Effects of uric acid on nitrosation of N-acetylcysteine by diethylamine NONOate and N-acetyl-N-nitrosotryptophan [0.03%]
尿酸对N-乙酰半胱氨酸的亚硝基化作用的影响：二乙胺NONOate和N-乙酰-N-硝基色氨酸的作用
Toshinori Suzuki,Atsushi Naka,Haruka Kimura
Toshinori Suzuki
Uric acid of human plasma concentration accelerated nitrosation of N-acetylcysteine by diethylamine NONOate at neutral pH, but diminished that of N-acetyltryptophan. Uric acid also accelerated nitrosation of N-acetylcysteine by N-acetyl-N-n...
Xiao-Long Yang,Zheng-Hong Xie,Xian-Jun Jiang et al.
Xiao-Long Yang et al.
A new acridone alkaloid, 1,3-dihydroxy-4-methoxy-10-methylacridone (1), was isolated from leaves of the plant Micromelum integerrimum, together with two known carbazole alkaloids, glycozolinol (2) and methyl carbazole-3-carboxylate (3). The...
Two new acyclic diterpene glycosides from fruits of Habanero, Capsicum chinense [0.03%]
habanero辣椒果实中的两种新的非环状二萜糖苷
Jong-Hyun Lee,Mona El-Aasr,Tsuyoshi Ikeda et al.
Jong-Hyun Lee et al.
Four acyclic diterpene glycosides were extracted from Habanero, the fruits of Capsicum chinense JACQ., which is known as one of the hottest peppers in existence. Two of these glycosides were identified as capsianoside XIII and capsianoside ...
Yoshihiro Mimaki,Kazuki Watanabe,Yukiko Matsuo et al.
Yoshihiro Mimaki et al.
Six new triterpene glycosides (1-6), together with 11 known ones (7-17), have been isolated from a glycoside-enriched fraction prepared from the tubers of Anemone coronaria L. (Ranunculaceae). On the basis of extensive spectroscopic analysi...
Emiko Yae,Shoji Yahara,Mona El-Aasr et al.
Emiko Yae et al.
Two new guaiane-type sesquiterpene (1, 2), 2 new phenylpropanoid derivatives (3, 4), and 5-oxo-11-hydroxy-8(Z)-undecenoic acid 11-O-glucoside (5), together with 17 known compounds have been isolated from the whole plants of Youngia japonica...
Combining a solution-phase derived library with in-situ cellular bioassay: prompt screening of amide-forming minilibraries using MTT assay [0.03%]
溶液相合成的化合物库与细胞内活性筛选结合用于快速筛选形成酰胺类小分子化合物库的MTT实验方法学研究
Li-Wu Chiang,Kai Pei,Shao-Wei Chen et al.
Li-Wu Chiang et al.
We constructed a minilibrary using a solution-phase synthesis through coupling of three core amino compounds (5'-amino-5'-deoxy uridine, 5'-amino-2',5'-di-deoxy arabinosyl uridine, and butan-1-amine) with 30 carboxylic acids via amide bond ...
Clean and direct synthesis of alpha,alpha'-bithiophenes and bipyrroles by metal-free oxidative coupling using recyclable hypervalent iodine(III) reagents [0.03%]
一种可回收的三价碘试剂在无金属氧化偶联合成α,α'-联噻吩和二吡咯中的应用
Toshifumi Dohi,Koji Morimoto,Chieko Ogawa et al.
Toshifumi Dohi et al.
The facile and clean oxidative biaryl coupling reaction of thiophenes and pyrroles has been achieved using the recyclable hypervalent iodine(III) reagents having adamantane or methane structures. These iodine(III) reagents could be recovere...
Pharmacophore modeling and virtual screening studies of checkpoint kinase 1 inhibitors [0.03%]
检控激酶1抑制剂的药效团建模和计算机虚拟筛选研究
Jin-Juan Chen,Ting-Lin Liu,Li-Jun Yang et al.
Jin-Juan Chen et al.
In this study, chemical feature-based 3-dimensional (3D) pharmacophore models of Checkpoint kinase 1 (Chk1) inhibitors were developed based on the known inhibitors of Chk1. The best pharmacophore model Hypo1 was characterized by the best co...
The generation of lucigenin chemiluminescence from the reaction of guanidino compounds with phenylglyoxal under alkaline conditions and its application [0.03%]
碱性条件下亚焦儿康酸与胍类化合物反应生成鲁米诺化学发光及其应用研究
Yukio Nohara,Tomomi Usui,Junko Suzuki et al.
Yukio Nohara et al.
It is shown that o-carboxyphenylglyoxal, which is converted from ninhydrin by alkali, produces a chemiluminescent lucigenin reaction under alkaline conditions when with reacted with guanidino compounds. It is also demonstrated that phenylgl...
Stability of binary and ternary copper(II) complexes with 1,10-phenanthroline, 2,2'-bipyridyl and some alpha-amino acids in aqueous medium [0.03%]
含苯并咪唑、联吡啶和一些α-氨基酸的铜（Ⅱ）二元及三元配合物在水介质中的稳定性研究
Naciye Türkel,Ciğdem Sahin
Naciye Türkel
Interactions of certain amino acids with some metal ions have significant consequences in biological systems. Metal ions can act as co-factors in the regulation of enzymatic reactions. Interactions of metal ions with amino acid side chains ...