Wenlong Shan,Zemin Wang,Chao Xie et al. Wenlong Shan et al.

This methodology enables efficient access to sulfone derivatives through an economical and environmentally benign protocol, exhibiting excellent compatibility with diverse substrates.

Nikhil Ji Tiwari,Rajneesh Misra Nikhil Ji Tiwari

) derivatives 1-3 was designed and synthesized via the Pd-catalyzed Buchwald-Hartwig cross-coupling reaction in good yields. 1-3 were treated with m-chloroperbenzoic acid (m-CPBA), which oxidizes the sulfur (S) atom in the thiazine ring to a sulfone, resulting in ferrocene substituted phenothiazine sulfone...derivatives 4-6....The photophysical behaviour indicates that the phenothiazine sulfone derivatives 4-6 exhibit a hypsochromic shift in the deep UV region of the UV-vis absorption spectrum as compared to 1-3....The redox behavior of 1-6 reveals that phenothiazine sulfone derivatives (4-6) exhibit shifts towards more positive oxidation potentials compared to their phenothiazine counterparts (1-3)....Phenothiazine sulfone derivatives (4-6) exhibit intermolecular hydrogen bonding within their crystal lattice, contributing to stabilizing their solid-state architecture.

Nicolas Fincias,Louis Clavier,Cora Escande de Messières et al. Nicolas Fincias et al.

We report here the first example of a copper-catalyzed transformation involving nitro allyl derivatives. This borylation reaction, which exploits the high versatility of the aforementioned precursor, tolerates a variety of functional groups...

Yong Zhang,Xin Luo,Mei Zhu et al. Yong Zhang et al.

To develop antibacterial agents with a novel mechanism of action, a series of sulfone compounds containing a 1,2,4-triazolo[4,3-a]pyridine were designed and synthesized by progressive molecular structure optimization. The antibacterial acti...

Pavel Davidovich,Dmitriy Nikolaev,Raniya Khadiullina et al. Pavel Davidovich et al.

In this study, we examine model cyclic vinyl sulfone derivatives as potential NRF2 activating probes. Previously, we and other authors have found anti-inflammatory properties of these compounds in in vivo models; however, the mechanism of action remained unknown.

Yong Zhang,Mei Zhu,Zongnan Zhu et al. Yong Zhang et al.

Background: Bacterial diseases in plants pose a serious threat to crop production, leading to substantial food loss every year. Prolonged and repeated use of a single antibacterial agent can promote resistance in pathogen...

Joy Mukhopadhyay,Subash C Sahoo,Prasad V Bharatam Joy Mukhopadhyay

Eight derivatives of the (imidazol-2-ylidene) → SR(+) systems were generated, and their sulfoxide and sulfone derivatives were obtained by oxidation using urea-H2O2 and mCPBA, respectively. The crystal structures of three compounds belonging to a series were determined.

Mohammad B M M Alkhatib,Marawan T H A Hussein,Mohammad A Alfantech et al. Mohammad B M M Alkhatib et al.

Novel geometrically asymmetric biscinnamyl-sulfone compounds (6a-c) with donor-π-conjugated spacer-acceptor functionality were successfully synthesized. This was achieved by coupling cinnamaldehyde precursors with 3,3'-diaminodiphenyl sulf...

Chieh-Yu Chang,Aaron Aponick Chieh-Yu Chang

Moreover, the use of sodium tert-butyldimethylsilyloxymethanesulfinate enables the collective synthesis of various chiral sulfone derivatives after simple transformations of the protected hydroxymethyl product.

Hengyue Zhang,Xingda Zhao,Ruihan Yan et al. Hengyue Zhang et al.

β-amino sulfones are important motifs found in natural products and active pharmaceutical compounds. Herein, we report a general and highly regioselective intermolecular aminosulfonylation of alkenes via the homolysis of sulfinyl oximes fr...