Huizhu Wang,Miao Zhang,Ying Chen et al. Huizhu Wang et al.

Furthermore, the CPs served as nanocarriers for encapsulating the anti-inflammatory drug resveratrol (RSV) through hydrophobic interactions, serving as drug-loaded nanomicelles CP@RSV.

Tingting Li,Rulin Ma,Wennv Tang et al. Tingting Li et al.

Subsequently, interventions were performed with ferric ammonium citrate (FAC), deferoxamine (DFO), and resveratrol (RSV) to observe the effects of these interventions on iron metabolism and dedifferentiation in MIN6 cells.

Shengying Lin,Maggie Suisui Guo,Roy Wai-Lun Tang et al. Shengying Lin et al.

Vascular endothelial growth factor (VEGF), also known as VEGF-A, has been reported to mediate various diseases, including cancer and wet age-related macular degeneration (wAMD). Despite the fact that VEGF inhibitors are commercially availab...

Fabiola Zambrano,Pamela Uribe,Mabel Schulz et al. Fabiola Zambrano et al.

Moreover, natural compounds like resveratrol show pleiotropic effects by modulating neutrophil activation, ROS production, and protease activity.

Xiaoguang Liu,Sean Baxley,Michaeline Hebron et al. Xiaoguang Liu et al.

A previous multicenter, phase 2, double-blind, placebo-controlled trial randomized 179 participants into placebo or resveratrol over 52 weeks....Sub-analysis of CSF biomarkers of neuronal damage, inflammation, and microglial activity was performed in a subset of patients treated with a placebo (n = 21) versus resveratrol (n = 30)....Microglial activation was measured via a triggering receptor expressed on myeloid cells (TREM)-2 at baseline and after resveratrol treatment. Resveratrol significantly reduced CSF TREM2 levels and decreased inflammation and tissue damage, including matrix metalloprotease (MMP)-9....Cathepsin D, a lysosomal marker of autophagy, was reduced in the resveratrol group compared with placebo, while angiogenin, a marker of vascular angiogenesis, was increased....These data suggest that resveratrol may exert anti-inflammatory and neuroprotective effects in AD by reducing CSF TREM2 and other markers of neuronal damage.

Soyeon Kim,Changho Jhin,Sullim Lee et al. Soyeon Kim et al.

Keywords: antioxidant effect; dihydroresveratrol; melanogenesis; resveratrol; resveratrol derivative; tyrosinase.

Anika Singh,Yigong Guo,Maxine Cruz et al. Anika Singh et al.

This study was aimed to formulate oleogel-blueberry extract encapsulated systems with chitosan/polyethylene glycol (PEG) nanoparticles (NPs) to enhance resveratrol delivery and bioavailability while retaining bioactivity....HO oleogels showed the highest resveratrol delivery (P < 0.05) and superior chemical stability. Resveratrol release from HO improved bioactive penetration and intracellular antioxidant capacity in cultured Caco-2 intestinal cells, with no toxicity observed.

Julieta Ponce-Alonso,Luzmila Martínez-González,Ángel Gabriel Alpuche-Solís et al. Julieta Ponce-Alonso et al.

Objectives: The study aimed to express a synthetic nisin gene in the nucleus of the green microalga Scenedesmus acutus UTEX 72 and evaluate its antimicrobial activity in vitro against Staphylococcus aureus (ATCC 29213), E...

Zhijie Liang,Jinzhuai Li,Shuying Luo et al. Zhijie Liang et al.

Resveratrol (RSV), a natural polyphenol with potent antioxidant and anti-inflammatory properties, exhibits significant therapeutic potential for non-alcoholic fatty liver disease (NAFLD) by modulating lipid metabolism, oxidative stress, and...

Zhuo-Qun Ren,Sheng-Yuan Zheng,Zhengcheng Sun et al. Zhuo-Qun Ren et al.

Resveratrol (RES), a naturally occurring polyphenolic compound, has garnered significant attention due to its diverse biological activities, which include anti-inflammatory, antioxidant, and antiaging properties. This review synthesizes cur...