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Juan Ma,Chenliang Pan,Nan Bai et al. Juan Ma et al.
Keywords: IL-6; acute fulminant myocarditis; acute necrotizing encephalopathy; shock; tocilizumab (IL-6 inhibitor). © 2025 Ma, Pan, Bai, Zhang, Mi, Wa and Lu.
Jia Zhu,Min Kang,Yingjie Xu et al. Jia Zhu et al.
No significant differences were observed between the tocilizumab and infliximab treatment groups. Conclusion: ITA is primarily characterized by fever and hypertension, along with elevated inflammatory biomarkers....Both infliximab and tocilizumab demonstrated effective control of arterial inflammation.
Michael Macklin,Iazsmin Bauer Ventura,Dinesh Khanna Michael Macklin
Mycophenolate mofetil (MMF) has replaced cyclophosphamide (CYC) in most cases of SSc-ILD, with the recent addition of tocilizumab (TCZ) in SSc-ILD as well. Combination immunosuppressive (CI) therapy with rituximab (RTX) and MMF, along with the antifibrotic nintedanib, have also become options.
Kristina Lend,Jos Wr Twisk,Nupur Kumar et al. Kristina Lend et al.
Methods: In this post hoc analysis of the NORD-STAR trial, 296 newly diagnosed patients starting methotrexate with glucocorticoids, certolizumab pegol, abatacept or tocilizumab were included. Serum PCSK9 and LDL-cholesterol levels were measured at baseline and 24 weeks.
Lisa Christ,Luca Seitz,Godehard Scholz et al. Lisa Christ et al.
Objectives: The GUSTO (GCA treatment with Ultra-Short glucocorticoids (GC) and TOcilizumab (TCZ)) trial was set up to evaluate the efficacy and safety of a 52-week TCZ-monotherapy after a 3-day GC-pulse in new-onset GCA. ...
Cathryn Ann Rees,Aisling Butler,Shree Muthukrishnan et al. Cathryn Ann Rees et al.
Refractory to the conventional management of IRAEs with corticosteroids, the patient was successfully treated with intravenous immunoglobulins (IVIG), followed by tocilizumab and mycophenolate mofetil (MMF), ultimately resulting in complete radiological resolution of ADEM.
Ping Yi,Xing-Xing Zhang,Tian Tang et al. Ping Yi et al.
Therefore, once a child is diagnosed with idiopathic multicentric Castleman disease -TAFRO syndrome, early use of siltuximab should be considered for rapid disease control, followed by tocilizumab for maintenance therapy.
Johan Noble,Giorgia Comai,Valeria Corredetti et al. Johan Noble et al.
Chronic-active antibody mediated rejection (caAMR) is the leading causes of long-term kidney graft failure. Tocilizumab (TCZ), an anti-IL-6 receptor antibody, has been suggested as a treatment, but data are conflicting. We retrospectively s...
Yukako Maeda,Eitaro Hiejima,Kazushi Izawa et al. Yukako Maeda et al.
Cases that responded to tocilizumab and canakinumab were also reported. Earlier diagnosis was associated with higher rates of symptom- or drug-free status at the last follow-up visit.
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