Differentiating Treatment-Resistant Depression With and Without Parkinsonism in the Elderly From a Psychiatric Perspective by 99mTc-TRODAT-1 SPECT Imaging [0.03%]
从精神病学角度通过99mTc-TRODAT-1单光子发射计算机断层成像术区分老年人中的伴帕金森氏征和不伴帕金森氏征的难治性抑郁治疗
Tung-Ping Su,Chiu-Jung Huang,Wei-Chung Mao et al.
Tung-Ping Su et al.
Objectives: Late-life depression often overlaps with neurodegenerative diseases leading to diagnostic and treatment challenges for neuropsychiatrists. This study aimed to differentiate elderly treatment-resistant depressi...
Development of a novel anti-CEACAM5 VHH for SPECT imaging and potential cancer therapy applications [0.03%]
用于SPECT成像和潜在癌症治疗应用的新型抗CEACAM5 VHH的开发
Ying Cong,Rianne Biemans,Natasja G Lieuwes et al.
Ying Cong et al.
Purpose: In this study, we investigated the utility of a novel developed anti-CEACAM5 VHH for cancer diagnosis and its potential of being a targeting-moiety of VHH-drug conjugates for cancer therapy. ...
Design and Characterization of Peptide-Conjugated Solid Lipid Nanoparticles for Targeted MRI and SPECT Imaging of Breast Tumors [0.03%]
用于乳腺肿瘤磁共振和单光子发射计算机断层显影成像的靶向肽结合固体脂质纳米颗粒的设计与表征
Tahereh Rahdari,Hossein Ghafouri,Sorour Ramezanpour et al.
Tahereh Rahdari et al.
Triple-negative breast cancer (TNBC) presents significant challenges due to its aggressive behavior and lack of targeted treatments. High-resolution imaging techniques and targeted nanoparticles offer potential solutions for early detection...
Development of 99mTc-labeled melanin-targeted probes for SPECT imaging of melanoma [0.03%]
99mTc标记的黑色素 targeted探针的制备及其体内外评价
Ji Tao,Rui Cao,Zhe Lei et al.
Ji Tao et al.
Purpose: Melanoma is a highly aggressive skin cancer with poor prognosis, highlighting the need for early detection. This study aims to develop a 99mTc-labeled single photon emission computed tomography (SPECT) probe targ...
Investigating cerebral blood flow in anxious dogs: a 99mTc-HMPAO SPECT imaging study [0.03%]
焦虑犬脑血流的探讨：一项99mtc-hmpao显像研究
Sofie Salden,Yangfeng Xu,Stefanie De Smet et al.
Sofie Salden et al.
Anxiety-related disorders have a significant effect on the welfare of pet dogs, often leading to behavioral problems and straining the human-animal bond. Conventional treatments sometimes prove inadequate, highlighting the need for a more o...
Fan Yang,Bowen Lei,Ziyuan Zhou et al.
Fan Yang et al.
SPECT is a widely used imaging modality in nuclear medicine which provides essential functional insights into cardiovascular, neurological, and oncological diseases. However, SPECT imaging suffers from limited quantitative accuracy due to l...
Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer [0.03%]
[99mTc]TcO-ABX474的发展：PSMA结合的锝-99m放射性配体的设计，合成和生物活性评价用于前列腺癌的SPECT成像
Christian Lis,Friedrich-Alexander Ludwig,Steffen Fischer et al.
Christian Lis et al.
A current global limitation to the timely and equitable patient access to PSMA-based therapies for prostate cancer (PCa) is the insufficient PET capacity for pretreatment imaging. However, the extensive global availability of SPECT cameras ...
[113mIn]In-AMBA: A Novel Diagnostic Agent for SPECT Imaging of GRPR-Expressing Tumors [0.03%]
[113m铟]In-AMBA：一种用于GRPR表达肿瘤SPECT成像的新诊断药物
Mohammad Moazami-Ashtiani,Saeed Rajabifar,Samaneh Zolghadri et al.
Mohammad Moazami-Ashtiani et al.
Purpose: Gastrin-releasing peptide receptor (GRPR), a member of the bombesin G-protein-coupled receptor family, is introduced as the promising target for the diagnosis and therapy of various tumors. This study aimed to de...
Investigation of a deep learning-based reconstruction approach utilizing dual-view projection for myocardial perfusion SPECT imaging [0.03%]
基于深度学习的双视角投影心肌灌注SPECT成像重建方法研究
Hui Liu,Yajing Zhang,Zhenlei Lyu et al.
Hui Liu et al.
Single-photon emission computed tomography (SPECT) is widely used in myocardial perfusion imaging (MPI) in clinic. However, conventional dual-head SPECT scanners require lengthy scanning times and gantry rotation, which limits the applicati...
Optical surface information-based respiratory phase-sorting and motion-incorporated reconstruction for SPECT imaging [0.03%]
基于光学表面信息的呼吸期相分类及运动融合重建在SPECT显像中的应用
Chenguang Li,Lucas A Polson,Xuzhou Wu et al.
Chenguang Li et al.
Background: Respiratory motion during the single photon emission computed tomography (SPECT) acquisition can cause blurring artifacts in the reconstructed images, leading to inaccurate estimates for activity and absorbed ...
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