Margaret V Becker,Anastasia Accoti,Angel Elma I Abu et al. Margaret V Becker et al.

Aedes aegypti mosquitoes are a major vector of arboviruses that oviposit in both artificial containers (i.e., buckets, tires, cans) and natural containers (i.e., coconut husks, tree holes). These diverse container types will seed the larvae...

Yijing Zhao,Anna D Metzler,Yangping Li et al. Yijing Zhao et al.

Zika virus (ZIKV) infection in human neural progenitors triggers DNA damage and activates DNA damage response, leading to cell cycle arrest that can retard brain development. Here, we link the ZIKV-induced S phase arrest to replication fork...

Pradeep Kumar N,Ajithlal P M,Prasanta Saini et al. Pradeep Kumar N et al.

An outbreak of Zika fever occurred in Thiruvananthapuram City, Kerala, India, during 2021. At the request of the Kerala state health administration, we investigated the same, towards proposing requisite containment strategies for the diseas...

Giuditta De Lorenzo,Rapeepat Tandavanitj,Lorena Preciado-Llanes et al. Giuditta De Lorenzo et al.

Zika virus (ZIKV) remained poorly studied until an outbreak in 2015 linked the virus to severe neurological disorders and congenital malformations. Currently, there are no antiviral drugs or vaccines available. We have previously demonstrat...

Jana Kerlik,Ján Hockicko,Mária Avdičová et al. Jana Kerlik et al.

Since 2019, when the first autochthonous cases of ZIKV disease were observed in EU/EEA countries, no other locally acquired ZIKV disease cases have been reported in EU/EEA. Our case of ZIKV disease in 2024 had a history of flying from Slova...

Quinn H Abram,Lindsay A Matthews,Alba Guarné et al. Quinn H Abram et al.

Flavivirus infections, including those of Dengue virus (DENV) and Zika virus (ZIKV), result in a high disease burden globally, yet many aspects of their viral life cycle remain poorly understood. For example, while some features of the mech...

Tim K Tsang,Diana P Rojas,Fei Xu et al. Tim K Tsang et al.

The 2015-2016 Zika virus outbreak in the Americas presented significant challenges in understanding the transmission dynamics due to substantial reporting biases, as women of reproductive age (15-39 years) were disproportionately represente...

Wailla Rafaela Barroso Mendes,Karla Fabiane Lopes de Melo,Francisco Canindé Ferreira de Luna et al. Wailla Rafaela Barroso Mendes et al.

Background: The Orthoflavivirus zikaense (ZIKV), a member of the Flaviviridae family, has been associated with severe neurological issues, particularly microcephaly, due to its ability to infect neural progenitor cells. T...

Haolong Cong,Xiaodong Han,Mengyuan Lv et al. Haolong Cong et al.

Zika virus (ZIKV) and Japanese encephalitis virus (JEV), two consequential mosquito-borne flaviviruses, induce severe systemic and neurotropic-encephalitic pathologies with overlapping symptoms profiles, complicating differential diagnosis ...

Timea Teglas,Silvia Torices,Anne Caroline Marcos et al. Timea Teglas et al.

Background : Zika virus (ZIKV) is a mosquito-borne Flavivirus with a strong affinity for the central nervous system (CNS). After infection, ZIKV can cross the blood-brain barrier (BBB) and reach the CNS, causing potential harm to both adult...