Ying-Chi Kao,Pei-Ching Yang,Yu-Ping Lin et al. Ying-Chi Kao et al.

These findings highlight the adaptability of MSC spheroid-derived 3D dECM for tissue-specific customization through straightforward and translatable growth factor incorporation, demonstrating its potential as a pro-regenerative biomaterial for advancing regenerative medicine applications.

Denise Sperlich,Katharina Becker,Ulrike Mau-Holzmann et al. Denise Sperlich et al.

This resource provides a valuable tool for disease modeling, drug discovery, and regenerative medicine applications. Copyright © 2025 The Author(s). Published by Elsevier B.V. All rights reserved.

Denisa Batir-Marin,Claudia Simona Ștefan,Monica Boev et al. Denisa Batir-Marin et al.

Furthermore, regenerative medicine strategies, including β-cell replacement, CRISPR-based gene editing, and immunomodulatory therapies, hold potential for disease modification.

Qiaoju Zhang,Xi Luo,Yuwen Zheng et al. Qiaoju Zhang et al.

This study establishes a scientific foundation for TSA-based interventions, with potential clinical implications in regenerative medicine and scar therapy. Copyright © 2025. Published by Elsevier Inc.

Fancheng Sun,Lexie W Q Xi,Wesley Luu et al. Fancheng Sun et al.

Clinical studies and observations have provided valuable knowledge and understanding of FECD, while preclinical studies are essential for gaining insights into disease progression and mechanisms for the development and testing of regenerative medicine therapies.

Junzhi Li,Jing Chu,Zhenlin Chen et al. Junzhi Li et al.

The innovative approach combines surface modification with organoids culture technique, offering significant potential for advancing bile duct regenerative medicine and developing more complex three-dimensional (3D) tissues in vitro.

Chao Li,Yipu Zhang,Yawei Du et al. Chao Li et al.

As a disruptive regenerative medicine technology, it has wide application prospects in the fields of organ development, gene editing, disease modeling, and precision therapy.

He Li,Xueting Pan,Tianyun Wang et al. He Li et al.

Tissue damage often causes considerable suffering to patients due to slow recovery and poor prognosis. The use of electroactive materials to deliver biophysical signals plays a key role in regulating tissue regeneration processes. Among the...

Aishik Chakraborty,Wei Luo,Arghya Paula Aishik Chakraborty

Liying Xiao,Zhaozhao Ding,Lili Wang et al. Liying Xiao et al.

Tissue regeneration in vivo happens in complex physiological microenvironments that usually involve versatile physical and biological gradients. Introducing controllable gradients to anisotropic biomaterials is critical for the next generat...