Brain-Derived Neurotrophic Factor (BDNF) and Serotonin Transporter (SERT) in Platelets of Patients with Mild Huntington's Disease: Relationships with Social Cognition Symptoms [0.03%]
轻度亨廷顿舞蹈病患者血小板中脑源性神经营养因子(BDNF)和五羟色胺转运蛋白(SERT)的相关性与社会认知症状的关系
L Betti,L Palego,E Unti et al.
L Betti et al.
Deficits in social-cognition processing have been identified during early stages of Huntington Disease (HD), attracting interest on their relevance as possible predictors of neurodegenerative progression. Since the neurotrophin Brain-Derive...
C Pierpaoli,N Foschi,C Cagnetti et al.
C Pierpaoli et al.
Imitation is a human ability rooted in early life. It allows people to interact with each other by observing and reproducing simple and complex movements alike. Imitation can occur in at least two forms: the rst, de ned as anatomical, seems...
Neural functional correlates of emotional processing in patients with first-episode psychoses: an activation likelihood estimation (ALE) meta-analysis [0.03%]
首次精神病发作患者的神经功能相关情感处理元分析激活似然估计(ALE))
A Del Casale,C Rapinesi,G D Kotzalidis et al.
A Del Casale et al.
Background: Early emotional recognition impairment characterises rst-episode psychoses (FEP) and remains stable thereafter. Patients with FEP consistently show brain activation changes during emotional processing in funct...
Structural modeling of altered CLCN1 conformation following a novel mutation in a patient affected by autosomal dominant myotonia congenita (Thomsen disease) [0.03%]
CLCN1新型突变患者骨骼肌中的离子通道构象变化及结构模型构建研究
Rosangela Ferese,Veronica Albano,Mattia Falconi et al.
Rosangela Ferese et al.
Protective effects of long-term lithium administration in a slowly progressive SMA mouse model [0.03%]
锂长期给药对渐进式脊髓性肌萎缩症小鼠模型的保护作用
Francesca Biagioni,Michela Ferrucci,Larisa Ryskalin et al.
Francesca Biagioni et al.
In the present study we evaluated the long-term effects of lithium administration to a knock-out double transgenic mouse model (Smn-/-; SMN1A2G+/-; SMN2+/+) of Spinal Muscle Atrophy type III (SMA-III). This model is characterized by very lo...
Fiona Limanaqi,Stefano Gambardella,Gloria Lazzeri et al.
Fiona Limanaqi et al.
Amyotrophic Lateral Sclerosis (ALS) is a fast progressive neurodegenerative disease characterized by muscle denervation, weakening and atrophy, which eventually culminates into death, mainly due to respiratory failure. The traditional view ...
Therapy in Amyotrophic Lateral Sclerosis (ALS): an unexpected evolving scenario [0.03%]
渐冻症(肌萎缩侧索硬化)的治疗：意想不到的发展局面
Vincenzo Silani
Vincenzo Silani
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease resulting in increasing disability, being uniformly fatal. Since its approval in the 1990s, riluzole remained for long time the unique treatment, offering modest...
The multisystem degeneration amyotrophic lateral sclerosis - neuropathological staging and clinical translation [0.03%]
多系统变性运动神经元病-神经病理分期与临床转化
Federico Verde,Kelly Del Tredici,Heiko Braak et al.
Federico Verde et al.
Amyotrophic lateral sclerosis (ALS) is traditionally considered a disease affecting exclusively motor neurons. However, much evidence points towards additional involvement of brain systems other than the motor. As much as half of ALS patien...
Imaging techniques in ALS [0.03%]
ALS中的影像学技术
Fulvio Zaccagna,Giulia Lucignani,Eytan Raz et al.
Fulvio Zaccagna et al.
Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease characterized by degeneration of both upper and lower motor neuron located in the spinal cord and brainstem. Diagnosis of ALS is predominantly clinical, neverthe...
Cross-talk between pathogenic mechanisms in neurodegeneration: the role of oxidative stress in Amyotrophic Lateral Sclerosis [0.03%]
神经退行性疾病发病机制间的相互作用：氧化应激在肌萎缩侧索硬化症中的作用
Lucia Chico,Martina Modena,Annalisa Lo Gerfo et al.
Lucia Chico et al.
The mechanisms underlying motoneuron degeneration in amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder that affects the motor system with progressive paralysis, are complex and not yet fully understood. It is generally agree...