Jade Li,Adelaine K Leung,Yasushi Kondo et al.
Jade Li et al.
The core domain of small nuclear ribonucleoprotein (snRNP), comprised of a ring of seven paralogous proteins bound around a single-stranded RNA sequence, functions as the assembly nucleus in the maturation of U1, U2, U4 and U5 spliceosomal ...
Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis [0.03%]
剪接体U4 snRNA核心结构域的结构及其在snRNP生物发生中的作用
Adelaine K W Leung,Kiyoshi Nagai,Jade Li
Adelaine K W Leung
The spliceosome is a dynamic macromolecular machine that assembles on pre-messenger RNA substrates and catalyses the excision of non-coding intervening sequences (introns). Four of the five major components of the spliceosome, U1, U2, U4 an...
A common core RNP structure shared between the small nucleoar box C/D RNPs and the spliceosomal U4 snRNP [0.03%]
一个被小核粒仁素box C/D RNA粒子及剪接体U4小核仁RNA粒子共用的RNP基本结构
N J Watkins,V Ségault,B Charpentier et al.
N J Watkins et al.
The box C/D snoRNAs function in directing 2'-O-methylation and/or as chaperones in the processing of ribosomal RNA. We show here that Snu13p (15.5 kD in human), a component of the U4/U6.U5 tri-snRNP, is also associated with the box C/D snoR...