Control and utilization of ruthenium and rhodium metal complex excited states for photoactivated cancer therapy [0.03%]
基于金属钌和铑配合物的激发态调控及其光活化抗肿瘤研究
Jessica D Knoll,Claudia Turro
Jessica D Knoll
The use of visible light to produce highly selective and potent drugs through photodynamic therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed to follow an O2-dependent mechanism by producing highly rea...
Karin J Young,Lauren A Martini,Rebecca L Milot et al.
Karin J Young et al.
Light-driven water oxidation is an essential step for conversion of sunlight into storable chemical fuels. Fujishima and Honda reported the first example of photoelectrochemical water oxidation in 1972. In their system, TiO2 was irradiated ...
Marvin W Makinen,Marzieh Salehitazangi
Marvin W Makinen
Much emphasis has been given to vanadium compounds as potential therapeutic reagents for the treatment of diabetes mellitus. Thus far, no vanadium compound has proven efficacious for long-term treatment of this disease in humans. Therefore,...
The coordination chemistry and magnetism of some 3d-4f and 4f amino-polyalcohol compounds [0.03%]
一些3d-4f和4f氨基多元醇化合物的配位化学与磁性研究
Joseph W Sharples,David Collison
Joseph W Sharples
Triethanolamine, teaH3, and diethanolamine, RdeaH2, 3d-4f and 4f compounds demonstrate an enormous variety in their structure and bonding. This review examines the synthetic strategies to these molecules and their magnetic properties, whils...
Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers [0.03%]
非典型配位单核非血红素铁(II)中心的结构与功能
Daniela Buongiorno,Grit D Straganz
Daniela Buongiorno
Mononuclear, non-heme-Fe(II) centers are key structures in O2 metabolism and catalyze an impressive variety of enzymatic reactions. While most are bound via two histidines and a carboxylate, some show a different organization. A short overv...
Novel Approaches for the Accumulation of Oxygenated Intermediates to Multi-Millimolar Concentrations [0.03%]
积累氧中间体的新方法达到毫摩尔浓度
Carsten Krebs,Laura M K Dassama,Megan L Matthews et al.
Carsten Krebs et al.
Metalloenzymes that utilize molecular oxygen as a co-substrate catalyze a wide variety of chemically difficult oxidation reactions. Significant insight into the reaction mechanisms of these enzymes can be obtained by the application of a co...
Designing functional metalloproteins: from structural to catalytic metal sites [0.03%]
从结构金属位点到催化金属位点——设计功能金属蛋白
Melissa L Zastrow,Vincent L Pecoraro
Melissa L Zastrow
Metalloenzymes efficiently catalyze some of the most important and difficult reactions in nature. For many years, coordination chemists have effectively used small molecule models to understand these systems. More recently, protein design h...
X-ray absorption near-edge spectroscopy in bioinorganic chemistry: Application to M-O2 systems [0.03%]
基于X射线吸收精细结构的生物无机化学研究及其在M-O_2体系中的应用
Ritimukta Sarangi
Ritimukta Sarangi
Metal K-edge X-ray absorption spectroscopy (XAS) has been extensively applied to bioinorganic chemistry to obtain geometric structure information on metalloprotein and biomimetic model complex active sites by analyzing the higher energy ext...
CO, NO and O2 as Vibrational Probes of Heme Protein Interactions [0.03%]
一氧化碳、一氧化氮和氧气作为血红蛋白相互作用的振动探针
Thomas G Spiro,Alexandra V Soldatova,Gurusamy Balakrishnan
Thomas G Spiro
The gaseous XO molecules (X = C, N or O) bind to the heme prosthetic group of heme proteins, and thereby activate or inhibit key biological processes. These events depend on interactions of the surrounding protein with the FeXO adduct, inte...
Kinetics and thermodynamics of formation and electron-transfer reactions of Cu-O2 and Cu2-O2 complexes [0.03%]
关于Cu-O2和Cu2-O2复合物的形成及电子转移反应的动力学与热力学研究
Shunichi Fukuzumi,Kenneth D Karlin
Shunichi Fukuzumi
The kinetics and thermodynamics of formation of Cu(II)-superoxo (Cu-O2) complexes by the reaction of Cu(I) complexes with dioxygen (O2) and the reduction of Cu(II)-superoxo complexes to dinuclear Cu-peroxo complexes are discussed. In the fo...