Endovascular repair of descending aorta lesions using a second-generation unibody single-branched stent-graft: a technical note [0.03%]
Zicheng Wan,Chang Shu
Zicheng Wan
Background: This report describes the second-generation unibody Cratos single-branched stent-graft for left subclavian artery (LSA) revascularization during thoracic endovascular aortic repair (TEVAR). ...
Evaluating the incidence of thrombosis in patients with concurrent second-generation androgen receptor inhibitor therapy and direct oral anticoagulants: A retrospective chart review [0.03%]
Zachary Larson,Cassia Griswold
Zachary Larson
Introduction: Many patients with prostate cancer have an indication for anticoagulation. This presents a pharmacokinetic dilemma as enzalutamide and apalutamide have significant effects on the metabolism of direct oral an...
Comparison of second-generation hydrogel embolic coils and bare platinum coils in ruptured intracranial aneurysm treatment: A prospective, multicenter, randomized controlled study [0.03%]
Seung Pil Ban,O-Ki Kwon,Young Deok Kim et al.
Seung Pil Ban et al.
To reduce the recurrence of cerebral aneurysms, second-generation hydrogel embolic coils (HECs) have been developed. We aimed to compare the impacts of bare platinum coils (BPCs) and HECs on the recurrence of ruptured intracranial aneurysms...
Second-Generation and Off-the-Shelf CAR Platforms: Emerging Cardiovascular Implications of Next-Generation Cellular Immunotherapies [0.03%]
Jatin Thukral,Pyush Moudgil,Abhay Mann et al.
Jatin Thukral et al.
Chimeric antigen receptor (CAR)-based therapies have become an integral part of modern cancer care, delivering durable responses in patients with otherwise refractory hematologic malignancies. As their use has expanded, it has become increa...
Second-Generation Crystalline Sponges Enabling Consistent Structure Analysis Under Standardized Conditions for Diverse Molecules [0.03%]
Wei He,Hiroki Takezawa,Makoto Fujita
Wei He
Crystallization is typically highly sensitive to even minor structural differences in target molecules. As a result, obtaining crystals of complex compounds often requires extensive trial-and-error experiments for each target molecule. We r...
Near-full-length genomic characterization and phylogenetic analysis of an HIV-1 CRF02_AG/G second-generation recombinant in Ningxia, China [0.03%]
Subinuer Mutalifu,ZiYang Luo,YouPing Duan et al.
Subinuer Mutalifu et al.
Inherited Trauma Across Generations: The Lived Experiences of Korean Second-Generation Atomic Bomb Survivors [0.03%]
跨越代际的继承创伤——韩国“原爆二世”的生活体验报告
Youngsub Yoon,Sihyun Park
Youngsub Yoon
The 1945 atomic bombings in Hiroshima and Nagasaki exposed a large population to radiation, resulting in significant deaths and disabilities. Despite the potential transgenerational effects-defined as the multidimensional impact of atomic b...
Aldosterone synthase inhibitors in hypertension and chronic kidney disease: double the benefit? [0.03%]
高血压和慢性肾脏病中的醛固酮合成酶抑制剂:收益翻番?
Alessio Mazzieri,Sara Battistoni,Gianpaolo Reboldi
Alessio Mazzieri
Summary: In randomized controlled trials, patients assigned to second generation ASIs had beneficial effects on blood pressure and albuminuria, with enhanced safety profiles.
A second generation of C3 humanized rats for preclinical evaluation of human C3 inhibitors [0.03%]
用于人C3抑制剂临床前评估的第二代人源化C3转基因大鼠
Jin Y Chen,Maojing Yang,Sweta Parab et al.
Jin Y Chen et al.
Complement component 3 (C3) is an attractive therapeutic target for several inflammatory diseases; however, the strict primate specificity of emerging C3 inhibitors mandates the use of nonhuman primates (NHPs) for preclinical evaluation, cr...
Investigation of the impacts of second-generation antihistamines on free-living marine nematodes and their interaction with ZnS nanoparticles: Mechanistic insights from community and population approaches and molecular interactions modeling [0.03%]
二代抗组胺药物对自由生活的海洋线虫及其与ZnS纳米颗粒相互作用的影响研究:从群落和种群方法以及分子相互作用模型机制入手的调查
Samir Ghannem,Houcine Labiadh,Sahar Ishak et al.
Samir Ghannem et al.
The current research investigates the impact of loratadine and its active metabolite desloratadine, applied at environmentally relevant concentrations (40 and 80 ng/L), using community-level, population-based, and molecular modeling approac...
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