Mauro A Czepielewski,Guilherme A F S Rollin,Alessandra Casagrande et al.
Mauro A Czepielewski et al.
We review the clinical and biochemical criteria used for evaluation of the transsphenoidal pituitary surgery results in the treatment of Cushing's disease (CD). Firstly, we discuss the pathophysiology of the hypothalamic-pituitary-adrenal a...
Prospective evaluation of transsphenoidal pituitary surgery in 108 patients with Cushing's disease [0.03%]
经蝶窦垂体手术治疗库欣病108例的前瞻性研究
Guilherme Rollin,Nelson Pires Ferreira,Mauro A Czepielewski
Guilherme Rollin
Transsphenoidal pituitary surgery (TSS) remains the treatment of choice for Cushing's disease (CD). Despite the widespread acceptance of this procedure as the first line treatment in CD, the indication of a second TSS in not cured or relaps...
Role for laparoscopic adrenalectomy in patients with Cushing's syndrome [0.03%]
库欣综合征患者的腹腔镜肾上腺切除术的作用
William F Young Jr,Geoffrey B Thompson
William F Young Jr
Laparoscopic adrenalectomy is one of the most clinically important advances in the past 2 decades for the treatment of adrenal disorders. When compared to open adrenalectomy, laparoscopic adrenalectomy is equally safe, effective, and curati...
Cuong Nguyen Dang,Peter Trainer
Cuong Nguyen Dang
The treatment of choice for Cushing's syndrome remains surgical. The role for medical therapy is twofold. Firstly it is used to control hypercortisolaemia prior to surgery to optimize patient's preoperative state and secondly, it is used wh...
The role of bilateral inferior petrosal sinus sampling in the diagnosis of Cushing's syndrome [0.03%]
双侧下副蝶窦采样在库欣综合征诊断中的作用
Andrea Utz,Beverly M K Biller
Andrea Utz
Adrenocorticotropin hormone (ACTH)-dependent Cushing's syndrome is most often due to a pituitary corticotroph adenoma, with ectopic ACTH-secreting tumors representing approximately 15% of cases. Biochemical and radiological techniques have ...
Anju Sahdev,Rodney H Reznek,Jane Evanson et al.
Anju Sahdev et al.
Once the diagnosis of Cushing's syndrome (CS) has been established, the main step is to differentiate between ACTH dependent and independent disease. In adults, 80% of CS is due to ACTH-dependent causes and 20% due to adrenal causes. ACTH-s...
Niki Karavitaki,Olaf Ansorge,John A H Wass
Niki Karavitaki
Silent corticotroph pituitary adenomas (SCA) are defined as pituitary adenomas showing positive staining for adrenocorticotrophic hormone in immunohistochemical studies, but not associated with perioperative clinical or laboratory features ...
[Pseudo-Cushing states] [0.03%]
[Cushings病态]
Daniella J P C Romanholi,Luiz Roberto Salgado
Daniella J P C Romanholi
Pseudo-Cushing syndromes are a heterogeneous group of disorders, including alcoholism, anorexia nervosa, visceral obesity, and depression, which share many of the clinical and biochemical features of Cushing's syndrome. The mechanisms respo...
Lucio Vilar,Maria da Conceição Freitas,Lúcia Helena C Lima et al.
Lucio Vilar et al.
Cushing's syndrome (CS) during pregnancy is a rare condition with fewer than 150 cases reported in the literature. Adrenal adenomas were found to be the commonest cause, followed by Cushing's disease. The gestation dramatically affects the ...
Daniella J P C Romanholi,Luiz Roberto Salgado
Daniella J P C Romanholi
Glucocorticoids are widely used in clinical practice to control the activity of autoimmune, inflammatory, allergic diseases and other nosological entities. Therapeutic doses of glucocorticoids are often administered inappropriately and it i...