The n-butanol extract of Polygonatum sibiricum improves spleen aging via p53 pathway [0.03%]
Polygonatum sibiricum的正丁醇萃取物通过p53途径改善脾脏衰老
Jingtong Chao,Yu Wang,Qidi Huang et al.
Jingtong Chao et al.
Background: Aging affects the function of multiple organs, including the spleen, which undergoes age-related structural changes and functional decline. Polygonatum sibiricum, a traditional anti-aging herbal medicine, cont...
Hepatoprotective mechanisms of ginkgo-Biloba and dandelion extracts: antioxidant activity and modulation of TNF-α and P53 pathways in Thioacetamide-induced liver injury [0.03%]
银杏和蒲公英提取物的保肝机制：抗氧化活性及调节硫代乙酰胺致肝损伤中TNF-α和P53通路的作用
Heba M Shaaban,El-Sayed E Mehana,Samah S Oda et al.
Heba M Shaaban et al.
Liver injuries, especially those induced by chemical toxins and pharmaceuticals, are increasingly prevalent. This study evaluated the hepatoprotective effects of Ginkgo biloba and dandelion extracts in a rat model of thioacetamide (TAA)-ind...
UXT enhances melanoma proliferation, migration, and invasion through modulation of the P53 signaling pathway [0.03%]
UXT通过调节P53信号通路促进黑色素瘤的增殖、迁移和侵袭
Kaifen Xiong,Chong Wang,Bingqian Hu et al.
Kaifen Xiong et al.
Melanoma is a highly malignant skin cancer with significant morbidity and mortality, and current treatments have shown limited efficacy in substantially improving clinical outcomes. This highlights an urgent need for alternative therapeutic...
An FGFR-p53 developmental signaling axis drives salivary cancer progression [0.03%]
FGFR-p53发育信号轴驱动唾液腺癌症发展
Adele M Musicant,Julia M R Billington,Jeffrey S Damrauer et al.
Adele M Musicant et al.
Mucoepidermoid carcinoma (MEC) is the most frequently occurring salivary gland malignancy. Here, we investigated transcriptomic profiles of human fetal and adult salivary glands and MEC tumors to assess programs involved in MEC progression....
Effects of zearalenone on endoplasmic reticulum stress-induced apoptosis via global and gene-specific histone modifications and miRNA-mediated p53-signaling pathway in HEK-293 cells [0.03%]
玉米赤霉烯酮通过组蛋白修饰和miRNA介导的p53信号通路在内质网应激诱导的人胚胎肾细胞系293细胞凋亡中的作用研究
Ecem Fatma Karaman,Mahmoud Abudayyak,Zeynep Rana Guler et al.
Ecem Fatma Karaman et al.
Zearalenone (ZEA), a non-steroidal estrogenic mycotoxin produced by Fusarium species, is well-known for its potent estrogen-like effects, which can lead to reproductive toxicity and toxicity in various organs. Although several studies have ...
Role of the SPI1/CDKN2A/p53 signaling pathway in cuproptosis of lung adenocarcinoma cells [0.03%]
SPI1/CDKN2A/p53信号通路在肺癌腺癌细胞铜死亡中的作用研究
Jiayue An,Wei Song,Qin Wang et al.
Jiayue An et al.
Lung adenocarcinoma (LUAD) is among the most prevalent malignancies worldwide. Cuproptosis, a copper-induced form of cell death, has been identified as a key process in LUAD progression; however, the molecular mechanisms underlying cupropto...
Lycium ruthenicum Murray Anthocyanins Alleviate Aging Through SIRT1/P53 Signaling Pathway [0.03%]
鲁梅氏枸杞中提取的花青素通过Sirtuin-1/p53信号通路发挥抗衰老功效
Jialin Liang,Zang Ga,Jiaqin Wu et al.
Jialin Liang et al.
Aging-related diseases have become a global health issue, with the escalating aging population leading to an increased disease incidence, placing immense pressure on individual health and society. Lycium ruthenicum Murray anthocyanins are h...
A highly selective and orally bioavailable casein kinase 1 alpha degrader through p53 signaling pathway targets B-cell lymphoma cells [0.03%]
一种通过p53信号通路高效降解乳清酸激酶1α的口服生物可利用化合物，并对B细胞淋巴瘤细胞具有靶向性
Shi Feng,Ran Kong,Cong Wang et al.
Shi Feng et al.
The modest reduction in casein kinase 1 alpha (CK1α) by lenalidomide contributes to its clinical effectiveness in treating del(5q) myelodysplastic syndrome. However, the mechanism by which CK1α impacts lymphoma survival remains inadequate...
The Immunotherapeutic Target ANLN Promotes Renal Clear Cell Carcinoma by Regulating PI3K/Akt and P53 Signaling Pathways [0.03%]
ANLN通过调节PI3K/Akt和P53信号通路促进肾透明细胞癌的免疫治疗靶点
Li Shan,Guo-Jian Gu,Cheng-Cheng Xiang et al.
Li Shan et al.
The role of Anillin (ANLN) in clear cell renal cell carcinoma (ccRCC) is not well understood. This study aimed to investigate the possible function and mechanism of ANLN in ccRCC. By using data from the Cancer Genome Atlas (TCGA), we assess...
METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle [0.03%]
METTL16通过诱导GTSE1的N6-甲基腺苷修饰来调节p53通路和细胞周期从而促进肺腺癌进展
Fang Liu,Sheng Jin
Fang Liu
Background: METTL16 has recently emerged as an N6-methyladenosine (m6A) methyltransferase that serves an integral role in tumor regulation. However, its involvement in lung adenocarcinoma (LUAD) remains unexamined. This i...
耗时 0.17196 秒，为您在
48206918
条记录里面共找到 1228 篇文章 [XML]