HPV-associated carcinoma of esophagus in the young: a case report and review of literature [0.03%]
青年食管癌的HPV感染相关性一例报告及文献复习
Chandralekha Tampi,Sandhya Pai,Vatsala M Doctor et al.
Chandralekha Tampi et al.
Esophageal carcinoma (EC) is rare in the younger age group, with only 15 cases reported in world literature. It is even rarer for an etiological agent to be implicated.A case of a 15-yr-old boy with squamous cell carcinoma of the esophagus ...
Lessons learned using Listeria monocytogenes as a live vector for HPV-associated tumors [0.03%]
有效抗肿瘤免疫治疗所需要的条件——利用李斯特菌作为载体治疗与HPV有关的肿瘤所获得的经验教训
S Farzana Hussain,Yvonne Paterson
S Farzana Hussain
As a vaccine vector, Listeria monocytogenes targets the innate immune system, resulting in a cytokine response that enhances antigen-presenting cell function as well as inducing a Th1 profile. It also enhances cell-mediated immunity by targ...
HPV-associated flat penile lesions in men of a non-STD hospital population: less frequent and smaller in size than in male sexual partners of women with CIN [0.03%]
与接受宫颈病变治疗的女性性伴侣相比，非性病医院男性患者中与人乳头状瘤病毒感染相关的阴茎扁平型病变发生率低且体积小
Maaike C G Bleeker,Cornelis J A Hogewoning,Feja J Voorhorst et al.
Maaike C G Bleeker et al.
Human papillomavirus (HPV) infections and HPV-associated penile lesions are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). To determine the significance of these findings, we studied the pre...
Detection of antibodies against a human papillomavirus (HPV) type 16 peptide that differentiate high-risk from low-risk HPV-associated low-grade squamous intraepithelial lesions [0.03%]
用于区分高危与低危人乳头瘤病毒所联低度鳞状上皮内病变的HPV型16肽段抗体检测方法
Leticia Rocha-Zavaleta,Juana P Ambrosio,Maria de Lourdes Mora-Garcia et al.
Leticia Rocha-Zavaleta et al.
A nonapeptide (16L1) was derived from the human papillomavirus type 16 (HPV-16) major capsid protein and tested for detection of potential cross-reactive serum IgG and cervical IgA antibodies in low- and high-risk HPV-associated low-grade s...
Comparative Study
The Journal of general virology. 2004 Sep;85(Pt 9):2643-2650. DOI:10.1099/vir.0.80077-0 2004
J P Klussmann,S Dinh,O Guntinas-Lichius et al.
J P Klussmann et al.
The major risk factors for head and neck squamous cell carcinomas (HNSCC) are considered to be tobacco and alcohol. A link between oncogenic types of the human papilloma virus (HPV) and the risk of HNSCC has been suggested in the literature...
TNFalpha polymorphism frequencies in HPV-associated cervical dysplasia [0.03%]
与HPV有关的宫颈上皮内瘤变中TNFα基因多态性的分布频率分析
A Kirkpatrick,J Bidwell,A J C van den Brule et al.
A Kirkpatrick et al.
Objectives: Persistent high-risk HPV infection of the uterine cervix is associated with CIN and cervical carcinoma. Women with a reduced pro-inflammatory response to HPV are likely to be susceptible to viral persistence, ...
Mark H Stoler
Mark H Stoler
Human papillomaviruses are present in virtually all cervical cancers and cancer precursors. Understanding the epithelial virology of this group of viruses has greatly influenced current concepts of cervical carcinogenesis, has provided a fr...
Absence of point mutation in codons 12 and 13 of K-RAS oncogene in HPV-associated high grade dysplasia and squamous cell cervical carcinoma [0.03%]
与HPV相关的高分化型宫颈癌和鳞状细胞宫颈癌中K-RAS致癌基因第12及13密码子无点突变
Tomasz Pochylski,Anna Kwaśniewska
Tomasz Pochylski
Objectives: Research data on the K-RAS gene mutation in carcinogenesis of the uterine cervix remain contradictory. Hence the question of whether spot mutations of the RAS genes or their excessive expression are an indispe...
Development of HPV vaccines for HPV-associated head and neck squamous cell carcinoma [0.03%]
人乳头瘤病毒相关头颈部鳞状细胞癌的HPV疫苗研发进展
Kalpana Devaraj,Maura L Gillison,T-C Wu
Kalpana Devaraj
High-risk genotypes of the human papillomavirus (HPV), particularly HPV type 16, are found in a distinct subset of head and neck squamous cell carcinomas (HNSCC). Thus, these HPV-associated HNSCC may be prevented or treated by vaccines desi...
Interleukin-2 inhibits proliferation of HPV-associated tumor cells and halts tumor growth in vivo [0.03%]
干扰素-2可抑制HPV相关肿瘤细胞增殖并阻止体内肿瘤生长
Patricia H Casana,Hector Hernandez,Manuel J Arana
Patricia H Casana
Previous studies have shown inhibition of cervical cancer cell growth by treatment with high concentrations of IL-2. In the present study, we evaluated the in vitro and in vivo effects of recombinant human IL-2 on HPV-associated tumor cells...
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