On-chip microscale isoelectric focusing enhances protein detection limit [0.03%]
芯片级微米等电聚焦技术提高蛋白质检测限
Xiao Fan,Xiaoyu Zhang,Huilu Bao et al.
Xiao Fan et al.
Enhancing the detection limit in protein analysis is essential for a wide range of biomedical applications. In typical fluorescent protein assays, this limit is constrained by the detection capacity of the photon detector. Here, we develop ...
Spectral tweezers: Single sample spectroscopy using optoelectronic tweezers [0.03%]
光谱镊子：使用光电子镊子进行单样本光谱分析
Mohammad Asif Zaman,Mo Wu,Wei Ren et al.
Mohammad Asif Zaman et al.
A scheme that combines optoelectronic tweezers (OET) with spectroscopic analysis is presented. Referred to as spectral tweezers, the approach uses a single focused light beam that acts both as the trapping beam for OET and the probe beam fo...
Prabodh Kumar Pandey,Gilberto Gonzalez,Frederick Cheong et al.
Prabodh Kumar Pandey et al.
Visualizing micro- and nano-scale biological entities requires high-resolution imaging and is conventionally achieved via optical microscopic techniques. Optical diffraction limits their resolution to ∼200 nm. This limit can be overcome by...
An embedded microfluidic valve for dynamic control of cellular communication [0.03%]
一种用于动态控制细胞通讯的嵌入式微流体阀
Mark A DeAngelis,Warren C Ruder,Philip R LeDuc
Mark A DeAngelis
The communication between different cell populations is an important aspect of many natural phenomena that can be studied with microfluidics. Using microfluidic valves, these complex interactions can be studied with a higher level of contro...
Spatially resolved readout of a Fabry-Perot ultrasound sensor interrogated through a multimode optical fiber using wavefront shaping [0.03%]
基于波前整形的多模光纤法布里珀罗超声传感器的空间分辨读出技术研究
Benjamin Keenlyside,Dylan Marques,Nathaniel Redgewell et al.
Benjamin Keenlyside et al.
The spatially resolved interrogation of a Fabry-Perot ultrasound sensor using a laser beam focused through a multimode fiber is demonstrated. To scan the beam across the sensor as required to read it out, optical wavefront shaping was emplo...
Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds [0.03%]
声波响应支架中声滴蒸发的力学和声空化实时时空表征
Mitra Aliabouzar,Bachir A Abeid,Oliver D Kripfgans et al.
Mitra Aliabouzar et al.
Phase-shift droplets provide a flexible and dynamic platform for therapeutic and diagnostic applications of ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound, via the mechanism termed acoustic droplet vap...
Howuk Kim,Bohua Zhang,Huaiyu Wu et al.
Howuk Kim et al.
Endovascular sonothrombolysis has gained significant attention due to its benefits, including direct targeting of the thrombus with sonication and reduced side effects. However, the small aperture of endovascular transducers restricts the i...
Resolution improvement of optoelectronic tweezers using patterned electrodes [0.03%]
基于图案电极的光镊分辨率提升方法研究
Mohammad Asif Zaman,Mo Wu,Wei Ren et al.
Mohammad Asif Zaman et al.
An optoelectronic tweezer (OET) device is presented that exhibits improved trapping resolution for a given optical spot size. The scheme utilizes a pair of patterned physical electrodes to produce an asymmetric electric field gradient. This...
Trap-Integrated Superconducting Nanowire Single-Photon Detectors with Improved RF Tolerance for Trapped-Ion Qubit State Readout [0.03%]
改进射频耐受性的陷俘集成超导纳米线单光子探测器用于离子量子比特读出
Benedikt Hampel,Daniel H Slichter,Dietrich Leibfried et al.
Benedikt Hampel et al.
State readout of trapped-ion qubits with trap-integrated detectors can address important challenges for scalable quantum computing, but the strong rf electric fields used for trapping can impact detector performance. Here, we report on NbTi...
Extreme nonlinear optics in a long pulse regime: High harmonic generation of picosecond mid-IR pulses in polycrystalline zinc selenide [0.03%]
长脉冲下的极端非线性光学现象：几种多晶硒化锌材料中皮秒中红外脉冲的高次谐波生成效应研究
Christopher B Marble,Carl R Sanderson,Charles W Ballmann et al.
Christopher B Marble et al.
High harmonic generation (HHG) in semiconductors has been extensively studied recently in the high-intensity limit using middle infrared (mid-IR) femtosecond laser pulses resulting in emission spectra of self-phase modulated harmonics resti...