Fenugreek-derived exosome-like nanovesicles containing bioavailable phytoferritin for the management of iron deficiency anemia [0.03%]
从香蒲种子衍生的含生物有效量植物铁素的类外泌体纳米囊泡用于治疗缺铁性贫血
Cathrine M S Bethi,Meghana N Kumar,Sreeram P Kalarikkal et al.
Cathrine M S Bethi et al.
Thus, FGDNVs represent a natural iron nano-formulation for safe and efficient therapeutics for IDA.
Inhaled PAMAM-based nano-formulation prolonged lung retention for alleviating pulmonary inflammation of COPD [0.03%]
基于PAMAM的吸入型纳米制剂可延长肺滞留并缓解慢性阻塞性肺疾病所致肺部炎症
Chen Wang,Xiao-Yan Hu,Ri Ji et al.
Chen Wang et al.
Chronic obstructive pulmonary disease (COPD) stands as a predominant respiratory disorder intricately linked with respiratory tract microorganisms and their metabolites. Indole acetic acid (IAA), a derivative of tryptophan produced by Lacto...
Tweaking Unimolecular Micellar Nanoarchitecture for Drug Delivery in Tumor Xenograft Mice Models [0.03%]
用于肿瘤移植小鼠模型的药物递送的调节单分子胶束纳米结构
Shahidkhan Pathan,Manickam Jayakannan
Shahidkhan Pathan
Uncontrolled rapture of prodrug nano-formulation under physiological concentration gradient is a bottleneck in the effective delivery of anticancer drugs to solid tumors in vivo.
Effects of Nano-Quercetin on Cypermethrin Induced Liver Injury in Rabbits [0.03%]
纳米槲皮素对氯氰菊酯致兔肝损伤的影响
Maham Ashraf,Bushra Akhtar,Chi-Chung Chou et al.
Maham Ashraf et al.
The prepared nano-formulation was physically stable and fell within the nanoscale range (188.5 nm) with high entrapment efficiency (80.4%).
Hyaluronan-decorated-phloroglucinol-loaded mesoporous silica downregulates GLI1 and SMO genes of hedgehog signaling pathway in gastrointestinal cancer stem-like cells [0.03%]
透明质酸修饰的壳聚糖纳米粒负载异株茋提取物对结肠癌SW620细胞增殖、凋亡及侵袭能力的影响研究
Lakshmi Shanmugam,Megala Jayaraman
Lakshmi Shanmugam
Hence, hyaluronan-based mesoporous silica nano-formulation with phloroglucinol (MSN-PG-HA) was employed in our study to address the cancer relapse by targeting CD44....Moreover, MSN-PG-HA nano-formulation has shown a significantly higher efficacy than free PG in other cellular assays by controlling cell migration, colony and spheroid formation, inducing apoptosis and suppressing the elevated MMP levels, for all the three GI cell lines with p ≤ 0.05, highlighting the...Further, the gene and protein expression analyses of hedgehog signaling pathway components, such as GLI1 and SMO, showed a 0.7 to 0.8-fold decrease in expression with MSN-PG-HA treated groups, proving that our nano-formulation could significantly target CSC-related proteins.
Compacting hyaluronan into nanogels induces an enhanced macropinocytosis in MC38 cells [0.03%]
透明质纳米凝胶通过增强巨吞饮作用被摄取进入MC38细胞中
Wei Hou,Xinxin Hao,Jiayi Li et al.
Wei Hou et al.
Here, the cellular uptake of HA in linear form (HA conjugate) and nano-formulation (HA nanogels (NG)) were compared with a focus on macropinocytosis that is actively involved in nutrient scavenging for cancer cells.
Anti-Tumor Potential of Frankincense Essential Oil and Its Nano-Formulation in Breast Cancer: An In Vivo and In Vitro Study [0.03%]
乳香精油及其纳米制剂在乳腺癌中的抗肿瘤潜力：体内和体外研究
Nouran Mohamed,Hisham Ismail,Ghada M Nasr et al.
Nouran Mohamed et al.
Method: In this study, we investigated the anti-tumor effects of frankincense essential oil (FEO) and its nano-formulation with chitosan (FEO-CSNPs) using in vitro breast cancer models (MCF-7, MDA-MB-231, and 4T1 cells) and in vivo mouse mammary carcinoma (4T1) models (Balb/c).
Aerosol Delivery of Hesperetin-Loaded Nanoparticles and Immunotherapy Increases Survival in a Murine Lung Cancer Model [0.03%]
纳米颗粒递送含hesperetin药物及免疫疗法可提高小鼠肺癌模型的存活率
Sayeda Yasmin-Karim,Geraud Richards,Amanda Fam et al.
Sayeda Yasmin-Karim et al.
The Hesperetin nanoparticles (HNPs) were engineered using a nano-formulation microfluidic technique and polymeric nanoparticles. The in vitro studies were performed in human A549 (ATCC) and murine LL/2-Luc2 (ATCC) lung cancer cell lines.
Sparstolonin B nano-formulation attenuates LPS-induced lung injury [0.03%]
Sparstolonin B纳米制剂缓解脂多糖诱导的肺损伤
Qinghe Meng,Xiaojing Wang,Dandan Guo et al.
Qinghe Meng et al.
Our study examines the impact of a nano-formulation of Sparstolonin B (nSsnB), a TLR-4 antagonist, on LPS-induced inflammation in RAW264.7 cells and lung injury in mice.
Platelet membrane-camouflaged bioactive glass nano-formulations for enhanced drug delivery in the treatment of acute arterial thrombosis [0.03%]
用于急性动脉血栓治疗的促进药物输送的拟平板血小板膜纳米级生物活性玻璃配方
Minglin Ji,Qinying Tang,Olanrewaju Yaasir Olatunji et al.
Minglin Ji et al.
UK and TF were firstly incorporated onto BGs, and followed by a camouflage of polydopamine (PDA) and platelet membrane (PM) to form composite nano-formulation (TUBGs@PP)....This composite nano-formulation leverages the PM camouflage to enhance its biocompatibility, prolong circulation time in vivo, and extend the half-life of drugs....Additionally, as-fabricated TUBGs@PP composite nano-formulation can circumvent immune system-mediated clearance, thereby facilitating targeted drug delivery to the thrombus sites and enhancing the thrombolytic efficacy.
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