Trends in Proton-Pump Inhibitor Use Among Danish Adults: A Nationwide Drug Utilization Study 2015-2023 [0.03%]
丹麦成人质子泵抑制剂使用趋势：一项全国范围内的药物利用研究（2015-2023年）
Karoline M Lundgaard,Morten Ø Christiansen,Heidi Sonne et al.
Karoline M Lundgaard et al.
The global increase in proton-pump inhibitor (PPI) use has raised concerns about their appropriate use, particularly due to potential overprescription and associated adverse effects.
Long-term Efficacy of Pediatric Anti-reflux Surgery in Reduction of Acid-reducing Medication [0.03%]
长期疗效：抗反流手术减少儿科患者抑酸药物用量
Meagan Rosenberg,Aixa Perez Coulter,Victoria Pepper et al.
Meagan Rosenberg et al.
Long-term proton-pump inhibitor and H2 antagonist use, however, is associated with infection and micronutrient malabsorption. This study investigates long-term ARP efficacy in decreasing acid-reduction medication (ARMs) usage.
Surgical Infection Society Multi-Center Observational Study: Empiric Anti-Fungal Coverage after Non-Colonic Gastrointestinal Perforation [0.03%]
胃肠道穿孔术后经验性抗真菌治疗的多中心观察研究
Andrea M Gochi,Wardah Rafaqat,Vahe Panossian et al.
Andrea M Gochi et al.
In multi-variable regression, American Society of Anesthesiologists physical status classification system (ASA) category 3 increased the risk of organ-space SSI (odds ratio [OR] 2.49, p = 0.04), whereas perioperative proton-pump inhibitor (PPI) use was protective (OR 0.15, p = 0.004).
Adherence to clinical guidelines for the evaluation and management of eosinophilic esophagitis among gastroenterologists in the Arab countries [0.03%]
阿拉伯国家胃肠病学家对嗜酸性食管炎评估和管理临床指南依从性的研究
Abdulrahman Al-Hussaini,Jaber Alrashidi,Mohamad Miqdady et al.
Abdulrahman Al-Hussaini et al.
The majority of the respondents (72%) did not require a trial of a proton-pump inhibitor (PPI) prior to making the diagnosis of EoE and 66% obtain biopsies from multiple esophageal levels.
Gastro-Oesophageal Reflux Disease Outcomes Following Roux-en-Y Gastric Bypass Surgery in Patients with Obesity: A Systematic Review and Meta-analysis [0.03%]
胃旁路手术治疗肥胖患者的胃食管反流病的结局：系统评价和 meta 分析
Narek Sargsyan,Iihan Ali,Christopher Namgoong et al.
Narek Sargsyan et al.
Postoperative DeMeester score improved by 16.49 points (95% CI 0.2-32.7; p ≤ 0.005) and 79.4% (95% CI 68.7-90.1; p = 0.01) completely discontinued proton-pump inhibitor therapy during the follow-up period.
Efficacy of Psyllium Husk as an Adjunct to PPI in Treating Laryngopharyngeal Reflux: A Clinical Perspective [0.03%]
燕麦壳作为 proton pump inhibitor 治疗梨形肌反流的辅助药物的有效性：临床视角
Amit Kumar Rana,Rohit Sharma,Mamta Verma et al.
Amit Kumar Rana et al.
Laryngopharyngeal reflux (LPR) is characterized by the retrograde flow of gastric contents into the laryngopharyngeal region, causing inflammation and nonspecific symptoms such as chronic cough, throat irritation, and hoarseness. Proton pum...
Potassium-competitive acid blocker versus proton-pump inhibitor in patients receiving antithrombotic therapy who are at high risk for gastrointestinal bleeding: Rationale and design of the randomized PROTECT- HBR trial [0.03%]
钾竞争性酸阻滞剂与质子泵抑制剂在使用抗栓药物的高胃肠道出血风险患者中的疗效及安全性：随机对照PROTECT-HBR研究的设计和原理
Jinho Lee,Han-Su Park,Junghoon Lee et al.
Jinho Lee et al.
Background: Concomitant use of proton pump inhibitor (PPI) is recommended in patients receiving chronic antithrombotic therapy who are at high risk of gastrointestinal (GI) bleeding. However, long-term safety and efficacy...
Shih-Wei Lai,Kuan-Fu Liao
Shih-Wei Lai
Stools from a human APOEe2 donor reduces amyloid and tau pathology and increases neuroinflammation in a 3xTg AD mouse model [0.03%]
来自人类APOEe2供体的粪便减轻了3xTg AD小鼠模型中的淀粉样蛋白和tau病理，并增加了神经炎症
Moira Marizzoni,Benjamin B Tournier,Claire Chevalier et al.
Moira Marizzoni et al.
FMT was done alone or in combination with antibiotic and proton-pump inhibitor following the Microbiota Transfer Therapy protocol (MTT).
Factors associated with treatment response in eosinophilic esophagitis patients: Experience from a pediatric tertiary care center [0.03%]
嗜酸细胞性食管炎患者治疗反应的相关因素：来自儿童三级护理中心的经验
Wimwipa Mongkonsritragoon,Ananya Varre,Serina Beydoun et al.
Wimwipa Mongkonsritragoon et al.
Among 656 of the 824 patients who had follow-up esophagogastroduodenoscopy, treatment response rates varied among modalities, with proton-pump inhibitor treatment exhibiting the highest response rate, at 60.8%, followed by diet modification (50%) and topical steroid treatment (43.5%).
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