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Smári Freyr Kristjánsson,Sigurdur Olafsson,Magnús Gottfredsson et al. Smári Freyr Kristjánsson et al.
Background/Objectives: Direct-acting antiviral (DAA) therapy has been highly successful in treating chronic hepatitis C (CHC). The nationwide Treatment as Prevention of Hepatitis C (TraP HepC) initiative that was launched in Iceland in 2016...
Musyfira Sahra,Nurul Fitrayani,Abigael Alik Samma et al. Musyfira Sahra et al.
In commercial applications, sofosbuvir (SOF) for hepatitis C is only available in tablet dosage form, resulting in minimal SOF accumulation in the liver (26.94%) due to its low intestinal permeability and high molecular weight (529.5 Da). T...
Douglas Dietrich,Nancy Reau,Aijaz Ahmed et al. Douglas Dietrich et al.
The hepatitis C virus (HCV) testing and treatment pathway in the United States (US) includes a range of tests and appointments causing delays and loss to follow-up. We assessed the cost-effectiveness of simplifying the pathway using an econ...
Daisuke Nakamoto,Yi Piao,Hajime Mizutani et al. Daisuke Nakamoto et al.
Aims: This study was performed to evaluate patients' and physicians' preferences regarding hepatitis C virus (HCV) treatment in Japan, particularly focusing on direct-acting antivirals. Understanding these preferences is ...
Dilihuma Dilimulati,Nuerbiye Nueraihemaiti,Sendaer Hailati et al. Dilihuma Dilimulati et al.
An estimated 170 million people worldwide suffer from chronic hepatitis C virus (HCV) infection, which is the main reason for liver transplantation in numerous nations. Traditional Chinese medicine is also frequently employed in medicine to...
Yuko Nagaoki,Kenji Yamaoka,Yasutoshi Fujii et al. Yuko Nagaoki et al.
Background: It is not clear that antiviral therapy for hepatitis C virus (HCV) after recovery from curative treatment for hepatocellular carcinoma (HCC) has an effect on suppressing recurrence or improving survival rates....
Tanja Belčič Mikič,Igor Sterle,Mojca Matičič et al. Tanja Belčič Mikič et al.
Background: Since the discovery of successful direct-acting antiviral (DAA) treatment, kidneys from hepatitis C virus (HCV) RNA-positive donors represent a new opportunity to expand the organ donor pool for HCV-negative recipients. Case pre...
Jessica Obeysekare,Irene Pericot-Valverde,Snehal Lopes et al. Jessica Obeysekare et al.
Background: Anxiety disorders frequently occur in people who inject drugs (PWID). This study aimed to explore changes in anxiety among PWID during and after treatment of hepatitis C virus (HCV) with direct-acting antivira...
Naina Mohamed Pakkir Maideen,Rajkapoor Balasubramanian,Kumar Balasubramanian et al. Naina Mohamed Pakkir Maideen et al.
Background: Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV) can cause acute and chronic viral infections. Due to their higher costs, potential side effects and drug interactions, and associated risks, some patients wi...
Jim Young,Shouao Wang,Rachel Sacks-Davis et al. Jim Young et al.
Background: Successful treatment of hepatitis C virus (HCV) can lead to liver fibrosis regression. It is not known who will experience fibrosis regression or how quickly it will occur. ...
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