Haonan Xu,Fang Zhang,Yan Che et al. Haonan Xu et al.

Ethnopharmacological relevance: Thesium chinense Turcz. (TCT) is a traditional Chinese medicinal plant commonly used in clinical practice for respiratory diseases, known for its anti-inflammatory and antioxidant propertie...

Hang Du,Dongjin Wu,Tianyu Zhang et al. Hang Du et al.

Osteosarcoma (OS) is the most prevalent primary malignant bone tumor affecting children and adolescents. Despite ongoing research efforts, the 5-year survival rate has remained stagnant for many years, highlighting the critical need for nov...

Chenlu Li,Haolong Luo,Mengyuan Chen et al. Chenlu Li et al.

Bisphenol AF (BPAF), one of the most common bisphenol analogues, has been reported to exhibit higher estrogenic activity compared to bisphenol A (BPA) due to the presence of additional hydrophobic groups. To comprehensively understand the m...

Fu Du,Aotong Zhang,Xin Qi et al. Fu Du et al.

Therapeutic challenges persist in the management of non-small cell lung cancer (NSCLC) in oncology. Camptothecins have demonstrated as crucial agents in tumor therapy; however, their efficacy is significantly hindered by adverse effects and...

Yuan Sui,Xiaofei Dong,Enkang Tong et al. Yuan Sui et al.

Objective: The purpose of this study was to investigate the effects and mechanism of artemisinin (ART) on the proliferation, apoptosis, and inflammatory response of human dental pulp stem cells (HDPSCs) under lipopolysacc...

Xinze Liu,Lin Feng,Xin Jin et al. Xinze Liu et al.

Non-small cell lung cancer (NSCLC) is a malignant tumor with high morbidity and mortality. Ginsenosides have been shown to have strong antitumor activity, inhibiting tumor cell growth and promoting apoptosis. In this paper, the effects of g...

Fanwei Xia,Luping Wang,Ying Ji et al. Fanwei Xia et al.

Age-related macular degeneration (AMD) is the main cause of vision impairment in the elderly, which still lacks efficient treatment. Capilliposide A (LC-A), a saponin-type anti-inflammation compound extracted from Lysimachia capillipes Hems...

Penghui Nie,Ruiying Zhang,Tiantian Jia et al. Penghui Nie et al.

The global prevalence of premature ovarian failure (POF) is from 3.1 % to 4.3 %, which is a multifactorial disease including genetics, environmental and medical factors. However, the occurrence of POF is not well understood. To further expl...

Xin Xia,Wenjie Song,Fuyu Zhang et al. Xin Xia et al.

Hemifacial microsomia (HFM) is a rare congenital craniofacial deformity that significantly impacts the appearance and hearing. The genetic etiology of HFM remains largely unknown, although genetic factors are considered to be primary contri...

Joseph Lipsick Joseph Lipsick

The p53 tumor suppressor was first identified as a cellular protein that bound to the large T antigen in SV40-transformed cells. Initially thought to be the product of an oncogene, p53 turned out to be an anticancer protein whose loss or mu...