Epigenetic markers of disease risk and psychotherapy response in anxiety disorders - a longitudinal analysis of the DNA methylome [0.03%]
焦虑症中疾病风险和心理治疗反应的表观遗传标志——DNA甲基组的纵向分析
Katharina Domschke,Miriam A Schiele,Óscar Crespo Salvador et al.
Katharina Domschke et al.
Epigenetic mechanisms such as DNA methylation are hypothesized to play a pivotal role in the pathogenesis of anxiety disorders and to predict as well as relate to treatment response. An epigenome-wide association study (EWAS) (Illumina Meth...
Criticality is Associated with Future Psychotherapy Response in Patients with Post-Traumatic Stress Disorder-A Pilot Study [0.03%]
关键症状与创伤后应激障碍患者未来心理治疗反应的关系：一项初步研究
Remko van Lutterveld,Myrthe Sterk,Cristian Spitoni et al.
Remko van Lutterveld et al.
Background: Trauma-focused psychotherapy is treatment of choice for post-traumatic stress disorder (PTSD). However, about half of patients do not respond. Recently, there is increased interest in brain criticality, which ...
Brain activity during reappraisal and associations with psychotherapy response in social anxiety and major depression: a randomized trial [0.03%]
社会焦虑和重度抑郁患者在再评价过程中的脑活动及其与心理治疗反应的关系：一项随机试验
Cope Feurer,Jagan Jimmy,Melissa Uribe et al.
Cope Feurer et al.
Background: Cognitive behavioral therapy (CBT) is an effective treatment for patients with social anxiety disorder (SAD) or major depressive disorder (MDD), yet there is variability in clinical improvement. Though prior r...
Childhood and adulthood trauma exposure: Associations with perinatal mental health and psychotherapy response [0.03%]
童年和成年期的创伤经历与围产期精神卫生和心理治疗反应之间的关系
Carolyn Ponting,Melissa Bond,Belén Rogowski et al.
Carolyn Ponting et al.
Trauma exposure is strongly linked to maternal posttraumatic stress disorder (PTSD) and depressive symptoms during the perinatal period; however, childhood trauma exposure is often assessed without accounting for adult exposure. This study ...
Clinical Trial
Journal of traumatic stress. 2024 Feb;37(1):178-186. DOI:10.1002/jts.22989 2024
Srishti Vashishtha,Stefan Kloiber,Gwyneth Zai
Srishti Vashishtha
However, current findings are inconsistent and thus do not support the use of genetic variants for the prediction of psychotherapy response in anxiety disorders. Copyright © 2023 Wolters Kluwer Health, Inc.
A polygenic-informed approach to a predictive EEG signature empowers antidepressant treatment prediction: A proof-of-concept study [0.03%]
一种基于多基因信息的预测性EEG标志物方法赋能抗抑郁药物治疗预测：概念验证研究
Hannah Meijs,Amourie Prentice,Bochao D Lin et al.
Hannah Meijs et al.
Finally, blinded out-of-sample validation of the network as predictor for psychotherapy response in another independent dataset (male, N=50) results in a within-subsample response rate of 50% (improvement of 56%).
Development of a model to predict psychotherapy response for depression among Veterans [0.03%]
开发模型预测退伍军人抑郁症心理治疗反应
Hannah N Ziobrowski,Ruifeng Cui,Eric L Ross et al.
Hannah N Ziobrowski et al.
We developed a machine learning (ML) model to predict psychotherapy response at 3 months using baseline survey, administrative, and geospatial variables in a 70% training sample.
Observational Study
Psychological medicine. 2023 Jun;53(8):3591-3600. DOI:10.1017/S0033291722000228 2023
Individual prediction of trauma-focused psychotherapy response in youth with posttraumatic stress disorder using resting-state functional connectivity [0.03%]
基于静息态功能连接的 PTSD 青少年患者个性化评估创伤聚焦心理治疗反应预测的研究
Paul Zhutovsky,Jasper B Zantvoord,Judith B M Ensink et al.
Paul Zhutovsky et al.
This study provides proof-of-concept evidence for the feasibility to predict trauma-focused psychotherapy response in youth with PTSD at an individual-level.
Anterior cingulate cortex activation during attentional control as a transdiagnostic marker of psychotherapy response: a randomized clinical trial [0.03%]
注意控制过程中前扣带皮层激活作为心理治疗反应的跨诊断标志物：一项随机临床试验
Cope Feurer,Jagan Jimmy,Runa Bhaumik et al.
Cope Feurer et al.
Anterior cingulate cortex (ACC) response during attentional control in the context of task-irrelevant emotional faces is a promising biomarker of cognitive behavioral therapy (CBT) outcome in patients with social anxiety disorder (SAD). How...
Integration of Well-Being Therapy and Positive Psychotherapy: A Response to Fava and Guidi's (2021) Commentary on Radstaak et al. (2020) [0.03%]
关于福瓦和朱迪(2021)对拉德斯塔克等人(2020)的评论：幸福疗法与积极心理治疗的融合
Mirjam Radstaak,Laura Hüning,Ernst T Bohlmeijer
Mirjam Radstaak
The results of our study on the effects of well-being therapy (WBT) compared with a treatment-as-usual (TAU) control condition among individuals with residual symptoms of posttraumatic stress disorder (PTSD) were recently published in the J...
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