Massimo Terzolo,Silvia Bovio,Anna Pia et al.
Massimo Terzolo et al.
Subclinical Cushing's syndrome (CS) is attracting increasing interest since the serendipitous discovery of an adrenal mass has become a rather frequent event owing to the routine use of sophisticated radiologic techniques. Cortical adenoma ...
Pediatric Cushing's syndrome: clinical features, diagnosis, and treatment [0.03%]
儿科库欣综合征：临床特点、诊断和治疗
Li F Chan,Helen L Storr,Ashley B Grossman et al.
Li F Chan et al.
Cushing's syndrome (CS) results from prolonged exposure to supraphysiological levels of circulating glucocorticoids, endogenously or exogenously derived. Although rare in childhood, CS remains a difficult condition to diagnose and treat. A ...
Nora Maria Elvira Albiger,Carla M Scaroni,Franco Mantero
Nora Maria Elvira Albiger
Cyclic Cushing's syndrome (CS) is a disorder in which glucocorticoid levels are alternately normal and high, the latter occurring in episodes that can last from a few days to several months. It is more common in children than in adults. Cyc...
Dimitra Vassiliadi,Stylianos Tsagarakis
Dimitra Vassiliadi
Although in the majority of the patients with Cushing's syndrome (CS), hypercortisolism is due to ACTH hypersecretion by a pituitary tumour or to ectopic ACTH secretion from an extrapituitary neoplastic lesion or to autonomous cortisol secr...
Primary pigmented nodular adrenocortical disease and Cushing's syndrome [0.03%]
原发性色素结节性肾上腺皮质疾病及其所致库欣综合征
Anelia Horvath,Constantine Stratakis
Anelia Horvath
Primary pigmented nodular adrenocortical disease (PPNAD) is a form of bilateral adrenocortical hyperplasia that is often associated with corticotrophin (ACTH)-independent Cushing's syndrome (CS) and is characterized by small to normal-sized...
Cushing's syndrome secondary to ACTH-independent macronodular adrenal hyperplasia [0.03%]
异位ACTH综合征继发的原发性色素结节性肾上腺皮质增生
Marcia Helena Soares Costa,André Lacroix
Marcia Helena Soares Costa
ACTH-Independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of endogenous Cushing's syndrome (CS), in which clinical features usually become apparent only after several decades of life. This form of adrenal hyperplasia typical...
Ectopic ACTH syndrome [0.03%]
异位ACTH综合征
Andrea M Isidori,Andrea Lenzi
Andrea M Isidori
Ectopic adrenocorticotropic secretion (EAS) is responsible for 12-17% of cases of Cushing's syndrome (CS) and covers a range of tumours, from undetectable benign lesions to widespread metastases. The syndrome is often associated with severe...
Lucio Vilar,Maria da Conceição Freitas,Manuel Faria et al.
Lucio Vilar et al.
Among endocrine disorders, Cushing's syndrome (CS) is certainly one of the most challenging to endocrinologists due to the difficulties that often appear during investigation. The diagnosis of CS involves two steps: confirmation of hypercor...
John Newell-Price,Ashley B Grossman
John Newell-Price
The differential diagnosis of Cushing's syndrome requires careful multidisciplinary interaction with a number of specialities, co-ordinated through endocrine centres with good experience of this condition. It is essential that the diagnosis...
Margaret de Castro,Ayrton C Moreira
Margaret de Castro
Cushing's syndrome (CS) results from sustained pathologic hypercortisolism. The clinical features are variable and the most specific features for CS include abnormal fat distribution, particularly in the supraclavicular and temporal fossae,...