BLOCKADE OF LARGE CONDUCTANCE CA(2+) ACTIVATED K(+) CHANNEL MAY PROTECT NEURONAL CELLS FROM HYPOXIA MIMETIC INSULT AND OXIDATIVE STRESS [0.03%]
阻断大电导钙激活的钾通道可能有助于保护神经元细胞免受缺氧和氧化应激损伤
Jin Zhang
Jin Zhang
Previous studies have linked neuronal cell death with changes of intracellular Ca(2+)([Ca(2+)](i)) homeostasis. Such changes of [Ca(2+)](I) has been noticed in various neurodegenerative models. It has also been suggested that K(+)channel, s...
2D LC HEART CUTTING ON-LINE OF PHENOLIC COMPOUNDS FROM THREE SPECIES OF THE GENUS SALIX [0.03%]
三種柳樹表皮酚類成分的二維液相心髒切片图在线分析
Loretta Pobłocka-Olech,Daniel Głód,Barbara Król-Kogus et al.
Loretta Pobłocka-Olech et al.
The 2D LC heart-cutting on-line system was elaborated and employed to the analysis of simple phenols and polyphenols occurring in willow barks. Using the test-set of 52 compounds, the conditions of chromatographic separation in each dimensi...
ANALYSIS OF ω-3 FATTY ACID CONTENT OF POLISH FISH OIL DRUG AND DIETARY SUPPLEMENTS [0.03%]
波兰鱼油药物和膳食补充剂中ω-3脂肪酸含量分析
Kamila Osadnik,Joanna Jaworska
Kamila Osadnik
Study results indicate that a diet rich in polyunsaturated fatty acids ω-3 (PUFA n-3) exerts favorable effect on human health, accounting for reduced cardiovascular morbidity and mortality. PUFA n-3 contained in marine fish oils, particula...
THE COMPARISON OF THE STABILITY INDICATING TWO HPLC METHODS AND THEIR APPLICATION FOR THE DETERMINATION OF BOSENTAN IN COATED TABLETS [0.03%]
两种HPLC法测定波生坦分散片含量的对比研究
Anna Zielińska,Sławek Wicherkiewicz,Wojciech Łuniewski et al.
Anna Zielińska et al.
Due to the raising requirements of drug quality, there is an increasing need for fast liquid separations of pharmaceutical substances with high efficiency and good resolution. The ultra-high pressure liquid chromatography (UHPLC) has been c...
Comparative Study
Acta poloniae pharmaceutica. 2016 Jul;73(4):865-874. DOI: 2016
DECOCTION PROCESS OPTIMIZATION AND QUALITY EVALUATION OF YI-HUANG DECOCTION BY HPLC FINGERPRINT ANALYSIS [0.03%]
基于HPLC指纹图谱的一黄汤的 decoction工艺优化及质量评价研究
Fangzhou Yin,Lin Li,Xin Li et al.
Fangzhou Yin et al.
Yi Huang decoction (YHD) has been used as one of famous traditional formula because of its unique effectiveness against gynecological diseases. YHD is composed of five herbs, including the rootstock of Dioscoma opposita Thunb. (Dioscoreacea...
Aneela Maalik,Syed Majid Bukhari,Asma Zaidi et al.
Aneela Maalik et al.
Chlorogenic acid (CGA; (IS,3R,4R.5R)-3-{[(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid) is a naturally occurring polyphenol mostly present in vegetables and fruits. CGA is a prominent component of ...
INHIBITORS OF LEUKOTRIENES SYNTHESIS: NOVEL AGENTS AND THEIR IMPLEMENTATION [0.03%]
白三烯合成抑制剂：新型药物及其应用
Krystyna Cegielska-Perun,Ewa Marczuk,Magdalena Bujalska-Zadrozny
Krystyna Cegielska-Perun
Leukotrienes (LTs) belong to pro-inflammatory mediators that are biosynthesized from arachidonic acid (AA), inter alia, by 5-lipoxygenase (5-LOX) enzyme in association with 5-LOX-activating protein (FLAP). An activation of LTs synthesis pat...
Chenglong Zheng,Yue Lan,Jian Zhang et al.
Chenglong Zheng et al.
Alzheimer's disease (AD), a neurodegenerative disorder, is associated with the mitochondrial dysfunction, defective synapses, and impaired cognition in elderly patients. The accumulation of amyloid β (Aβ) in synapses and synaptic mitochon...
EXPERIMENTALLY-INDUCED ANIMAL MODELS OF PREDIABETES AND INSULIN RESISTANCE: A REVIEW [0.03%]
糖尿病前期和胰岛素抵抗的实验动物模型研究进展述评
Md Shahidul Islam,Vijayalakshmi Venkatesan
Md Shahidul Islam
Animal models are very common in diabetes research when rodents are mostly used in this regard. Although a number of animal models of type 1 and type 2 diabetes (T2D) are developed in last few decades, the numbers of animal models of predia...
METHODS FOR OBTAINING POLY-ε-CAPROLACTONE FOR PRODUCING MICRO- AND NANOSCALE DRUG CARRIERS [0.03%]
聚-ε- caprolactone的制备及其作为微/纳米药物载体的应用方法研究
Tomasz Urbaniak,Witold Musiał
Tomasz Urbaniak
Poly-ε-caprolactone due to favorable properties including biocompatibiity, miscibility and controlled degradation is promising material for long term drug-delivery devices preparation, especially in blend with other polymers. Commercially ...