ANTI-OXIDATIVE, (α-GLUCOSIDASE AND α-AMYLASE INHIBITORY ACTIVITY OF VITEX DONIANA: POSSIBLE EXPLOITATION IN THE MANAGEMENT OF TYPE 2 DIABETES [0.03%]
维藤豆胶藤抑制氧化、α-葡萄糖苷酶和α-淀粉酶活性：在2型糖尿病管理中的潜在开发与应用研究
Mohammed Auwal Ibrahim,Neil Anthony Koorbanally,Shahidul Islam
Mohammed Auwal Ibrahim
Vitex doniana is an important African medicinal plant traditionally used for the treatment of many diseases including type 2 diabetes (T2D). In this study, ethyl acetate, ethanol and aqueous extracts of the stem bark, root and leaf of V. do...
EFFECT OF JASMONIC ACID ON TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF EXTRACT FROM THE GREEN AND PURPLE LANDRACES OF SWEET BASIL [0.03%]
茉莉酸对紫茎和绿茎泰国甜罗勒提取物总量及抗氧化活性的影响
Fatemeh Malekpoor,Azam Salimi,Abdollah Ghasemi Pirbalouti
Fatemeh Malekpoor
Basil (Ocimum basilicun L.) belongs to the family Lamiaceae and is an important aromatic and medicinal plant, which it widely cultivated in many countries. This plant is a good source of phenolic com- pounds and natural antioxidants. The ma...
ANTIOXIDANT, ANTIBACTERIAL AND GUT MODULATING ACTIVITIES OF KALANCHOE LACINIATA [0.03%]
Kalanchoe laciniata的抗氧化、抗菌及肠道调节作用
Shahid M Iqbal,Qurratulain Jamil,Nauman Jamil et al.
Shahid M Iqbal et al.
Kalanchoe laciniata (L.) DC. (Crassulaceae) is a widely distributed plant in Africa and Asia. Traditionally, various communities use this plant for the treatment of a variety of ailments such as gut prob- lems, allergic conditions and wound...
ASSESSMENT OF SOME BIOLOGICAL ACTIVITIES OF ALYSSUM L. KNOWN AS MADWORT [0.03%]
Alyssum属（牻牛儿苗属）植物的生物活性研究进展及药用价值评估
Cennet Ozay,Ramazan Mammadov
Cennet Ozay
In this research the phenolic composition, and antioxidant, antibacterial and cytotoxic activities of the methanolic extracts obtained from three Alyssum L. taxa (A.foliosum var. megalocaipum, A. simplex and A. stHgosum subsp. stfigosum) we...
SYNTHESIS AND IMMUNOREGULATORY PROPERTIES OF SELECTED 5-AMINO-3-METHYL-4-ISOXAZOLECARBOXYLIC ACID BENZYLAMIDES [0.03%]
5-氨基-3-甲基-4-异噁唑甲酸苄胺的合成及其免疫调节活性研究
Marcin Maczynski,Jolanta Artym,Maja Kocieba et al.
Marcin Maczynski et al.
The aim of the study was to characterize a series of isoxazole derivatives in several immunological tests in vitro and in vivo, in mouse and human models. The human model included measurement of: viability of peripheral blood mononuclear ce...
IN SILICO ADME STUDIES OF POLYAMINE CONJUGATES AS POTENTIAL ANTICANCER DRUGS [0.03%]
聚胺缀合物作为潜在的抗肿瘤药物的计算机辅助ADME研究
Marta Szumilak,Wieslawa Lewgowd,Andrzej Stanczak
Marta Szumilak
The ADME properties and drug-likeness of several polyamine derivatives containing dimeric phthalimide, quinoline, cinnoline and chromone moieties with three different polyamines: 1,4-bis(3-aninopropyl)piperazine, 4,9-dioxa-1,12-dodecanediam...
SYNTHETIC DERIVATIVES OF ISOQUINOLINE, DICARBOXYLIC ACID IMIDES AND THIOIMIDES AS BIOACTIVE COMPOUNDS [0.03%]
异喹啉、二羧酸亚胺和硫代亚胺的衍生物作为生物活性化合物
Jolanta Solecka,Aleksandra Rajnisz,Magdalena Postek et al.
Jolanta Solecka et al.
This study is a continuation of a research program aimed at identifying potent drugs against bacterial infections, in which a series of organic compounds: dicarboxylic acid imides and thioimides, isoquinoline derivatives and open chain comp...
SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING STUDIES OF AROMATIC SULFONAMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS [0.03%]
芳香族磺胺衍生物的合成、生物评价及分子对接研究作为抗炎和止痛剂
Hebat-Allah S Abbas,Somaia S Abdel-Karim,Entesar M Ahmed et al.
Hebat-Allah S Abbas et al.
In this study, [4-(N-substituted sulfamoyl)phenyl]carbonohydrazonoy dicyanides 3a-c were synthesized and condensed with various hydrazine hydrate derivatives to produce the corresponding 3,5-diaminopyrazole derivatives 4-9, respectively. Fu...
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 5-SUBSTITUED 4-THIAZOLIDINONES WITH SULFANILAMIDE PHARMACOPHORE [0.03%]
含磺胺基团的噻唑烷酮衍生物的合成及其抗菌活性研究
Augusta Zevzikoviene,Andrejus Zevzikovas,Audronis Lukosius et al.
Augusta Zevzikoviene et al.
After incorporation pharmacophores of allylamine and sulfanilamide into 4-thiazolidinone's ring - no antimicrobial activity was determined. This outcome stimulated synthesis of new group - 5-substituted 4-thiazolidinones. In the literature ...
DESIGN, SYNTHESIS AND ANTICANCER ACTIVITY OF SOME NOVEL 1,2,4-TRIAZOLES CARRYING BIOLOGICALLY ACTIVE SULFONAMIDE MOIETIES [0.03%]
一类新型生物活性磺酰胺取代的1,2,4-三唑类化合物的设计、合成及抗肿瘤活性研究
Mostafa M Ghorab,Mansour S Alsaid,Mohammed Al-Dosari
Mostafa M Ghorab
Thirteen novel 1, 2, 4-triazoles incorporating a biologically active sulfonamide moieties 1-13 were designed and synthesized. The structures of the prepared compounds were elucidated on the basis of elemental analyses, IR, 'H-NMR, "C-NMR an...