabolism in both prokaryotes and eukaryotes. With the exception of nitrogenase, Mo is complexed by a pterin ...
Jacqueline K Barton,Eric D Olmon,Pamela A Sontz
Jacqueline K Barton
In all organisms, oxidation threatens the integrity of the genome. DNA-mediated charge transport (CT) may play an important role in the generation and repair of this oxidative damage. In studies involving long-range CT from intercalating Ru...
M≡E and M=E Complexes of Iron and Cobalt that Emphasize Three-fold Symmetry (E = O, N, NR) [0.03%]
突出三重对称性的铁和钴的M≡E和M=E配合物（E = O，N，NR）
Caroline T Saouma,Jonas C Peters
Caroline T Saouma
Mid-to-late transition metal complexes that feature terminal, multiply bonded ligands such as oxos, imides, and nitrides have been invoked as intermediates in several catalytic transformations of synthetic and biological significance. Until...
Partha Basu,Sharon J N Burgmayer
Partha Basu
The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molec...