Sesquiterpenes from Ainsliaea fragrans and their inhibitory activities against cyclooxygenases-1 and 2 [0.03%]
香气母挥发油中抗环氧合酶活性成分的研究
Hao Wang,Ting Wu,Ming Yan et al.
Hao Wang et al.
One new guaiane-type sesquiterpene glycoside, 2'-O-E-caffeoyl-8alpha-hydroxy-11alpha,13-dihydro-3beta-O-beta-D-glucozaluzanin C (1), was isolated from the whole herb of Ainsliaea fragrans (Compositae), together with five known sesquiterpene...
Novel furanylarylene arylsulfonylindolesulfonamides: synthesis and their antibacterial evaluation [0.03%]
新型呋喃茋芳基磺酰胺衍生物的合成及抗菌活性评价
Chennan Ramalingan,In-Sook Lee,Young-Woo Kwak
Chennan Ramalingan
An array of furanylarylene arylsulfonylindolesulfonamides was synthesized through multi-step synthetic protocols involving bromination, stannylation, Stille cross coupling, reduction, arylsulfonylation, chlorosulfonylation, and condensation...
Potency fingerprint of herbal products Danshen injection for their quality evaluation [0.03%]
丹参注射液的质量标志物及其指纹图谱研究
Yan-Xu Chang,Dong-Mei Yan,Lin-Lin Chen et al.
Yan-Xu Chang et al.
The fingerprint technique has been studied frequently as a useful strategy for quality of traditional Chinese medicine. A novel potency fingerprint that can quantitatively analyze the antioxidant activity of individual constituent and provi...
Synthesis of new 2-thio-[1,2,4]triazolo[1,5-c]quinazoline derivatives and its antimicrobial activity [0.03%]
新型2-硫代-[1,2,4]三唑并[1,5-c]喹唑啉衍生物的合成及其抗菌活性研究
Lyudmila Antipenko,Alexander Karpenko,Sergey Kovalenko et al.
Lyudmila Antipenko et al.
A series of novel ([1,2,4]triazolo[1,5-c]quinazolin-2-ylthio)carboxylic acids 2a-d and esters 3a-l were synthesized and evaluated for antimicrobial activity. Alkylation of potassium 2-thio-[1,2,4]triazolo[1,5-c]quinazoline 1 with halogenoca...
Effect of an experimental design for evaluating the nonlinear optimal formulation of theophylline tablets using a bootstrap resampling technique [0.03%]
Bootstrap重采样技术在评价茶碱 Tablets非线性最优处方中的效应研究
Hiroaki Arai,Tatsuya Suzuki,Chosei Kaseda et al.
Hiroaki Arai et al.
The optimal solutions of theophylline tablet formulations based on datasets from 4 experimental designs (Box and Behnken design, central composite design, D-optimal design, and full factorial design) were calculated by the response surface ...
Design, synthesis and evaluation of tetrahydroisoquinolines as new kinesin spindle protein inhibitors [0.03%]
新型马达蛋白紫杉烷类似物抗肿瘤活性研究进展
Cheng Jiang,Qidong You,Fei Liu et al.
Cheng Jiang et al.
In this study, a series of tetrahydroisoquinolines have been synthesized and identified as novel kinesine spindle protein (KSP) inhibitors based on the pharmacophore we have mapped and the crystal structure of monastrol bound to the target ...
Synthesis and bioassay of oxazolyl/thiazolyl selenadiazoles, thiadiazoles and diazaphospholes [0.03%]
含硒、硫化合物及磷杂环的合成与生物测定研究
Venkatapuram Padmavathi,Konda Mahesh,Annaji Venkata Nagendra Mohan et al.
Venkatapuram Padmavathi et al.
A new class of bis heterocycles, oxazolyl/thiazolyl selenadiazoles, thiadiazoles and diazaphospholes were prepared from phenacylsulfonylacetic acid methyl ester and tested for their antimicrobial and antioxidant properties.
Synthesis and antimicrobial activity of some 5-substituted-3-phenyl-Nbeta-(substituted-2-oxo-2H-pyrano[2,3-b]quinoline-3-carbonyl)-1H-indole-2-carboxyhydrazide [0.03%]
一些5位取代的-3-苯基-Nβ-(取代-2-氧代-2H-吡喃并[2,3-b]喹啉-3-甲酰基)-1H-吲哚-2-甲酰胺腙化合物的合成及其抗菌活性研究
Basavarajaiah Suliphal Devara Mathada,Mruthyunjayaswamy Bennikallu Hire Mathada
Basavarajaiah Suliphal Devara Mathada
Ethyl 3-oxo-3-{2-[(5-substituted-3-phenyl-1H-indol-2-yl)carbonyl]hydrazinyl}propanoates 5a-b were synthesized according to the literature method. These on further reaction with substituted-2-hydroxy-3-formylquinolines 3a-e yielded 5-substit...
Synthesis and structural pattern recognition of 5-(2'-alkoxycarbonyl-substituted phenoxy)furfural derivatives [0.03%]
5-（2'-代羧基取代苯氧基）糠醛衍生物的合成与结构模式识别
Chia-Lin Chang
Chia-Lin Chang
The ethyl 5-(2'-alkoxycarbonyl-substituted phenoxy)furan-2-carboxylates (1C-13C) showed good anti-platelet aggregation,(1)) anti-allergic(2)) and anti-inflammatory activities.(2)) A series of 5-(2'-alkoxycarbonyl-substituted phenoxy)furfura...
Preparation and evaluation of gastroretentive floating tablets of Silymarin [0.03%]
夹竹桃麻素胃滞留漂浮片的制备及评价研究
Rajeev Garg,Ghanshyam Das Gupta
Rajeev Garg
The present study performed by preparation and evaluation of floating tablets of Silymarin as model drug for prolongation of gastric residence time. Floating effervescent tablets were formulated by various materials like hydroxypropyl methy...