Combination Cytoreductive Surgery, Radiotherapy, or Ablation for De Novo Metastatic Prostate Cancer: The IP2-ATLANTA Internal Pilot, Phase 2, Randomised Controlled Trial [0.03%]
初始转移性前列腺癌联合细胞减灭术、放疗或消融的IP2-ATLANTA内部预试验二期随机对照试验
Martin J Connor,Taimur T Shah,Johanna Sukumar et al.
Martin J Connor et al.
Background and objective: Cytoreduction of the primary prostate cancer, involved lymph nodes, and metastases may confer improved cancer control in de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC). ...
Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS): an open-label, multicentre, randomised controlled trial [0.03%]
开放标签多中心随机对照试验评估腕管综合征的手术和皮质类固醇注射治疗(DISTRICTS)
Wijnand A C Palmbergen,Roy Beekman,A Marijne Heeren et al.
Wijnand A C Palmbergen et al.
Methods: We conducted an open-label, randomised controlled trial across 31 hospitals in the Netherlands.
Randomized Controlled Trial
Lancet (London, England). 2025 Jun 14;405(10495):2153-2163. DOI:10.1016/S0140-6736(25)00368-X 2025
Retifanlimab with carboplatin and paclitaxel for locally recurrent or metastatic squamous cell carcinoma of the anal canal (POD1UM-303/InterAACT-2): a global, phase 3 randomised controlled trial [0.03%]
关于局部晚期或转移性肛管鳞状细胞癌的Retifanlimab联合卡铂和白蛋白结合型紫杉醇治疗:一项全球III期随机对照试验(POD1UM-303/InterAACT-2)
Sheela Rao,Emmanuelle Samalin-Scalzi,Ludovic Evesque et al.
Sheela Rao et al.
Background: Retifanlimab has activity in programmed death ligand 1-positive advanced squamous cell anal carcinoma (SCAC) that has progressed on platinum chemotherapy. We aimed to prospectively assess the benefit of adding...
Effect of Horticultural Therapy Program on Psychological Wellbeing, Hope and Social Adjustment Among Patients With Psychotic Disorders: A Nursing Perspective [0.03%]
园艺疗法对精神病患者心理健康、希望和社会适应的影响:护理视角
Mohamed Hussein Ramadan Atta,Ehab A A Salama,Reem Farag Mahrous Menessy
Mohamed Hussein Ramadan Atta
Method: The study utilised a randomised controlled trial research design. A study and control group of 60 patients with a psychotic disorder was established.
Social, Digital and Community Capital Facilitated COVID-19 Pandemic Resilience in a Qualitative Survey of Older Adults With Mild Cognitive Concerns [0.03%]
社交、数字和社区资本在新冠肺炎大流行中促进轻度认知障碍老年人的韧性——定性调查
Annie Mae Wright,Harriet Demnitz-King,Alexandra Burton et al.
Annie Mae Wright et al.
We invited adults with mild cognitive concerns without dementia, aged ≥60 years participating in a randomised controlled trial of a psychosocial, secondary dementia prevention intervention, to complete a semi-structured survey, regarding how the pandemic impacted their lifestyle and wellbeing in areas
Online Cognitive-Behavioural Intervention to Manage Dental Anxiety: A 12-Month Randomised Clinical Trial [0.03%]
管理牙科焦虑的在线认知行为干预:一项为期12个月的随机临床试验
Marisol Tellez,Eugene M Dunne,Elizabeth Konneker et al.
Marisol Tellez et al.
A randomised controlled trial was conducted (N = 499) to test its efficacy.
A feasibility randomised trial evaluating the levitation tri-compartment offloader knee brace for multicompartment knee osteoarthritis [0.03%]
评估levitation三腔室膝关节支具治疗多部位膝骨关节炎可行性的随机试验
Emily L Bishop,Justin Bonhomme,Molly Joffe et al.
Emily L Bishop et al.
This feasibility study aimed to (i) evaluate the feasibility of conducting a full RCT, (ii) evaluate the distributional properties of the Visual Analog Scale (VAS) activity-specific knee pain score to estimate the sample size required for a full randomised controlled trial (RCT), and (iii) refine and
Youth co-production for sustainable engagement and empowerment in health (YiPEE): protocol for a cluster-randomised controlled trial of an intervention for mental health promotion among adolescents in schools in Chennai, India [0.03%]
印度金奈学校青少年心理健康促进干预集群随机对照试验(YiPEE)方案:可持续参与和赋权的青年合作生产
Vijaya Raghavan,Maria Niemi,Monika Martens et al.
Vijaya Raghavan et al.
Introduction: Adolescence is a time of rapid physical, social and psychological development and many risk factors for mental disorders have their roots in this age period. Primary prevention through school platforms has b...
Randomized Controlled Trial
BMJ open. 2025 Jun 13;15(6):e095671. DOI:10.1136/bmjopen-2024-095671 2025
Glucose variability and mode of anaesthesia in major noncardiac surgery (GlucoVITAL): study protocol for a randomised controlled trial [0.03%]
glucose variability和麻醉方式在重大非心脏手术中的作用(GlucoVITAL):随机对照试验研究方案
Henrike Janssen,Priyanthi Dias,Louise Hiller et al.
Henrike Janssen et al.
Background: Hyperglycaemia after noncardiac surgery occurs commonly and is associated with complications. The choice of maintenance anaesthesia may promote hyperglycaemia and increase glucose variability, both of which ex...
Clinical Trial
BJA open. 2025 May 24:14:100419. DOI:10.1016/j.bjao.2025.100419 2025
Chronic low back pain management: clinical and psychophysiological outcomes of multimodal approaches-a randomised controlled trial on yoga and mindfulness [0.03%]
慢性下背痛的管理:多模式方法的临床和心理生理结果——关于瑜伽和正念的随机对照试验
Yusra Saleem,Shamoon Noushad,Sadaf Ahmed et al.
Yusra Saleem et al.
This multicentre parallel-arm randomised controlled trial will compare the efficacy of yoga to MBSR for CLBP in healthcare providers.
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