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Juan Pedro-Botet Juan Pedro-Botet
In addition to low-density lipoproteins (LDL), those containing apolipoprotein (Apo) B and with a diameter less than 70 nm, including the smaller triglyceride-rich lipoproteins, remnant particles, and lipoprotein(a), may independently contr...
Aishwarya Krishnaraj,Ehab Bakbak,Hwee Teoh et al. Aishwarya Krishnaraj et al.
Background: South Asians (SAs) represent ∼25% of the world's population and account for >50% of global cardiovascular (CV) deaths, yet they continue to be underrepresented in contemporary clinical trials. The REDUCE-IT s...
Jean Ferrières,Vincent Bataille,Etienne Puymirat et al. Jean Ferrières et al.
Background: The reduction of cardiovascular events with icosapent ethyl-intervention trial (REDUCE-IT) trial revealed robust atherosclerotic cardiovascular risk reduction with a strategy comprising high-dose omega-3 icosa...
William E Boden,Deepak L Bhatt,Peter P Toth et al. William E Boden et al.
The aims of this clinical review are to: (i) highlight the importance of elevated baseline triglycerides (TG) in the setting of well-controlled low-density lipoprotein cholesterol (LDL-C) on statins as a major contributor to residual athero...
Omar Sheikh,Anthony G Vande Hei,Ayman Battisha et al. Omar Sheikh et al.
Heart disease continues to affect health outcomes globally, accounting for a quarter of all deaths in the United States. Despite the improvement in the development and implementation of guideline-directed medical therapy, the risk of advers...