The orexin/hypocretin system in dementia-related neurological disorders: a double-edged sword in cognitive impairment [0.03%]
血管性痴呆和阿尔茨海默病相关的神经炎症标志物的研究进展——双刃剑假说在认知障碍中作用的启示
Chenyu Zhuang,Yuhan Cao,Jiayu Lu et al.
Chenyu Zhuang et al.
Its effects vary across disease stages, initially offering neuroprotection but later contributing to pathology. Moreover, OX's involvement in circadian rhythm regulation complicates its clinical utility, as disruptions exacerbate cognitive deficits.
G protein and MYD Growth Factor in neuroprotection after cerebral ischemia-reperfusion [0.03%]
脑缺血再灌注后神经保护中的G蛋白和MYD生长因子的作用机制研究
Yisheng Cheng,Xiaoxiao Cheng,Han Zhao et al.
Yisheng Cheng et al.
Plain language summary Gαi1/3is essential for MYDGF-induced endothelial cell proliferation.MYDGFpromotes p-S6K and ERK1/2 phosphorylation in HUVEC and MEC cells.Knockdownof Gαi1/3 impairs MYDGF neuroprotection in a CIRI mouse model.MYDGF-Gαi1/3signaling modulates angiogenesis
Propionate ameliorates neural degeneration by modulating mitochondrial fission and fusion in nerve cells [0.03%]
丙酸通过调节神经细胞中的线粒体分裂和融合来改善神经退行性病变
Song Xi,Tang Lin,Zhang Haiyan et al.
Song Xi et al.
Conclusion: Supplementation with propionate provides neuroprotection against neurodegenerative diseases.
Editorial: Neuroprotection Across Generations: Maternal Childhood Trauma and the Developing Amygdala [0.03%]
编辑来稿：跨世代神经保护作用：儿童时期的母系创伤与发育中的杏仁核
Giorgia Picci
Giorgia Picci
From neurotoxicity to neuroprotection: Rethinking GABAAR-targeting anesthetics [0.03%]
从神经毒理到神经保护：再思考作用于GABA受体的麻醉药
Yubao Li,Hongliang Yang,Lu Liu et al.
Yubao Li et al.
The brain growth spurt (BGS) represents a pivotal window in neurodevelopment, defined by rapid neurogenesis, heightened synaptogenesis, and the dynamic establishment of neural networks. During this phase, heightened brain plasticity signifi...
Exploring the role of glucagon-like peptide-1 receptor agonists in critical illness: mechanisms, benefits, and clinical implications [0.03%]
GLP-1受体激动剂在危重症中的作用：机制、益处和临床意义
Vidit G Jogani,Osman Mohamed Elfadil,Jithinraj Edakkanambeth Varayil et al.
Vidit G Jogani et al.
In the CNS, they provide neuroprotection by reducing neuroinflammation and pyroptosis. In the lungs, they attenuate ARDS by decreasing cytokine production, enhancing surfactant secretion, and restoring alveolar-capillary integrity. Renally, they reduce acute injury and preserve filtration function.
Polyphenols and Exercise in Mitochondrial Biogenesis: Focus on Age-Related CNS Disorders [0.03%]
植物化学物质和运动在线粒体生物发生中的作用：与年龄相关中枢神经系统疾病的关系
Junbiao Tu
Junbiao Tu
This review investigates the therapeutic potential of physical activity and polyphenols in modulating mitochondrial biogenesis and offering neuroprotection within the context of age-related CNS disorders.
Ginsenoside C-K inhibits Aβ oligomer-induced Alzheimer's disease pathology progression by regulating microglia-neuron interactions [0.03%]
人参皂苷CK通过调节小胶质细胞-神经元相互作用抑制Aβ寡聚体诱导的阿尔茨海默病病理进展
Chenghu Xie,Cunxin Zhang,Kefeng Zhang et al.
Chenghu Xie et al.
In HT22 neurons, GCK directly counteracted Aβ toxicity (apoptosis rate decreased from 38.7 % to 15.2 %) and exerted indirect neuroprotection by modulating microglia-derived conditioned medium (CM2 group showed a 2.1-fold increase in neuronal viability compared to CM1).
From Plant to Brain: Flavonoids in the Management of Obesity-Associated Cognitive Dysfunction [0.03%]
从植物到大脑：黄酮类化合物在肥胖相关认知障碍管理中的作用
P Berilli,P Berni,L Zandoná et al.
P Berilli et al.
Its modulatory effects occur directly and indirectly into the brain and three fronts of action are highlighted here: (1) restoring physiological processes altered in obesity; (2) promoting additional neuroprotection to the endogenous system; (3) improving neuroplasticity mechanisms that improve cognitive
Kynurenines and Mitochondrial Disturbances in Multiple Sclerosis [0.03%]
多发性硬化中 kisspeptin 与线粒体紊乱的关系
Daniel Pukoli,László Vécsei
Daniel Pukoli
In RRMS, heightened KP activity correlates with inflammation and neuroprotection attempts through increased KYNA production.
耗时 0.12026 秒，为您在
48229835
条记录里面共找到 10000 篇文章 [XML]